{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T15:16:02Z","timestamp":1778944562296,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Neonatal supraventricular tachycardia lacks neonatal\u2010specific evidence to guide therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively collected data of neonates with supraventricular tachycardia across two Italian centres between 2014 and 2024. Clinical features, mechanisms, echocardiography, biomarkers, acute and maintenance therapy were collected; outcomes included recurrences, intensive\u2010care admission, electrophysiology and ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010two infants were included (59% male; median onset 14\u2009days). Among the supraventricular tachycardia mechanisms, we identified atrioventricular reentrant tachycardia in 72%, AV\u2010nodal reentrant tachycardia in 9%, permanent junctional reciprocating tachycardia in 9%, focal atrial tachycardia in 9%. Median ejection fraction was 60% overall and 39% in those with heart failure; tachycardia\u2010induced cardiomyopathy occurred in 28%. First\u2010episode termination was spontaneous in 13%, achieved with vagal manoeuvres in 28% and adenosine in 47%. Maintenance therapy was required in 97% for a median of 21\u2009months. During a mean 3.75\u2010year Follow\u2010up, recurrence after withdrawal occurred in 3; electrophysiology was performed in 3 and ablation in 2. Elevated NT\u2010pro\u2010brain natriuretic peptide and focal atrial tachicardia\/permanent junctional reciprocating tachycardia phenotypes correlated with greater therapy burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Atrioventricular reentrant tachycardia predominates in neonatal supraventricular tachycardia. While acute control is usually attainable, sustained control often requires prolonged combination therapy. Early mechanism assignment and biomarker\u2010informed risk stratification may guide step\u2010up treatment, and catheter ablation is a viable option for refractory cases beyond infancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70472","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:30:24Z","timestamp":1770114624000},"page":"1210-1221","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Features, Management and Outcomes of Supraventricular Tachycardia in Newborns: A 10\u2010Year Multicenter Experience"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8250-6653","authenticated-orcid":false,"given":"Mattia","family":"Pasquinucci","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI) IRCCS Giannina Gaslini Institute  Genoa Italy"},{"name":"Department of Pediatrics AULSS 7 Pedemontana \u2013 San Bassiano Hospital  Bassano del Grappa Italy"},{"name":"The ABC Study on Heart Disease Foundation\u2010ONLUS  Conegliano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8140-8738","authenticated-orcid":false,"given":"Francesca Cotta","family":"Ramusino","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Padua University Hospital  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2493-3708","authenticated-orcid":false,"given":"Maria E.","family":"Derchi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology IRCCS Giannina Gaslini Institute  Genoa 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