{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:10:18Z","timestamp":1788883818663,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Sleep disruptions are common in hospitalised children. This study described sleep in critically ill and non\u2010critically ill hospitalised children, including young infants and patients with central nervous system injuries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This observational cohort study included two groups: critically ill children admitted to a paediatric intensive care unit with expected stay of \u2265\u200948\u2009h, and non\u2010critically ill children with suspected sleep disordered breathing. Critically ill children were recruited within two clinical studies conducted between 2020 and 2022. Non\u2010critically ill children were recruited from a retrospective database spanning between 2017 and 2021. Sleep was measured using polysomnography and compared with age\u2010specific reference ranges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 25 critically ill and 120 non\u2010critically ill children. Median ages were 3.6 (1.0\u201320.4) and 36.7 (6.1\u2013107.7) months, respectively. In critically ill children, nighttime total sleep time accounted for only 50.9% (49.5\u201355.5) of 24\u2009h sleep. Rapid eye movement (REM) and deep sleep were reduced in 96.0% and 66.7%, respectively. Electroencephalographic (EEG) abnormalities were common (76.0%). Non\u2010critically ill children had reduced REM sleep in early infancy and shorter, fragmented sleep in older children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Critically ill children had disrupted sleep and atypical EEG, while non\u2010critically ill children mainly had reduced fragmented sleep.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70666","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:21:23Z","timestamp":1782969683000},"page":"2323-2331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Critically Ill Children Show Disrupted Sleep Patterns and Atypical Electroencephalograms: An Observational Cohort Study"],"prefix":"10.1111","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0968-5400","authenticated-orcid":false,"given":"Eris","family":"van Twist","sequence":"first","affiliation":[{"name":"Division of Paediatric Intensive Care, Department of Neonatal and Paediatric Intensive Care Erasmus MC Sophia Children's Hospital  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnout B. 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T.","family":"Verbruggen","sequence":"additional","affiliation":[{"name":"Division of Paediatric Intensive Care, Department of Neonatal and Paediatric Intensive Care Erasmus MC Sophia Children's Hospital  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1604-3262","authenticated-orcid":false,"given":"Maartje","family":"Louter","sequence":"additional","affiliation":[{"name":"Division of Clinical Neurophysiology, Department of Neurology Erasmus MC  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karlien","family":"Veldscholte","sequence":"additional","affiliation":[{"name":"Division of Paediatric Intensive Care, Department of Neonatal and Paediatric Intensive Care Erasmus MC Sophia Children's Hospital  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen F. 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