{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:55:58Z","timestamp":1791550558487,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:00:00Z","timestamp":1786665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:00:00Z","timestamp":1786665600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004828","name":"Grand Challenges Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004828","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess long\u2010term effects of Kangaroo Mother Care (KMC) on motor development in adults born with birth weights \u2264\u20091800\u2009g, compared to conventional neonatal care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cohort analysis included 214 young adults with a history of birth weights \u2264\u20091800\u2009g, mostly preterm, originally enrolled in a randomized controlled trial between 1993 and 1994 evaluating KMC. Motor system development was assessed using transcranial magnetic stimulation (TMS) to measure corticospinal excitability and interhemispheric communication. Fine motor skills were evaluated with the Nine Hole Peg Test (9HPT). A 50 term\u2010born normal birth weight reference group provided TMS values to evaluate KMC effectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Individuals with history of birth weights \u2264\u20091800\u2009g, regardless of exposition to KMC, demonstrated longer completion times on the 9HPT and reduced grip strength compared to normative values. No significant differences in TMS measures were found between groups. However, in a multivariate logistic regression model, KMC was associated with a 78% effectiveness (95% confidence interval\u2014CI: 4%\u201395%) on preventing the altered transcallosal conduction time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Motor deficits related to low birth weight (LBW) persist into adulthood. KMC may contribute to avoid interhemispheric motor connectivity issues in individuals with birth weights \u2264\u20091800\u2009g, highlighting its potential for long\u2010term neurodevelopmental benefit.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70697","type":"journal-article","created":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T06:50:27Z","timestamp":1786776627000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Effects of Kangaroo Mother Care on Neuromotor Development in Adults Born Preterm: A Transcranial Magnetic Stimulation Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3754-0742","authenticated-orcid":false,"given":"Sandra Milena","family":"G\u00f3mez\u2010Ram\u00edrez","sequence":"first","affiliation":[{"name":"Facultad de Medicina, Maestr\u00eda en Neurociencias Universidad Nacional de Colombia  Bogot\u00e1 Colombia"},{"name":"Fundaci\u00f3n Canguro\/Kangaroo Foundation  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jairo Alberto","family":"Zuluaga\u2010G\u00f3mez","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Maestr\u00eda en Neurociencias Universidad Nacional de Colombia  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6697-5837","authenticated-orcid":false,"given":"Nathalie","family":"Charpak","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Canguro\/Kangaroo Foundation  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8735-6223","authenticated-orcid":false,"given":"Carlos","family":"Casta\u00f1eda\u2010Orjuela","sequence":"additional","affiliation":[{"name":"Epidemiology and Public Health Evaluation Group, Departamento de Salud P\u00fablica, Facultad de Medicina Universidad Nacional de Colombia  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01198-4"},{"key":"e_1_2_12_3_1","volume-title":"Guidelines on Optimal Feeding of Low Birth\u2010Weight Infants in Low\u2010 and Middle\u2010Income Countries [Internet]","author":"World Health Organization","year":"2011"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.14.04109"},{"key":"e_1_2_12_5_1","volume-title":"Preterm Birth. 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