{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:31:39Z","timestamp":1787142699627,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100014688","name":"Region Uppsala","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014688","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate parent\u2010reported psychiatric, neurodevelopmental and adaptive functioning outcomes in children with congenital cytomegalovirus (cCMV)\u2010related sensorineural hearing loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Parents of children aged 5\u201312\u2009years were recruited nationwide in Sweden into three groups: children with congenital cytomegalovirus\u2010related sensorineural hearing loss (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200910), children with non\u2010syndromic genetic hearing loss (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20099) and typically developing controls with normal hearing (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200923). Parents completed a background questionnaire, the Child Behaviour Checklist (CBCL) and the Five\u2010to\u2010Fifteen Revised (FTF\u2010R). Group differences were analysed using non\u2010parametric statistics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Children with congenital cytomegalovirus\u2010related hearing loss had later identification of hearing loss, delayed onset of independent walking and a higher prevalence of neurodevelopmental conditions compared with children with genetic hearing loss. They also had significantly higher parent\u2010reported psychiatric and developmental symptom levels than controls across all main clinical measures. Compared with the genetic hearing loss group, they demonstrated greater developmental difficulties, reduced social participation and poorer school functioning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Children with congenital cytomegalovirus\u2010related hearing loss exhibit a substantial burden of psychiatric and neurodevelopmental symptoms extending beyond hearing loss alone. These findings highlight the importance of early identification, structured long\u2010term follow\u2010up and tailored interventions to support this vulnerable population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70730","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:05:26Z","timestamp":1787141126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychiatric and Neurodevelopmental Outcomes in Swedish Children With Hearing Loss due to Congenital Cytomegalovirus Infection: A Cross\u2010Sectional Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2268-6608","authenticated-orcid":false,"given":"A.","family":"Michel Sandstr\u00f6m","sequence":"first","affiliation":[{"name":"Habilitation Center Norrlands University Hospital  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0380-2378","authenticated-orcid":false,"given":"E.","family":"Karltorp","sequence":"additional","affiliation":[{"name":"Department of Clinical Science Intervention and Technology, Karolinska Institute  Stockholm Sweden"},{"name":"Medical Unit Ear, Nose, Throat, Hearing and Balance Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0919-0384","authenticated-orcid":false,"given":"U.","family":"L\u00f6fkvist","sequence":"additional","affiliation":[{"name":"Department of Clinical Science Intervention and Technology, Karolinska Institute  Stockholm Sweden"},{"name":"Department of Public Health and Caring Sciences Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010021\u201000582\u2010z"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.02.018"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014\u20101173"},{"key":"e_1_2_12_5_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00006454-199202000-00007","article-title":"Symptomatic Congenital Cytomegalovirus Infection: Neonatal Morbidity and Mortality","volume":"11","author":"Boppana S. 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