{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:05:19Z","timestamp":1791515119206,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>A landmark trial published in 2021 demonstrated a 25% reduction in neonatal mortality when comparing immediate skin\u2010to\u2010skin contact (iSSC) to conventional care in infants with birthweight 1\u20131.8\u2009kg in low\u2010 and middle\u2010resource settings. New evidence from randomised clinical trials on iSSC in high\u2010resource settings has recently become available. This systematic review aimed to evaluate evidence for immediate\/early SSC, defined as initiated within 1\u2009h after birth, versus conventional care in inborn preterm infants in high\u2010resource settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten electronic databases, including PubMed, Embase, and Cochrane CENTRAL, from 2000 until February 2026, were searched. Randomised clinical trials comparing iSSC to conventional care in inborn preterm infants in high\u2010resource settings were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Four randomised clinical trials encompassing 325 infants were included. iSSC was feasible and safe. Cardiorespiratory stability, thermoregulation, breastfeeding practices, maternal\u2013infant interaction, infant stress regulation, and parental mental health outcomes were in favour of the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This systematic review provides updated evidence on the effectiveness of iSSC for preterm infants admitted to neonatal intensive care units in high resource settings. The findings support that there is a sensitive window in the first hours after birth when preterm infants and parents should not be separated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apa.70739","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T05:07:48Z","timestamp":1787720868000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Immediate Skin\u2010to\u2010Skin Contact in Preterm Infants in High\u2010Resource Settings: A Systematic Review"],"prefix":"10.1111","author":[{"given":"Victoria","family":"Rettedal","sequence":"first","affiliation":[{"name":"Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen 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