{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:12:12Z","timestamp":1789809132868,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:00:00Z","timestamp":1789776000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"abstract":"ABSTRACT<\/jats:title>\n \n Aim<\/jats:title>\n To determine incidence and risk factors associated with late\u2010onset hypoglycemia in extremely preterm or extremely low birth weight infants.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Retrospective single\u2010center cohort study including infants with a gestational age <\u200928\u2009weeks or birth weight <\u20091000\u2009g. Late\u2010onset hypoglycemia was defined as any blood glucose level <\u20092.6\u2009mmol\/L occurring after Day 7 of life in infants on full enteral nutrition.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Out of 211 included infants, 41 (19.4%) experienced at least one episode of late\u2010onset hypoglycemia. Late\u2010onset hypoglycemia was negatively associated with gestational age (\n p<\/jats:italic>\n \u2009=\u20090.013), birth weight (\n p<\/jats:italic>\n \u2009<\u20090.001), birth weight\n z<\/jats:italic>\n \u2010score (\n p<\/jats:italic>\n \u2009<\u20090.001) and maternal arterial hypertension (\n p<\/jats:italic>\n \u2009=\u20090.003).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The risk of late\u2010onset hypoglycemia is considerable in infants with a gestational age <\u200928\u2009weeks or birth weight under 1000\u2009g. Therefore, careful glucose monitoring beyond the first week of life is recommended for this vulnerable population.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/apa.70759","type":"journal-article","created":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T08:31:41Z","timestamp":1789806701000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence and Risk Factors of Late\u2010Onset Hypoglycemia in Extremely Low Gestational Age or Extremely Low Birth Weight Infants"],"prefix":"10.1111","author":[{"given":"Lara","family":"Canova","sequence":"first","affiliation":[{"name":"Department of Neonatology University Children's Hospital Basel UKBB, University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7536-5341","authenticated-orcid":false,"given":"Roland P.","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Neonatology University Children's Hospital Basel UKBB, University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven M.","family":"Schulzke","sequence":"additional","affiliation":[{"name":"Department of Neonatology University Children's Hospital Basel UKBB, University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,19]]},"reference":[{"issue":"6","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1159\/000104174","article-title":"Glucose Regulation in Preterm Newborn Infants","volume":"68","author":"Mitanchez D.","year":"2007","journal-title":"Hormone Research"},{"issue":"4","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1542\/pir.2016-0063","article-title":"Neonatal Hypoglycemia","volume":"38","author":"Thompson\u2010Branch A.","year":"2017","journal-title":"Pediatrics in Review"},{"issue":"5","key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.jpeds.2012.05.022","article-title":"Incidence of Neonatal Hypoglycemia in Babies Identified as at Risk","volume":"161","author":"Harris D. 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