{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T16:06:55Z","timestamp":1792858015911,"version":"4.5.0"},"reference-count":173,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T00:00:00Z","timestamp":1674432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005366","name":"Universitetet i Oslo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Physiologica"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cardiac cell death after myocardial infarction release endogenous structures termed damage\u2010associated molecular patterns (DAMPs) that trigger the innate immune system and initiate a sterile inflammation in the myocardium. Cardiomyocytes are energy demanding cells and 30% of their volume are mitochondria. Mitochondria are evolutionary endosymbionts originating from bacteria containing molecular patterns similar to bacteria, termed mitochondrial DAMPs (mDAMPs). Consequently, mitochondrial debris may be particularly immunogenic and damaging. However, the role of mDAMPs in myocardial infarction is not clarified. Identifying the most harmful mDAMPs and inhibiting their early inflammatory signaling may reduce infarct size and the risk of developing post\u2010infarct heart failure. The focus of this review is the role of mDAMPs in the immediate pro\u2010inflammatory phase after myocardial infarction before arrival of immune cells in the myocardium. We discuss different mDAMPs, their role in physiology and present knowledge regarding their role in the inflammatory response of acute myocardial infarction.<\/jats:p>","DOI":"10.1111\/apha.13920","type":"journal-article","created":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T23:54:36Z","timestamp":1673222076000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Mitochondria\u2010derived damage\u2010associated molecular patterns and inflammation in the ischemic\u2010reperfused heart"],"prefix":"10.1111","volume":"237","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9360-2681","authenticated-orcid":false,"given":"May\u2010Kristin","family":"Torp","sequence":"first","affiliation":[{"name":"Division of Physiology, Department of Molecular Medicine Institute of Basic Medical Sciences, University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarle","family":"Vaage","sequence":"additional","affiliation":[{"name":"Division of Physiology, Department of Molecular Medicine Institute of Basic Medical Sciences, University of Oslo Oslo Norway"},{"name":"Institute of Clinical Medicine University of Oslo Oslo Norway"},{"name":"Department of Research and Development, Division of Emergencies and Critical Care Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e5re\u2010Olav","family":"Stensl\u00f8kken","sequence":"additional","affiliation":[{"name":"Division of Physiology, Department of Molecular Medicine Institute of Basic Medical Sciences, University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.117.308903"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.113.300268"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00832"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.005015"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2018.01.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065X.2000.917309.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0351449"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2014.01.062"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2686"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/35066006"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0800028"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2011.01.008"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303577"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12118"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-12-188"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034730"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201202382"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-018-0686-x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-016-0553-6"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn292"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.243162"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.008788"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11897-017-0343-y"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2014.28"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.01.069"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(92)93381-S"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2873"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-018-0064-2"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-006-9196-2"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.283.5407.1476"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.155.1.264"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181a001ae"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2975"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1657"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2011.01.012"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140105"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/290457a0"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.53.070184.003041"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00220-13"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012311108"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2006.11.024"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201949799"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2015.6407"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201899238"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.01.009"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0703328"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1229963"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1980"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20170714"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-1703"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvy254"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2009.96"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-05-573543"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.04.047"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10992"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.117.309017"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-014-0459-0"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14830"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature18629"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201694696"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvt091"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5271251"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-03157-7"},{"issue":"4","key":"e_1_2_9_65_1","article-title":"Circulating cell\u2010free mtDNA contributes to AIM2 inflammasome\u2010mediated chronic inflammation in patients with type 2 diabetes","volume":"8","author":"Bae JH","year":"2019","journal-title":"Cell"},{"issue":"13","key":"e_1_2_9_66_1","first-page":"2639","article-title":"AIM2\u2010driven inflammasome activation in heart failure","volume":"117","author":"On\u00f3di Z","year":"2021","journal-title":"Cardiovasc Res"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep00786"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090613"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.76.060305.152028"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.suppl_2.11"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1113\/eph8802514"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1195491"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.01.020"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004410051042"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.190.5.741"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2016.02.005"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu224"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.10.074"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2016.08.010"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2016.08.006"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2017.00090"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2013.10.012"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.66.1.199"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.08.001"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2011.01.010"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2015.00083"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80434-1"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4400981"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4400883"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00468.2006"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh406"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-020-0230-3"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.03.010"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2009.06.002"},{"issue":"1285","key":"e_1_2_9_95_1","article-title":"Mammalian target of rapamycin (mTOR) and the proteasome attenuates IL\u20101\u03b2 expression in primary mouse cardiac fibroblasts","volume":"10","author":"Torp M\u2010K","year":"2019","journal-title":"Front Immunol"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2005.04.013"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08296"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2035027"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2012.09.003"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101375"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13909"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-014-0078-2"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.4.1907-1916.2005"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15127"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.010908.163111"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2011.00013"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-030409-101311"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.56.5.786"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.2000.6029"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(02)00442-X"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00158.2018"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1996.0163"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00032.2006"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2006.08.014"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-008-9366-1"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI69830"},{"issue":"109","key":"e_1_2_9_117_1","first-page":"41","article-title":"Study of non\u2010muscle cells of the adult mammalian heart: a fine structural analysis and distribution","volume":"28","author":"Nag AC","year":"1980","journal-title":"Cytobios"},{"key":"e_1_2_9_118_1","article-title":"Isolation, culture and transduction of adult mouse cardiomyocytes","volume":"114","author":"Judd J","year":"2016","journal-title":"Journal of Visualized Experiments"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.308139"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.113.300376"},{"issue":"5","key":"e_1_2_9_121_1","first-page":"s5","article-title":"The cardiomyocyte as a source of cytokines in cardiac injury","volume":"2012","author":"Aoyagi T","year":"2011","journal-title":"J Cell Sci Therapy"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.4.546"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.20307"},{"key":"e_1_2_9_124_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.307778"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.25624"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.03.122"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2012.07.003"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2016.11.003"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666170407123522"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0165-0"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-017-0663-9"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/cti2.1109"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118095"},{"key":"e_1_2_9_134_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1999.0989"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-018-0692-z"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00044-3"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1987.63.4.1481"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00017.2002"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0059989"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.FPJ03036X"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-016-0546-5"},{"key":"e_1_2_9_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-014-0415-z"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2000.279.2.L302"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000194074.59584.42"},{"key":"e_1_2_9_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(56)90127-9"},{"issue":"5","key":"e_1_2_9_146_1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.0954-6820.1976.tb08251.x","article-title":"Immunoglobulins and complement in chronic myocardial disease. A myocardial biopsy study","volume":"200","author":"Hatle L","year":"1976","journal-title":"Acta Med Scand"},{"issue":"5","key":"e_1_2_9_147_1","first-page":"645","article-title":"The role of activated complement and granulocytes in shock states and myocardial infarction","volume":"98","author":"Jacob HS","year":"1981","journal-title":"J Lab Clin Med"},{"issue":"1","key":"e_1_2_9_148_1","first-page":"13","article-title":"Free radicals and myocardial ischemia and reperfusion injury","volume":"110","author":"Simpson PJ","year":"1987","journal-title":"J Lab Clin Med"},{"issue":"2","key":"e_1_2_9_149_1","first-page":"I85","article-title":"Possible role for cytotoxic oxygen metabolites in the pathogenesis of cardiac ischemic injury","volume":"66","author":"Shlafer M","year":"1982","journal-title":"Circulation"},{"issue":"2","key":"e_1_2_9_150_1","first-page":"S63","article-title":"Myocardial reperfusion injury: an inflammatory reaction?","volume":"48","author":"Vaage J","year":"1989","journal-title":"Biomed Biochim Acta"},{"key":"e_1_2_9_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/0748-5514(85)90013-3"},{"key":"e_1_2_9_152_1","doi-asserted-by":"publisher","DOI":"10.3109\/14017439009098073"},{"key":"e_1_2_9_153_1","first-page":"145","article-title":"Molecular evidence for a border zone vulnerable to inflammatory reperfusion injury","volume":"106","author":"Youker KA","year":"1993","journal-title":"Trans Assoc Am Phys"},{"key":"e_1_2_9_154_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvy145"},{"key":"e_1_2_9_155_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0807646"},{"key":"e_1_2_9_156_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.67.6.1290"},{"key":"e_1_2_9_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90817-4"},{"key":"e_1_2_9_158_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7553.1302"},{"key":"e_1_2_9_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90603-2"},{"key":"e_1_2_9_160_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1707914"},{"key":"e_1_2_9_161_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa659"},{"key":"e_1_2_9_162_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcaa045"},{"key":"e_1_2_9_163_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw171"},{"key":"e_1_2_9_164_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc12735"},{"key":"e_1_2_9_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2003.09.042"},{"key":"e_1_2_9_166_1","doi-asserted-by":"publisher","DOI":"10.14503\/THIJ-14-4254"},{"issue":"10","key":"e_1_2_9_167_1","article-title":"Interleukin\u20106 and the risk of adverse outcomes in patients after an acute coronary syndrome: observations from the SOLID\u2010TIMI 52 (stabilization of plaque using Darapladib\u2010thrombolysis in myocardial infarction 52)","volume":"6","author":"Fanola CL","year":"2017","journal-title":"Trial Journal of the American Heart Association"},{"key":"e_1_2_9_168_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095073"},{"key":"e_1_2_9_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08780"},{"key":"e_1_2_9_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2017.02.014"},{"key":"e_1_2_9_171_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12265-018-9848-3"},{"key":"e_1_2_9_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2016.06.013"},{"key":"e_1_2_9_173_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-015-0470-0"},{"key":"e_1_2_9_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2012.12.002"}],"container-title":["Acta Physiologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apha.13920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/apha.13920","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apha.13920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T01:25:19Z","timestamp":1701653119000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apha.13920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,23]]},"references-count":173,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1111\/apha.13920"],"URL":"https:\/\/doi.org\/10.1111\/apha.13920","archive":["Portico"],"relation":{},"ISSN":["1748-1708","1748-1716"],"issn-type":[{"value":"1748-1708","type":"print"},{"value":"1748-1716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,23]]},"assertion":[{"value":"2022-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13920"}}