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However, there are no clear guidelines on the optimal method of determining kidney function in patients with cancer. We aimed to summarize the evidence on estimation of kidney function in patients with cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We searched PubMed for literature discussing the performance of GFR estimating equations in patients with malignancy to create a table of the evidence for creatinine\u2010 and cystatin c\u2010based equations. We further reviewed novel estimation techniques such as panel eGFR, real\u2010time measured GFR, and functional magnetic resonance imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The commonly used GFR estimating equations were derived from populations of patients without cancer. These equations may be less applicable in Oncology due to severe sarcopenia, inflammation, and other physiologic changes in patients with cancer. The Cockcroft\u2010Gault equation currently dominates in clinical Oncology despite significant limitations and accumulating evidence for use of the CKD\u2010EPI\n                      <jats:sub>Cr<\/jats:sub>\n                      formula. Additional considerations in the practice of Oncology include a recently developed equation (CamGFRv2, also called the Janowitz formula) and the use of cystatin c\u2010based equations to overcome some of the barriers to accurate GFR estimation based on creatinine alone.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Overall, we suggest using the CKD\u2010EPI equations (either cystatin c or creatinine\u2010based) among patients with cancer in routine clinical practice and measured GFR for patients at a critical threshold for treatment decisions.<\/jats:p>\n                  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