{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:12:35Z","timestamp":1759104755149},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T00:00:00Z","timestamp":1387497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>The aim of this study was to characterize plasmid\u2010mediated AmpC (<jats:styled-content style=\"fixed-case\">pA<\/jats:styled-content>mpC)\u2010producing E<jats:italic>scherichia coli<\/jats:italic> clinical isolates. A total of 101 strains with AmpC\u2010susceptibility pattern were prospectively included. All isolates were tested by multiplex PCR to detect different <jats:italic>bla<\/jats:italic> genes. Phylogenetic groups were determined by a multiplex PCR assay. Antimicrobial susceptibility was tested by a microdilution commercial method. Presence of <jats:italic>bla<\/jats:italic>pAmpC was detected in 79 (78.2%) of the strains; in these <jats:styled-content style=\"fixed-case\">pA<\/jats:styled-content>mpC\u2010producing isolates, <jats:italic>bla<\/jats:italic>TEM was detected in 41 (51.9%) strains, <jats:italic>bla<\/jats:italic>SHV in 5 (6.3%) strains, <jats:italic>bla<\/jats:italic>OXA in 3 (3.8%) strains, and <jats:italic>bla<\/jats:italic>CTX\u2010M in 3 (3.8%) strains. <jats:italic>bla<\/jats:italic>VIM and <jats:italic>bla<\/jats:italic>KPC were detected in one strain. Sixteen strains belonged to phylogroup A, 27 to B1, 20 to B2, and 16 to D. As conclusion, the majority of the strains of <jats:italic>E. coli<\/jats:italic> with AmpC\u2010susceptibility pattern are <jats:styled-content style=\"fixed-case\">pAmpC<\/jats:styled-content> positive, although the association of extended\u2010spectrum beta\u2010lactamases (<jats:styled-content style=\"fixed-case\">ESBL<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">pAmpC<\/jats:styled-content> is unusual.<\/jats:p>","DOI":"10.1111\/apm.12214","type":"journal-article","created":{"date-parts":[[2013,12,21]],"date-time":"2013-12-21T05:04:40Z","timestamp":1387602280000},"page":"796-799","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Diversity of <i>bla<\/i> genes and low incidence of <scp>CTX<\/scp>\u2010M in plasmid\u2010mediated AmpC\u2010producing <i>Escherichia coli<\/i> clinical 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