{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:35:32Z","timestamp":1785818132405,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T00:00:00Z","timestamp":1446768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2015,12]]},"abstract":"To assess the acute effects of partial splenic embolization (PSE<\/jats:styled-content>) on portal and splanchnic hemodynamics in patients with cirrhosis. Ninety\u2010five patients with hypersplenism were included in the study. Duplex examinations were performed before and 3 and 7\u00a0days after PSE<\/jats:styled-content>. Portal and splanchnic hemodynamics including vessel cross\u2010sectional area (CSA<\/jats:styled-content>), mean flow velocities (cm\/s), blood flows (mL\/min), Doppler indices as portal congestion index (CI<\/jats:styled-content>), liver vascular index, hepatic artery and superior mesenteric artery (SMA<\/jats:styled-content>) pulsatility and resistive indices (PI<\/jats:styled-content> and RI<\/jats:styled-content>), were performed before and after PSE<\/jats:styled-content>. In our study, 69 of 95 patients were males (72.6%) and 26 females (27.3%). Chronic hepatitis C<\/jats:styled-content> virus infection was the main cause of cirrhosis (81.1%). PSE<\/jats:styled-content> failed technically in six patients (6.3%). After PSE<\/jats:styled-content>, both CSA<\/jats:styled-content> and CI<\/jats:styled-content> significantly decreased (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.05 and <0.01). The portal vein velocity significantly increased (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.01). The portal flow volume (892.4\u00a0\u00b1\u00a0151\u00a0mL\/min) did not show significant changes. The hepatic artery RI<\/jats:styled-content> and PI<\/jats:styled-content> showed a steady increase that became significant 7\u00a0days post\u2010PSE<\/jats:styled-content> (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.05). The RI<\/jats:styled-content> and PI<\/jats:styled-content> of SMA<\/jats:styled-content> increased significantly after 7\u00a0days of PSE<\/jats:styled-content> (p\u00a0<\u00a0<\/jats:italic>0.05). PSE<\/jats:styled-content> has an immediate portal decompression effect in patients with portal hypertension without reduction in portal flow. This effect on portal pressure should be investigated in future studies as a potential tool for management of acute variceal bleeding when other medical procedures fail.<\/jats:p>","DOI":"10.1111\/apm.12470","type":"journal-article","created":{"date-parts":[[2015,11,8]],"date-time":"2015-11-08T19:13:26Z","timestamp":1447010006000},"page":"1032-1039","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Portal and splanchnic hemodynamics after partial\u00a0splenic embolization in cirrhotic patients with hypersplenism"],"prefix":"10.1111","volume":"123","author":[{"given":"Ahmed Z.","family":"Helaly","sequence":"first","affiliation":[{"name":"Internal Medicine Department Alexandria Faculty of Medicine Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Al\u2010Warraky","sequence":"additional","affiliation":[{"name":"Department of Radiology National Liver Institute Menoufiya University Shebeen El kom Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gasser I.","family":"El\u2010Azab","sequence":"additional","affiliation":[{"name":"Department of Hepatology National Liver Institute Menoufiya University Shebeen El kom Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A. 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