{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:28:46Z","timestamp":1791217726610,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T00:00:00Z","timestamp":1451260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007119","name":"Yasuj University of Medical Sciences","doi-asserted-by":"publisher","award":["23\u20102\u2010451"],"award-info":[{"award-number":["23\u20102\u2010451"]}],"id":[{"id":"10.13039\/501100007119","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>Methicilin resistance <jats:italic>Staphylococcus aureus<\/jats:italic> (<jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content>) infections are the major challenges in hospitals, especially in the burn units. The use of molecular typing methods is essential for tracking the spread of <jats:italic>S. aureus<\/jats:italic> infection and epidemiological investigations. The aim of this study was to find the profile of the spa types and also the prevalence of each <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content><jats:italic>mec<\/jats:italic> type of <jats:italic>S. aureus<\/jats:italic> strains in a central burn hospital in southwest of Iran. A total of 81 non\u2010duplicate <jats:italic>S. aureus<\/jats:italic> were isolated from burn patients between April 2011 and February 2012. The susceptibility of the isolates against 13 different antibiotics was tested by disk agar diffusion (<jats:styled-content style=\"fixed-case\">DAD<\/jats:styled-content>) method. <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> strains were identified by amplification of <jats:italic>mec<\/jats:italic>A gene. Multiplex\u2010polymerase chain reaction (<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>) technique was used to determine the <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content><jats:italic>mec<\/jats:italic> types of <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> strains and all the <jats:italic>S. aureus<\/jats:italic> isolates were typed by spa typing method. Detection of <jats:italic>mec<\/jats:italic>A gene showed that 70 (86.4%) of the isolates were <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content>. The highest rate of resistance was observed for penicillin (97.5%) and erythromycin (77.8%). None of the isolates were resistant to vancomycin. Sixty\u2010seven of the 70 <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> isolates harbored only <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content><jats:italic>mec<\/jats:italic> type <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> and three untypeable isolates. Five different <jats:italic>spa<\/jats:italic> types were detected. The most common <jats:italic>spa<\/jats:italic> types were t037 (42.5%) and t631 (34.5%) and were only found in <jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> isolates. Only <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content><jats:italic>mec<\/jats:italic> type <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> was found in burn patients which emphasizes the <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content> origin of these strains. Only five different spa types identified in this study are in accordance with one <jats:styled-content style=\"fixed-case\">SCC<\/jats:styled-content><jats:italic>mec<\/jats:italic> type which indicates that a limited number of bacterial colons are circulated in the burn unit in this hospital.<\/jats:p>","DOI":"10.1111\/apm.12493","type":"journal-article","created":{"date-parts":[[2015,12,28]],"date-time":"2015-12-28T05:29:08Z","timestamp":1451280548000},"page":"221-228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["High frequency of multidrug\u2010resistant <i>Staphylococcus aureus<\/i> with <scp>SCC<\/scp><i>mec<\/i> type <scp>III<\/scp> and <i>Spa<\/i> types t037 and t631 isolated from burn patients in southwest of Iran"],"prefix":"10.1111","volume":"124","author":[{"given":"Najmeh","family":"Parhizgari","sequence":"first","affiliation":[{"name":"Department of Virology School of Public Health Tehran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Sajjad","family":"Khoramrooz","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Research Center Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Ali Asghar","family":"Malek Hosseini","sequence":"additional","affiliation":[{"name":"Student Research Committee Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Marashifard","sequence":"additional","affiliation":[{"name":"Student Research Committee Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahboobeh","family":"Yazdanpanah","sequence":"additional","affiliation":[{"name":"Student Research Committee Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Emaneini","sequence":"additional","affiliation":[{"name":"Department of Microbiology School of Medicine Tehran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzaneh","family":"Gharibpour","sequence":"additional","affiliation":[{"name":"School of veterinary Medicine Shiraz University Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Mirzaii","sequence":"additional","affiliation":[{"name":"Department of Microbiology School of Medicine Shahrood University of Medical Sciences Shahrood Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davood","family":"Darban\u2010Sarokhalil","sequence":"additional","affiliation":[{"name":"Department of Microbiology School of Medicine Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Moein","sequence":"additional","affiliation":[{"name":"Student Research Committee Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmood","family":"Naraki","sequence":"additional","affiliation":[{"name":"Social Determinants of Health Research Center Yasuj University of Medical Sciences Yasuj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00044067-200208000-00005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2008.03861.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/138920307782411428"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2014.01.024"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2012.07.007"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00275-07"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.3.1001-1012.2006"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01689-12"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcp.2012.04.002"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-214"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.11.3556-3563.1999"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0702.010236"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-008-0463-0"},{"key":"e_1_2_7_15_1","first-page":"367","volume-title":"Text Book of Diagnostic Microbiology","author":"Harrison LS","year":"2007"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1556\/AMicr.58.2011.2.4"},{"key":"e_1_2_7_17_1","volume-title":"Performance standards for antimicrobial susceptibility testing. 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