{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:06:01Z","timestamp":1721174761049},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,2]],"date-time":"2016-11-02T00:00:00Z","timestamp":1478044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>The retroperitoneal space is a potential space extending from lumbar to the pelvic region, behind the peritoneum. It encloses many vital organs like adrenals, kidneys, ureters, pancreas, aorta and its branches, inferior vena cava and its tributaries and many lymph nodes along with loose connective tissue and fat. The literature regarding role of fine needle aspiration cytology (<jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content>) for diagnosis of retroperitoneal lesions as a whole, is exceedingly limited. The present study was conducted to elucidate the spectrum of retroperitoneal lesions and to determine the diagnostic accuracy of fine needle aspiration cytology, presenting to a tertiary care referral centre. A total of 389 aspirates from retroperitoneal lesions were reviewed for clinical and radiological details. The smears were studied for the cytological diagnosis. Cytological\u2013histological correlation was assessed and the causes for discordant diagnoses were determined. The patients\u2019 age ranged from 1 to 88 years. There were 234 (60.2%) males and 155 (39.8%) females. In 61 (15.7%) aspirations, the yield was inadequate for reporting and 328 were satisfactory. About 113 (29.0%) aspirates were from pancreatic masses alone, 97 (24.9%) from the retroperitoneal lymph nodes, 70 (17.9%) from the kidneys, 45 (11.5%) from the adrenals, 41 (10.5%) from the retroperitoneal soft tissues and 23 (5.9%) from retroperitoneal segments of the gut. There were 249 (64.0%) neoplastic lesions and 79 (20.3%) non\u2010neoplastic lesions, the ratio being 3.1:1. Eight (2.0%) aspirates were reported as suspicious for malignancy, and 5 (1.2%) aspirates were reported as neoplastic but could not be categorized as benign or malignant. Of the neoplastic lesions, malignant neoplasms (n = 216; 87.1%) were much more common than the benign (n = 20; 8.0%), the ratio being 10.8:1. Of all the satisfactory aspirates, subsequent histopathology was available only in 33\/327 (10%) cases. A positive correlation between cytological and histological diagnosis was observed in 27\/33 (81.8%) cases. We believe <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content> is a useful method for an early, rapid, minimally invasive and reliable pre\u2010operative diagnosis for retroperitoneal lesions and can often obviate the need for open surgical biopsy.<\/jats:p>","DOI":"10.1111\/apm.12627","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T05:01:22Z","timestamp":1478149282000},"page":"16-23","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Fine needle aspiration in retroperitoneal lesions"],"prefix":"10.1111","volume":"125","author":[{"given":"Parikshaa","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arvind","family":"Rajwanshi","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raje","family":"Nijhawan","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radhika","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalini","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma Nahar","family":"Saikia","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pranab","family":"Dey","sequence":"additional","affiliation":[{"name":"Department of Cytology and Gynaecological Pathology Postgraduate Institute of Medical Education and Research Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,2]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Aspiration Cytology","author":"DeMay RM"},{"key":"e_1_2_7_3_1","first-page":"2251","volume-title":"Rosai and Ackerman's Surgical Pathology","author":"Rosai J","year":"2004"},{"key":"e_1_2_7_4_1","first-page":"161","article-title":"Retroperitoneal masses: different clinical scenarios","volume":"20","author":"Murtaza B","year":"2008","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-57-673-43"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/028418518102200607"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4132\/jptm.2015.01.28"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.76943"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.130629"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.42090"},{"key":"e_1_2_7_11_1","first-page":"368","article-title":"Ultrasound\u2010guided percutaneous fine needle aspiration biopsy of abdominal and retroperitoneal masses. Accuracy of cytology in the diagnosis of malignancy, cytologic tumor typing and use of antibodies to intermediate filaments in selected cases","volume":"28","author":"Droese M","year":"1984","journal-title":"Acta Cytol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.59394"},{"key":"e_1_2_7_13_1","first-page":"99","article-title":"Ultrasound guided percutaneous fine needle aspiration biopsy (FNAB) of intraabdominal and retroperitoneal masses","volume":"8","author":"Jan GM","year":"1989","journal-title":"Indian J Gastroenterol"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.107511"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326539"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2000"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.01.039"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5851.133723"}],"container-title":["APMIS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapm.12627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapm.12627","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apm.12627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:31:40Z","timestamp":1696379500000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apm.12627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,2]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/apm.12627"],"URL":"https:\/\/doi.org\/10.1111\/apm.12627","archive":["Portico"],"relation":{},"ISSN":["0903-4641","1600-0463"],"issn-type":[{"value":"0903-4641","type":"print"},{"value":"1600-0463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,2]]},"assertion":[{"value":"2016-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}