{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:25:08Z","timestamp":1781652308090,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001424","name":"American Liver Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001424","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>In a primary care study of urinary tract infections (<jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>s) performed 2008 in Uppsala County, Sweden, 43% of the patients were culture negative. In order to investigate the background to the observed overdiagnosis of <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>, study invitations were sent to the previously included patients. A total of 256 patients (88% women) approved to participate. Patient charts and recorded laboratory data were reviewed. Two or more of the cardinal symptoms were reported in 53% of the women and in 19% of the men. A dipstick test was performed in 93% of the consultations. The highest positive predicted values in women had a positive nitrite test (95%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 87; 99) and dysuria in combination with urgency (81%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 72; 88). Seventy\u2010one percent of the women who fulfilled the symptom criteria received an antibiotic prescription directly, 87% of these had a positive culture. The drug of choice was pivmecillinam for women (51%) and quinolones (50%) for men. The treatment duration was too long for the women; 68% were treated for \u22657 days. In conclusion, the adherence to national guidelines\/recommendations was inadequate. To reduce the selection of multiresistant bacteria, an improvement of the use of diagnostic criteria\/tools and antibiotic drugs in primary care is necessary.<\/jats:p>","DOI":"10.1111\/apm.12718","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T08:40:37Z","timestamp":1496738437000},"page":"816-821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Inadequate adherence to Swedish guidelines for uncomplicated lower urinary tract infections among adults in general practice"],"prefix":"10.1111","volume":"125","author":[{"given":"Heidi","family":"Lindb\u00e4ck","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Section\u00a0of Clinical Microbiology Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Lindb\u00e4ck","sequence":"additional","affiliation":[{"name":"Uppsala Clinical Research Center Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5sa","family":"Melhus","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Section\u00a0of Clinical Microbiology Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmh720"},{"key":"e_1_2_6_3_1","first-page":"752","article-title":"Urinary tract infections in adult general practice patients","volume":"52","author":"Hummers\u2010Pradier E","year":"2002","journal-title":"Br J Gen Pract"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.20.2701"},{"key":"e_1_2_6_5_1","first-page":"361","article-title":"The diagnosis of urinary tract infection: a systematic review","volume":"107","author":"Schmiemann G","year":"2010","journal-title":"Dtsch \u00c4rztebl Int"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm108"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mda.2003.9"},{"key":"e_1_2_6_8_1","first-page":"635","article-title":"Management of urinary tract infection in general practice: a cost\u2010effectiveness analysis","volume":"50","author":"Fenwick EA","year":"2000","journal-title":"Br J Gen Pract"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c346"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.5.600"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl368"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp10X514747"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl082"},{"key":"e_1_2_6_14_1","unstructured":"Information fr\u00e5n L\u00e4kemedelsverket.Behandling av nedre urinv\u00e4gsinfektion hos kvinnor.2007;18:8\u201343. 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