{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:43:02Z","timestamp":1784544182763,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T00:00:00Z","timestamp":1505433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["DEC\u20102012\/05\/B\/NZ7\/02880"],"award-info":[{"award-number":["DEC\u20102012\/05\/B\/NZ7\/02880"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p><jats:italic>Acinetobacter baumannii<\/jats:italic> cause opportunistic nosocomial infections and is often multidrug resistant. It has ability to form biofilm. The possession of drug resistance mechanism and ability of biofilm formation seems to be the different way to enhancement of viability in stressful environment. In this study, we evaluate relation between these two factors. The biofilm formation was investigated in M63 medium with casein in microtiter plates, and the drug susceptibility was performed by disk diffusion methods. We found that 80\u201398% strains formed a biofilm. Strains showing sensitivity to amikacin and tobramycin from <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> produced more biofilm than strains showing resistance to these antibiotics. Ceftazidime\u2010sensitive strains formed a smaller biofilm than resistant. The logistic regression shows association between drug resistance and strains originating from <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>. In case of ceftazidime, strong biofilm formation and descending from <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> reduced the likelihood of drug sensitivity. For other drugs such as aminoglycosides, fluoroquinolones, trimethoprim\/sulfamethoxazole, and tetracycline, we found opposite relation (but it was not statistically significance). However, generally it seems that strong biofilm producers from <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>s are often more susceptible to antibiotics. This situation can be explained by the fact that bacteria protected in biofilm do not need mechanisms responsible for resistance of planktonic cells.<\/jats:p>","DOI":"10.1111\/apm.12739","type":"journal-article","created":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T08:22:38Z","timestamp":1505463758000},"page":"1017-1026","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["<i>Acinetobacter baumannii<\/i> isolated from hospital\u2010acquired infection: biofilm production and drug susceptibility"],"prefix":"10.1111","volume":"125","author":[{"given":"Pawe\u0142","family":"Krzy\u015bciak","sequence":"first","affiliation":[{"name":"Department of Mycology Jagiellonian University Medical College Krakow Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Chmielarczyk","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Microbial Ecology and Parasitology 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