{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T11:27:28Z","timestamp":1771932448903,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Hydrophilic polymer is used on multiple endovascular devices to decrease friction between these devices and vessel walls. Although it can prevent medical device\u2010related complications, hydrophilic polymer emboli (<jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content>) has recently been established as a potentially fatal iatrogenic phenomenon. <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content> can cause tissue injury in numerous sites, including the brain, heart, lung, skin, and intestines. Most <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content> reports have been from Europe and the USA. Therefore, we investigated the frequency, site distribution, and degree of tissue injury of <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content> in 227 Japanese autopsy cases. <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content> was noted in 3.1% (7\/227 cases), and was only found in the lung or heart. There were no cases with tissue injury, such as vasculopathy, ischemia or infarction, associated with <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content>. This is the first series study of <jats:styled-content style=\"fixed-case\">HPE<\/jats:styled-content> in Japanese autopsy cases. Unlike in reports from Europe and <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> HPE<\/jats:styled-content> was only seen in the lung or heart and did not injure the surrounding tissue.<\/jats:p>","DOI":"10.1111\/apm.12891","type":"journal-article","created":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T04:24:29Z","timestamp":1539663869000},"page":"838-841","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Clinicopathological features of hydrophilic polymer emboli in Japanese autopsy cases"],"prefix":"10.1111","volume":"126","author":[{"given":"Masashi","family":"Miyaoka","sequence":"first","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhito","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimasa","family":"Uekusa","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kanto Rosai Hospital Kawasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.74"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000765"},{"key":"e_1_2_5_4_1","first-page":"1886","article-title":"Foreign bodies in small arteries after use of an infusion microcatheter","volume":"18","author":"Barnwell SL","year":"1997","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2014.01.009"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2014.09.011"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12711"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.114.001816"}],"container-title":["APMIS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapm.12891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apm.12891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T00:38:47Z","timestamp":1694824727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apm.12891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,15]]},"references-count":7,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1111\/apm.12891"],"URL":"https:\/\/doi.org\/10.1111\/apm.12891","archive":["Portico"],"relation":{},"ISSN":["0903-4641","1600-0463"],"issn-type":[{"value":"0903-4641","type":"print"},{"value":"1600-0463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,15]]},"assertion":[{"value":"2018-07-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}