{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:55:52Z","timestamp":1762005352423},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T00:00:00Z","timestamp":1631145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Species (spp.) belonging to the genus Fusobacterium are anaerobic commensals colonizing the upper respiratory tract, the gastrointestinal tract, and the genitals. Infections with <jats:italic>Fusobacterium<\/jats:italic> spp. have been reported at many anatomical sites, including pneumonias and pleural empyemas; however, there are very few published cases of <jats:italic>Fusobacterium<\/jats:italic> spp. causing spondylodiscitis or fistulas. Bone infections with <jats:italic>Fusobacterium<\/jats:italic> can spread directly to surrounding muscular tissue or by hematogenous transmission to any other tissue including pleurae and lungs. Similarly, pleural infections can spread <jats:italic>Fusobacterium<\/jats:italic> spp. to any other tissue including fistulas and bone. Concomitant pleural empyema and spondylodiscitis are rare; however, there are a few published cases with concomitant disease, although none caused by <jats:italic>Fusobacterium<\/jats:italic> spp. A 77\u2010year\u2010old female patient was assessed using computed tomography (CT) scanning of the thorax and abdomen, as well as analyses of fluid drained from the region affected by the pleural empyema. A diagnosis of <jats:italic>Fusobacterium<\/jats:italic> empyema, fistula, bacteremia, and spondylodiscitis was made, and the patient\u2019s condition improved significantly after drainage of the pleural empyema and relevant long\u2010term antibiotic treatment. We describe the first confirmed case with concomitant infection with <jats:italic>Fusobacterium nucleatum<\/jats:italic> as spondylodiscitis and pleural empyema connected by a fistula.<\/jats:p>","DOI":"10.1111\/apm.13171","type":"journal-article","created":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T20:43:28Z","timestamp":1629578608000},"page":"626-630","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A unique case of <i>Fusobacterium nucleatum<\/i> spondylodiscitis communicating with a pleural empyema through a fistula"],"prefix":"10.1111","volume":"129","author":[{"given":"Barbara","family":"Bonnesen","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Zealand University Hospital Roskilde Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeesh","family":"Sivapalan","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Zealand 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