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The Bethesda category negative for intraepithelial lesion or malignancy (NILM) in the HPV\u2010negative cases given was present in 95.4%. Due to cytology other than NILM, 0.4% of cases were referred to colposcopy and 4.2% to the follow\u2010up in one year. In the follow\u2010up HPV negativity and NILM cytology was present in 88.3% of attended women. Cases other than HPV negative and NILM were referred to colposcopy. One biopsy\u2010proven histological HSIL was found in the first round and one in follow\u2010up screening. More comprehensive genotyping of HSIL cases revealed genotypes 69 and 11. Only two HPV test negative cases with histological HSIL were revealed forming 0.04% of quality control group. In both cases, HPV genotype not included in screening tests was found. According to the results, the primary HPV test with cytology triage is an efficient and specific method for cervical cancer screening despite of the fact that some non\u2010high\u2010risk genotypes are missed.<\/jats:p>","DOI":"10.1111\/apm.13265","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T07:48:39Z","timestamp":1658994519000},"page":"599-604","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cytohistological findings in <scp>HPV<\/scp>\u2010negative cases from\u00a0<scp>HPV<\/scp> primary screening programme: quality\u00a0assurance study"],"prefix":"10.1111","volume":"130","author":[{"given":"Saara","family":"Kares","sequence":"first","affiliation":[{"name":"Department of Pathology Fimlab Laboratories Ltd  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Kholov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Pathology Fimlab Laboratories Ltd  Tampere Finland"},{"name":"Faculty of Medicine and Health Technology Tampere University  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Tirkkonen","sequence":"additional","affiliation":[{"name":"Department of Pathology Fimlab Laboratories Ltd  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Risto","family":"Vuento","sequence":"additional","affiliation":[{"name":"Department of Microbiology Fimlab Laboratories Ltd  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Kujala","sequence":"additional","affiliation":[{"name":"Department of Pathology Fimlab Laboratories Ltd  Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(13)62218\u20107"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.08.053"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.09.006"},{"key":"e_1_2_7_5_1","unstructured":"Cervical Cancer Screening Current Guidelines Working Group set by the Finnish Medical Society Duodecim and The Finnish Colposcopic Society 2019. 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