{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:46:21Z","timestamp":1771911981584,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T00:00:00Z","timestamp":1662595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>The present study was conducted to compare the performance of patient self\u2010collected oral swab (OS) with healthcare worker (HCW)\u2010collected nasopharyngeal swab (NPS) for SARS\u2010CoV\u20102 detection by reverse transcription polymerase chain reaction (RT\u2010PCR) in real\u2010world setting. Paired OS and NPS were collected from 485 consecutive individuals presenting with symptoms of coronavirus disease\u201019 (COVID\u201019) or asymptomatic contacts of COVID\u201019 cases. Both specimens were processed for RT\u2010PCR and cycle threshold (Ct) value for each test was obtained. Positive percent agreement (PPA), negative percent agreement (NPA), overall percent agreement (OPA) and kappa were calculated for OS RT\u2010PCR compared with NPS RT\u2010PCR as reference. A total of 116\/485 (23.9%) participants were positive by NPS RT\u2010PCR. OS had PPA of 71.6%, NPA of 98.8%, OPA of 92.4% and kappa of 0.771. Almost all participants (483\/485, 99.6%) reported OS as a convenient and comfortable sample for SARS\u2010CoV\u20102 testing over NPS. All participants with Ct values &lt;25 and majority (90.8%) with Ct values &lt;30 were detected by OS. To conclude, OS self\u2010sampling was preferred in comparison with NPS due the ease and comfort during collection. The performance of OS RT\u2010PCR for SARS\u2010CoV\u20102 detection, however, was sub\u2010optimal in comparison with NPS RT\u2010PCR.<\/jats:p>","DOI":"10.1111\/apm.13266","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T03:58:31Z","timestamp":1659671911000},"page":"671-677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Diagnostic performance of patient self\u2010collected oral swab (tongue and cheek) in comparison with healthcare worker\u2010collected nasopharyngeal swab for severe acute respiratory syndrome coronavirus\u20102 detection"],"prefix":"10.1111","volume":"130","author":[{"given":"Arati","family":"Mane","sequence":"first","affiliation":[{"name":"ICMR\u2010National AIDS Research Institute  Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpa","family":"Jain","sequence":"additional","affiliation":[{"name":"Old Bhosari Hospital  Pune 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