{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:29:36Z","timestamp":1793104176675,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["APMIS"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Elimination of cervical cancer requires broad access to and participation in cervical screening. Self\u2010sampling has emerged as a robust technology that simplifies access; however, few self\u2010sampling devices are independently validated regarding sample quality. This study compares the quality of three self\u2010sampling devices: Evalyn (Rovers), currently used in Denmark, the FLOQSwab (Copan) and the modified FLOQSwab: SensiGrip. Women residing in the Capital Region of Denmark, accepting screening by self\u2010sampling, were offered a kit containing the following combinations of devices: (1) Evalyn, FLOQSwab, (2) Evalyn, SensiGrip or (3) FLOQSwab, SensiGrip. Returned kits were analyzed using the validated BD Onclarity HPV assay on the COR instrument (BD). A total of 1677 women participated. Sample quality was similar across devices, also when stratifying into age groups. Two hundred thirty\u2010two women (13.9%) tested positive for one or more oncogenic HPV types. Pairwise concordance analysis for each group showed an overall agreement between 93.5% and 95%. Analytical and diagnostic performance of samples collected by the three self\u2010sampling devices resulted in similar quality and HPV detection. Hence the sample quality is not a determinant in the choice of sampling device and focus on other factors such as cost, women's preference or size and weight can take precedence.<\/jats:p>","DOI":"10.1111\/apm.70109","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T11:25:51Z","timestamp":1764761151000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Large\u2010Scale Study Comparing Analytical and Diagnostic Quality of Three\n                    <scp>HPV<\/scp>\n                    Self\u2010Sampling Devices for At\u2010Home Cervical Cancer Screening"],"prefix":"10.1111","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1682-656X","authenticated-orcid":false,"given":"Alexander","family":"Arum","sequence":"first","affiliation":[{"name":"Department of Pathology, afs. 134, AHH\u2010Hvidovre Hospital Copenhagen University Hospital  Hvidovre 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Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Frandsen","sequence":"additional","affiliation":[{"name":"Department of Pathology, afs. 134, AHH\u2010Hvidovre Hospital Copenhagen University Hospital  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitte T\u00f8nnes","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Pathology, afs. 134, AHH\u2010Hvidovre Hospital Copenhagen University Hospital  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estrid","family":"Hogdall","sequence":"additional","affiliation":[{"name":"Department of Pathology, HGH\u2010Herlev Gentofte Hospital Copenhagen University Hospital  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4853-6747","authenticated-orcid":false,"given":"Jesper","family":"Bonde","sequence":"additional","affiliation":[{"name":"Department 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