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Blood in neonatal umbilical vein was collected immediately after delivery. Plasma <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>lu, <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content>, cortisol levels and rs4818 polymorphism in the genotypes and alleles of the two neonatal groups were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the <jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> group, 49 women (76.6%) experienced emotional abuse, 29 women (45.3%) experienced sexual abuse, 28 (43.8%) women experienced emotional abuse plus sexual abuse, and two women (3.1%) experienced emotional abuse plus physical abuse. We found that plasma <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>lu, <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content> and cortisol levels were higher in <jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates than in non\u2010<jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates. Furthermore, we observed a significantly positive correlation between maternal emotional abuse, sexual abuse and plasma levels of <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>lu, <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content> and cortisol in neonates. By genetic analysis we found a significant difference in rs4818<jats:styled-content style=\"fixed-case\">SNP<\/jats:styled-content> genotype and allele between the two neonatal groups. The ratios of <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> genotype and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content> allele were higher in <jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates than in non\u2010<jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates, and the ratios of <jats:styled-content style=\"fixed-case\">GG<\/jats:styled-content> genotype and <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content> allele were lower in <jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates than in non\u2010<jats:styled-content style=\"fixed-case\">DV<\/jats:styled-content> neonates. One\u2010way <jats:styled-content style=\"fixed-case\">ANOVA<\/jats:styled-content> test showed that <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content> level was lower in <jats:styled-content style=\"fixed-case\">CC<\/jats:styled-content> carriers than <jats:styled-content style=\"fixed-case\">CG<\/jats:styled-content> carriers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Domestic violence during pregnancy might be associated with increased plasma levels of glutamate, <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content>, cortisol and COMT gene polymorphism in neonates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/appy.12021","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T11:10:28Z","timestamp":1355224228000},"page":"2-10","source":"Crossref","is-referenced-by-count":12,"title":["Correlation of domestic violence during pregnancy with plasma amino\u2010acid neurotransmitter, cortisol 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