{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T16:05:45Z","timestamp":1726848345643},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia-Pacific Psychiatry"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The symptom profile of schizophrenia can vary between ethnic groups. We explored selected symptom variables previously reported to be characteristic of schizophrenia in the <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ban of <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>arawak in transethnic populations from <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndia, and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>arawak, <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>alaysia. We tested site differences to confirm previous research, and to explore implications of differences across populations for future investigations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recruited schizophrenia samples in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia (n\u2009=\u2009609), <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndia (n\u2009=\u2009310) and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>arawak (<jats:italic>n<\/jats:italic>\u2009=\u2009205) primarily for the purposes of genetic studies. We analyzed seven identified variables and their relationship to site using logistic regression, including: global delusions, bizarre delusions, thought broadcast\/insertion\/withdrawal delusions, global hallucinations, auditory hallucinations, disorganized behavior, and prodromal duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified a distinct symptom profile in our <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>arawak sample. Specifically, the <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ban exhibit: low frequency of thought broadcast\/insertion\/withdrawal delusions, high frequency of auditory hallucinations and disorganized behavior, with a comparatively short prodrome when compared with <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralian and <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndian populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Understanding between\u2010site variation in symptom profile may complement future transethnic genetic studies, and provide important clues as to the nature of differing schizophrenia expression across ethnically distinct groups. <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> comprehensive approach to subtyping schizophrenia is warranted, utilizing comprehensively ascertained transethnic samples to inform both schizophrenia genetics and nosology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/appy.12093","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T01:37:33Z","timestamp":1377221853000},"page":"36-44","source":"Crossref","is-referenced-by-count":2,"title":["Comparing schizophrenia symptoms in the <scp>I<\/scp>ban of <scp>S<\/scp>arawak with other populations to elucidate clinical heterogeneity"],"prefix":"10.1111","volume":"7","author":[{"given":"Duncan","family":"McLean","sequence":"first","affiliation":[{"name":"The Park \u2013 Centre for Mental Health Queensland Centre for Mental Health Research  Wacol QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Barrett","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Adelaide Royal Adelaide Hospital  Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Loa","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Adelaide Royal Adelaide Hospital  Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rangaswamy","family":"Thara","sequence":"additional","affiliation":[{"name":"Schizophrenia Research Foundation  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujit","family":"John","sequence":"additional","affiliation":[{"name":"Schizophrenia Research Foundation  Chennai Tamil Nadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"McGrath","sequence":"additional","affiliation":[{"name":"The Park \u2013 Centre for Mental Health Queensland Centre for Mental Health Research  Wacol QLD Australia"},{"name":"Queensland Brain Institute University of Queensland  Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jake","family":"Gratten","sequence":"additional","affiliation":[{"name":"The Park \u2013 Centre for Mental Health Queensland Centre for Mental Health Research  Wacol QLD Australia"},{"name":"Queensland Brain Institute University of Queensland  Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Mowry","sequence":"additional","affiliation":[{"name":"The Park \u2013 Centre for Mental Health Queensland Centre for Mental Health Research  Wacol QLD Australia"},{"name":"Queensland Brain Institute University of Queensland  Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,22]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_8_3_1","first-page":"959","article-title":"Ethnicity in epidemiological research. 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