{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:57:54Z","timestamp":1787313474900,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T00:00:00Z","timestamp":1433894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Fund for Science and Technology of Yongchuan District","award":["2011BE5010"],"award-info":[{"award-number":["2011BE5010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia-Pacific Psychiatry"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Postoperative delirium is a common clinical manifestation in geriatric patients, resulting in prolonged hospitalization and increased economic burden, in addition to higher morbidity and mortality rates. Therefore, identifying non\u2010obvious risk factors that contribute to the development of postoperative delirium in geriatric patients is crucial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From\n                      <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>\n                      anuary 2011 to\n                      <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>\n                      une 2013, 200 geriatric patients of over 65 years of age scheduled for orthopedic surgery were randomly selected and statistically analyzed with respect to the effects of the following 12 factors on postoperative delirium: sex, age, anesthesia type, surgical type (i.e. spine, hip replacement, and pelvic or femoral fracture repair), operative duration, intraoperative hypoxia, intraoperative hypercapnia, intraoperative hypotension, intraoperative blood loss, preoperative affective state, postoperative sleep disorders, and underlying disease (i.e. hypertension, coronary heart disease, diabetes, hyperlipidemia, and chronic bronchitis).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seven factors \u2013 age, anesthesia type, duration of operation, intraoperative hypercapnia, intraoperative hypotension, preoperative affective state, and postoperative sleep disorders \u2013 were found to be significantly differentiated, suggesting that these factors have an impact on the development of postoperative delirium. Sex, surgical type, intraoperative hypoxia, intraoperative blood loss (with 300\u2009ml as a cutoff value), and underlying disease were not directly related to the development of postoperative delirium.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Advanced age (&gt;70 years), the use of general anesthesia, longer surgical duration (&gt;3 hours), the presence of intraoperative hypercapnia and hypotension, the presence of preoperative affective dysfunction, and the presence of postoperative sleep disorders appear to be associated with the development of postoperative delirium in geriatric patients after orthopedic surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/appy.12193","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T09:04:07Z","timestamp":1434704647000},"page":"375-382","source":"Crossref","is-referenced-by-count":61,"title":["Risk factors contributing to postoperative delirium in geriatric patients postorthopedic surgery"],"prefix":"10.1111","volume":"7","author":[{"given":"Juan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Neurology Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaohai","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qunbo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Yongchuan Hospital Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,10]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"214","article-title":"Delirium in the elderly","volume":"60","author":"Alakkassery S.","year":"2012","journal-title":"J Med Liban"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-014-0141-2"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4067\/S0034-98872012000700003"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/10903127.2012.744785"},{"key":"e_1_2_8_6_1","first-page":"271","article-title":"Optimizing delirium prediction model in the management of hospitalized elderly patients","volume":"44","author":"Harimurti K.","year":"2012","journal-title":"Acta Med Indones"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/10903127.2012.729129"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra052321"},{"key":"e_1_2_8_9_1","first-page":"290","article-title":"Incidence and predictors for delirium in hospitalized elderly patients: a retrospective cohort study","volume":"44","author":"Isfandiaty R.","year":"2012","journal-title":"Acta Med Indones"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11825"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.regg.2012.05.001"},{"key":"e_1_2_8_12_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5770\/cgj.15.15","article-title":"A quality assurance study to assess the one\u2010day prevalence of delirium in elderly hospitalized patients","volume":"15","author":"McAiney C.A.","year":"2012","journal-title":"Can Geriatr J"},{"key":"e_1_2_8_13_1","first-page":"580481","article-title":"Isolated adrenocorticotropin deficiency associated with delirium and takotsubo cardiomyopathy","volume":"2012","author":"Murakami M.","year":"2012","journal-title":"Case Rep Endocrinol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"crossref","first-page":"717","DOI":"10.5664\/jcsm.2274","article-title":"\u201cMyxedema madness\u201d associated with newly diagnosed hypothyroidism and obstructive sleep apnea","volume":"8","author":"Neal J.M.","year":"2012","journal-title":"J Clin Sleep Med"},{"key":"e_1_2_8_15_1","first-page":"32","article-title":"Delirium in the intensive care unit: role of the critical care nurse in early detection and treatment","volume":"23","author":"Olson T.","year":"2012","journal-title":"Dynamics"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1024\/1661-8157\/a001147"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-2-51"},{"key":"e_1_2_8_18_1","first-page":"115","article-title":"The incidence and risk factors of postoperative delirium in elderly patients undergoing hip fracture operation","volume":"12","author":"Zhang C.H.","year":"2011","journal-title":"J Clin Anesthesiol"}],"container-title":["Asia-Pacific Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fappy.12193","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/appy.12193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T08:02:06Z","timestamp":1696492926000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/appy.12193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,10]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1111\/appy.12193"],"URL":"https:\/\/doi.org\/10.1111\/appy.12193","archive":["Portico"],"relation":{},"ISSN":["1758-5864","1758-5872"],"issn-type":[{"value":"1758-5864","type":"print"},{"value":"1758-5872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,10]]}}}