{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T07:36:02Z","timestamp":1793950562574,"version":"4.8.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T00:00:00Z","timestamp":1464220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Scientific Research Fund of Liaoning Science and Technology Agency, China","award":["2011225020"],"award-info":[{"award-number":["2011225020"]}]},{"name":"Independent Research Project Fund for Young Teachers of Yanshan University, China","award":["13LGB034"],"award-info":[{"award-number":["13LGB034"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia-Pacific Psychiatry"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective of this study was to evaluate levels and prevalence of anxiety in thyroid tumor patients awaiting surgery and diagnosis and to investigate whether significant differences existed in preoperative anxiety levels between patients with postoperative pathological diagnosis of benign thyroid tumors (BTT) or thyroid cancer (TC) in a Chinese\u2010Han population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five hundred and twenty\u2010nine patients awaiting surgery and diagnosis were chosen as the patient group, and 419 healthy Chinese were chosen as the control group. Anxiety levels were assessed by the State\u2010Trait Anxiety Inventory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cytological and histopathologic examinations showed BTT in 390 patients and TC in 139 patients. Moderate and high state\u2010anxiety prevalence were 63.3%, 66.9%, and 38.9%, and moderate and high trait\u2010anxiety prevalence were 53.6%, 56.1%, and 20.5% for BTT, TC, and healthy groups, respectively. There were significant differences in sample distributions between low and moderate\/high anxiety levels among the three groups (state\u2010anxiety, <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200960.95, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001; trait\u2010anxiety, <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u2009111.73, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The mean state\u2010anxiety scores were 41.02\u2009\u00b1\u20098.82, 42.71\u2009\u00b1\u20098.74, and 37.18\u2009\u00b1\u20097.46, and the mean trait\u2010anxiety scores were 41.91\u2009\u00b1\u20098.40, 42.69\u2009\u00b1\u20099.40, and 38.28\u2009\u00b1\u20096.30 for BTT, TC, and healthy groups, respectively. There were significant differences in the state\u2010anxiety (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200973.43, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and trait\u2010anxiety levels (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200972.21, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) among these three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This study has demonstrated that patients with BTT or TC have a high level of anxiety. The anxiety level of patients with TC is significantly higher than those with BTT. Our results indicate that anxiety may be a relative risk of thyroid tumor in Han\u2010Chinese. \u00a9 2016 John Wiley &amp; Sons Australia, Ltd<\/jats:p><\/jats:sec>","DOI":"10.1111\/appy.12245","type":"journal-article","created":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T05:01:24Z","timestamp":1464325284000},"source":"Crossref","is-referenced-by-count":12,"title":["Assessment of anxiety levels of patients awaiting surgery for suspected thyroid cancer: A case\u2010control study in a Chinese\u2010Han population"],"prefix":"10.1111","volume":"9","author":[{"given":"Yu","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Thyroid Surgery The First Affiliated Hospital of China Medical University  Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Ma","sequence":"additional","affiliation":[{"name":"Center for Mental Health Yanshan University  Qinhuangdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry The First Affiliated Hospital of China Medical University  Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiping","family":"Wang","sequence":"additional","affiliation":[{"name":"Clinical Nursing Section The First Affiliated Hospital of China Medical University  Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330300035030"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1997.7.613"},{"key":"e_1_2_9_4_1","first-page":"1801","article-title":"Assessment of general anxiety in patients with breast disease and breast cancer using the Spielberger STAI self evaluation test: a prospective 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