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In recent decades, postictal suppression on an electroencephalogram (EEG) has been considered a potential predictor of response to ECT. We aimed to investigate the direct association between postictal suppression and the therapeutic effects of ECT. In this systematic review, all articles in the field of the association between postictal suppression and the therapeutic effects of ECT published between 1990 and 2021 were identified. The full texts of these articles, which include clinical trials and retrospective and cross\u2010sectional studies, are available in scholarly research databases and search engines, including PubMed, Google Scholar, OVID, Web of Science, and Scopus. Of all retrieved articles, eight studies, including four retrospective cohort articles and four clinical trials, met the inclusion criteria for further analyses. The findings of this study showed a significant association between postictal suppression and the therapeutic efficacy of ECT. Factors such as electrode placement, tachycardia, type of anesthetic agent, and EEG amplitude were also directly related to postictal suppression and the efficacy of ECT. Postictal suppression on EEG can be considered a predictor of response to ECT. To increase the effectiveness of treatment with ECT and increase postictal suppression, factors including electrode placement, tachycardia, type of anesthesia, and EEG amplitude should be considered, which highlights the need for further research.<\/jats:p>","DOI":"10.1111\/appy.12544","type":"journal-article","created":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T21:32:05Z","timestamp":1692567125000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association between postictal suppression and the therapeutic effects of electroconvulsive therapy: A systematic review"],"prefix":"10.1111","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7886-1247","authenticated-orcid":false,"given":"Mahdie Ershad","family":"Langroudi","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine Kurdistan University of Medical Sciences  Sanandaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narges","family":"Shams\u2010Alizadeh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Neuroscience Research Center Kurdistan University of Medical Sciences  Sanandaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azad","family":"Maroufi","sequence":"additional","affiliation":[{"name":"Neurosciences Research Center, Research Institute for Health Development Kurdistan University of Medical Sciences  Sanandaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Rahmani","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Kurdistan University of Medical Sciences  Sanandaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Rahchamani","sequence":"additional","affiliation":[{"name":"School of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4190"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0b013e31807a2a94"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2010.05.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2012.04.021"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.7.664"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02189117"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2013.00094"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/15622975.2016.1252464"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-0327(98)00047-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4088\/jcp.v65n0406"},{"key":"e_1_2_9_12_1","first-page":"672","article-title":"Factors affecting electroconvulsive therapy ictal outcomes: Duration and postictal suppression","volume":"2019","author":"Ingram W. 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