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Results were correlated with clinical symptoms in different <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> Rome <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> subgroups. The effectiveness of a targeted saccharide\u2010reduced diet was assessed after 6\u20138\u00a0weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Intolerance prevalence across all <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content>s was 60% to fructose, 51% to lactose and 33% to both. Malabsorption occurred in 45%, 32% and 16% respectively. There were no differences in intolerance or malabsorption prevalence between <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> subgroups. <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> symptoms correlated with symptoms evoked during testing (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.35\u20130.61. <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001), but not with malabsorption. Non\u2010<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> symptoms occurred more commonly in patients with intolerances. Methane breath levels were not associated with constipation using several cut\u2010off thresholds. Adequate symptom relief was achieved in &gt;80% of intolerant patients, irrespective of malabsorption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fructose and lactose intolerances are common in <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> and associated with increased non\u2010<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> symptoms, but not with specific <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> subtypes. Symptoms experienced during breath testing, but not malabsorption, correlate with <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> symptoms. Effective symptom relief with dietary adaptation is not associated with malabsorption. Mechanisms relating to the generation of <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> and non\u2010<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> symptoms due to lactose and fructose in <jats:styled-content style=\"fixed-case\">FGID<\/jats:styled-content> need to be explored further.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.12306","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T01:20:38Z","timestamp":1365556838000},"page":"1074-1083","source":"Crossref","is-referenced-by-count":137,"title":["Fructose and lactose intolerance and malabsorption testing: the relationship with symptoms in functional gastrointestinal disorders"],"prefix":"10.1111","volume":"37","author":[{"given":"C. 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