{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T14:04:51Z","timestamp":1773497091015,"version":"3.50.1"},"reference-count":208,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":793,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1111\/apt.12381","type":"journal-article","created":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T01:08:44Z","timestamp":1372640924000},"page":"343-364","source":"Crossref","is-referenced-by-count":48,"title":["Review article: the management of autoimmune hepatitis beyond consensus guidelines"],"prefix":"10.1111","volume":"38","author":[{"given":"A. J.","family":"Czaja","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology; Mayo Clinic College of Medicine; Rochester; MN; USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,30]]},"reference":[{"key":"10.1111\/apt.12381-BIB0001|apt12381-cit-0001","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0168-8278(99)80297-9","article-title":"International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis","volume":"31","author":"Alvarez","year":"1999","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0002|apt12381-cit-0002","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/hep.22322","article-title":"Simplified criteria for the diagnosis of autoimmune hepatitis","volume":"48","author":"Hennes","year":"2008","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0003|apt12381-cit-0003","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1002\/hep.23584","article-title":"Practice Guidelines of the American Association for the Study of Liver Diseases. Diagnosis and management of autoimmune hepatitis","volume":"51","author":"Manns","year":"2010","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0004|apt12381-cit-0004","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1136\/gut.2010.235259","article-title":"British Society of Gastroenterology (BSG) guidelines for management of autoimmune hepatitis","volume":"60","author":"Gleeson","year":"2011","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0005|apt12381-cit-0005","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jhep.2010.09.002","article-title":"Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue","volume":"54","author":"Boberg","year":"2011","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0006|apt12381-cit-0006","doi-asserted-by":"crossref","first-page":"934","DOI":"10.3748\/wjg.v16.i8.934","article-title":"Difficult treatment decisions in autoimmune hepatitis","volume":"16","author":"Czaja","year":"2010","journal-title":"World J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0007|apt12381-cit-0007","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1053\/j.gastro.2010.04.053","article-title":"Advances in the diagnosis, pathogenesis and management of autoimmune hepatitis","volume":"139","author":"Czaja","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0008|apt12381-cit-0008","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1586\/egh.13.21","article-title":"Autoimmune hepatitis in diverse ethnic populations and geographical regions","volume":"7","author":"Czaja","year":"2013","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0009|apt12381-cit-0009","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jhep.2010.01.037","article-title":"Treatment options for autoimmune hepatitis: a systematic review of randomized controlled trials","volume":"53","author":"Lamers","year":"2010","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0010|apt12381-cit-0010","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cgh.2010.07.016","article-title":"Patients with typical laboratory features of autoimmune hepatitis rarely need a liver biopsy for diagnosis","volume":"9","author":"Bjornsson","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0011|apt12381-cit-0011","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S1542-3565(04)00246-0","article-title":"Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis","volume":"2","author":"Kessler","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0012|apt12381-cit-0012","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1053\/gast.1997.v113.pm9247489","article-title":"A novel histological lesion in glucocorticoid-responsive chronic hepatitis","volume":"113","author":"Pratt","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0013|apt12381-cit-0013","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/hep.24080","article-title":"Autoimmune acute liver failure: proposed clinical and histological criteria","volume":"53","author":"Stravitz","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0014|apt12381-cit-0014","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1053\/jhep.2001.27562","article-title":"Autoimmune hepatitis with incidental histologic features of bile duct injury","volume":"34","author":"Czaja","year":"2001","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0015|apt12381-cit-0015","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1478-3231.2004.0924.x","article-title":"Diagnostic and therapeutic implications of bile duct injury in autoimmune hepatitis","volume":"24","author":"Czaja","year":"2004","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0016|apt12381-cit-0016","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00535-008-2254-x","article-title":"Precise histological evaluation of liver biopsy specimen is indispensable for diagnosis and treatment of acute-onset autoimmune hepatitis","volume":"43","author":"Fujiwara","year":"2008","journal-title":"J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0017|apt12381-cit-0017","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1002\/hep.24481","article-title":"The use of liver biopsy evaluation in discrimination of idiopathic autoimmune hepatitis versus drug-induced liver injury","volume":"54","author":"Suzuki","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0018|apt12381-cit-0018","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.clinre.2011.08.011","article-title":"Liver biopsy is a superior diagnostic method in some patients showing the typical laboratory features of autoimmune hepatitis","volume":"36","author":"Efe","year":"2012","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0019|apt12381-cit-0019","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s10620-012-2445-4","article-title":"Acute and acute severe (fulminant) autoimmune hepatitis","volume":"58","author":"Czaja","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0020|apt12381-cit-0020","first-page":"297","article-title":"Steroid therapy in fulminant hepatic failure secondary to autoimmune hepatitis","volume":"17","author":"Viruet","year":"1998","journal-title":"P R Health Sci J"},{"key":"10.1111\/apt.12381-BIB0021|apt12381-cit-0021","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1007\/s00535-010-0316-3","article-title":"Clinicopathological features of severe and fulminant forms of autoimmune hepatitis","volume":"46","author":"Yasui","year":"2011","journal-title":"J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0022|apt12381-cit-0022","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S1386-6346(01)00109-7","article-title":"Clinical characteristics of autoimmune hepatitis with histological features of acute hepatitis","volume":"21","author":"Abe","year":"2001","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0023|apt12381-cit-0023","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S1089-3261(02)00022-3","article-title":"The role of histologic evaluation in the diagnosis and management of autoimmune hepatitis and its variants","volume":"6","author":"Carpenter","year":"2002","journal-title":"Clin Liver Dis"},{"key":"10.1111\/apt.12381-BIB0024|apt12381-cit-0024","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1872-034X.2011.00892.x","article-title":"Importance of computed tomography imaging features for the diagnosis of autoimmune acute liver failure","volume":"42","author":"Yasui","year":"2012","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0025|apt12381-cit-0025","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/0016-5085(88)90503-3","article-title":"Features reflective of early prognosis in corticosteroid-treated severe autoimmune chronic active hepatitis","volume":"95","author":"Czaja","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0026|apt12381-cit-0026","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1002\/hep.24141","article-title":"Early predictors of corticosteroid treatment failure in icteric presentations of autoimmune hepatitis","volume":"53","author":"Yeoman","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0027|apt12381-cit-0027","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S1386-6346(02)00274-7","article-title":"Clinicopathological features of acute-onset autoimmune hepatitis","volume":"25","author":"Okano","year":"2003","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0028|apt12381-cit-0028","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1872-034X.2007.00125.x","article-title":"Clinical features of Japanese type 1 autoimmune hepatitis patients with zone III necrosis","volume":"37","author":"Miyake","year":"2007","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0029|apt12381-cit-0029","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1016\/0016-5085(93)91081-R","article-title":"Sensitivity, specificity, and predictability of biopsy interpretations in chronic hepatitis","volume":"105","author":"Czaja","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0030|apt12381-cit-0030","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1111\/j.1572-0241.2002.06052.x","article-title":"Acute autoimmune hepatitis presenting with centrizonal liver disease: case report and review of the literature","volume":"97","author":"Singh","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0031|apt12381-cit-0031","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/lt.21036","article-title":"Usefulness of corticosteroids for the treatment of severe and fulminant forms of autoimmune hepatitis","volume":"13","author":"Ichai","year":"2007","journal-title":"Liver Transpl"},{"key":"10.1111\/apt.12381-BIB0032|apt12381-cit-0032","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1600-0676.1984.tb00914.x","article-title":"Manifestations of nonsuppurative cholangitis in chronic hepatobiliary diseases: morphologic spectrum, clinical correlations and terminology","volume":"4","author":"Ludwig","year":"1984","journal-title":"Liver"},{"key":"10.1111\/apt.12381-BIB0033|apt12381-cit-0033","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1053\/jhep.2000.7878","article-title":"Autoimmune cholangitis within the spectrum of autoimmune liver disease","volume":"31","author":"Czaja","year":"2000","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0034|apt12381-cit-0034","first-page":"326","article-title":"The overlap syndromes of autoimmune hepatitis","volume":"58","author":"Czaja","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0035|apt12381-cit-0035","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1478-3231.2005.01088.x","article-title":"An unusual form of autoimmune hepatitis in young Somalian men","volume":"25","author":"D'Souza","year":"2005","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0036|apt12381-cit-0036","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/0016-5085(92)91518-9","article-title":"Frequency and significance of antibodies to liver\/kidney microsome type 1 in adults with chronic active hepatitis","volume":"103","author":"Czaja","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0037|apt12381-cit-0037","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1046\/j.1440-1746.2001.02602.x","article-title":"Autoimmune hepatitis in the Indian subcontinent: 7 years experience","volume":"16","author":"Gupta","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0038|apt12381-cit-0038","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1136\/gut.51.2.259","article-title":"Establishment of standardised SLA\/LP immunoassays: specificity for autoimmune hepatitis, worldwide occurrence, and clinical characteristics","volume":"51","author":"Baeres","year":"2002","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0039|apt12381-cit-0039","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1007\/s00535-011-0421-y","article-title":"Present status of autoimmune hepatitis in Japan: a nationwide survey","volume":"46","author":"Abe","year":"2011","journal-title":"J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0040|apt12381-cit-0040","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0168-8278(02)00182-4","article-title":"Clinical distinctions and pathogenic implications of type 1 autoimmune hepatitis in Brazil and the United States","volume":"37","author":"Czaja","year":"2002","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0041|apt12381-cit-0041","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1136\/gut.50.5.713","article-title":"Characteristics of autoimmune hepatitis in patients who are not of European Caucasoid ethnic origin","volume":"50","author":"Zolfino","year":"2002","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0042|apt12381-cit-0042","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1478-3231.2008.01887.x","article-title":"Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis","volume":"29","author":"Radha","year":"2009","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0043|apt12381-cit-0043","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s12072-010-9217-z","article-title":"Predictors of outcome in acute-on-chronic liver failure in children","volume":"5","author":"Lal","year":"2011","journal-title":"Hepatol Int"},{"key":"10.1111\/apt.12381-BIB0044|apt12381-cit-0044","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1053\/jhep.2001.22131","article-title":"Autoimmune hepatitis\/sclerosing cholangitis overlap syndrome in childhood: a 16-year prospective study","volume":"33","author":"Gregorio","year":"2001","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0045|apt12381-cit-0045","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.1111\/j.1572-0241.2001.05272.x","article-title":"Autoimmune hepatitis in African Americans: presenting features and response to therapy","volume":"96","author":"Lim","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0046|apt12381-cit-0046","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1002\/hep.21884","article-title":"The impact of ethnicity on the natural history of autoimmune hepatitis","volume":"46","author":"Verma","year":"2007","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0047|apt12381-cit-0047","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/MCG.0b013e318228b781","article-title":"The impact of race\/ethnicity on the clinical epidemiology of autoimmune hepatitis","volume":"46","author":"Wong","year":"2012","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0048|apt12381-cit-0048","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.cgh.2011.04.027","article-title":"Chronic liver disease in the Hispanic population of the United States","volume":"9","author":"Carrion","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0049|apt12381-cit-0049","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1002\/hep.510300611","article-title":"Pediatric and adult forms of type I autoimmune hepatitis in Argentina: evidence for differential genetic predisposition","volume":"30","author":"Pando","year":"1999","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0050|apt12381-cit-0050","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s12072-009-9155-9","article-title":"Efficacy of ursodeoxycholic acid for Japanese patients with autoimmune hepatitis","volume":"3","author":"Miyake","year":"2009","journal-title":"Hepatol Int"},{"key":"10.1111\/apt.12381-BIB0051|apt12381-cit-0051","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/hep.22906","article-title":"AASLD Practice Guidelines. Primary biliary cirrhosis","volume":"50","author":"Lindor","year":"2009","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0052|apt12381-cit-0052","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/hep.23294","article-title":"Diagnosis and management of primary sclerosing cholangitis","volume":"51","author":"Chapman","year":"2010","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0053|apt12381-cit-0053","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1007\/s10620-011-1611-4","article-title":"Drug-induced autoimmune-like hepatitis","volume":"56","author":"Czaja","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0054|apt12381-cit-0054","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1002\/hep.23588","article-title":"Drug-induced autoimmune hepatitis: clinical characteristics and prognosis","volume":"51","author":"Bjornsson","year":"2010","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0055|apt12381-cit-0055","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1053\/gast.1996.v110.pm8608895","article-title":"Prognosis of histological cirrhosis in type 1 autoimmune hepatitis","volume":"110","author":"Roberts","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0056|apt12381-cit-0056","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/hep.1840030510","article-title":"Relapse following treatment withdrawal in patients with autoimmune chronic active hepatitis","volume":"3","author":"Hegarty","year":"1983","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0057|apt12381-cit-0057","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1478-3231.2007.01444.x","article-title":"Consequences of treatment withdrawal in type 1 autoimmune hepatitis","volume":"27","author":"Montano-Loza","year":"2007","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0058|apt12381-cit-0058","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1002\/hep.23577","article-title":"Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method","volume":"51","author":"Rockey","year":"2010","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0059|apt12381-cit-0059","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jhep.2010.12.041","article-title":"Recurrent drug-induced liver injury (DILI) with different drugs in the Spanish Registry: the dilemma of the relationship to autoimmune hepatitis","volume":"55","author":"Lucena","year":"2011","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0060|apt12381-cit-0060","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jhep.2009.04.009","article-title":"EASL Clinical Practice Guidelines: management of cholestatic liver diseases","volume":"51","author":"Beuers","year":"2009","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0061|apt12381-cit-0061","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/hep.510280203","article-title":"Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome: clinical features and response to therapy","volume":"28","author":"Chazouilleres","year":"1998","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0062|apt12381-cit-0062","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.cgh.2010.03.004","article-title":"Paris criteria are effective in diagnosis of primary biliary cirrhosis and autoimmune hepatitis overlap syndrome","volume":"8","author":"Kuiper","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0063|apt12381-cit-0063","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0168-8278(92)90178-R","article-title":"Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis","volume":"14","author":"Perdigoto","year":"1992","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0064|apt12381-cit-0064","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1002\/hep.22073","article-title":"Prevalence of sclerosing cholangitis in adults with autoimmune hepatitis: evaluating the role of routine magnetic resonance imaging","volume":"47","author":"Abdalian","year":"2008","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0065|apt12381-cit-0065","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1111\/j.1572-0241.2000.01999.x","article-title":"Variant forms of cholestatic diseases involving small bile ducts in adults","volume":"95","author":"Kim","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0066|apt12381-cit-0066","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1053\/jhep.2002.33202","article-title":"Small-duct primary sclerosing cholangitis: a long-term follow-up study","volume":"35","author":"Angulo","year":"2002","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0067|apt12381-cit-0067","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2249.2004.02332.x","article-title":"\u2018True\u2019 antimitochondrial antibody-negative primary biliary cirrhosis, low sensitivity of the routine assays, or both?","volume":"135","author":"Muratori","year":"2004","journal-title":"Clin Exp Immunol"},{"key":"10.1111\/apt.12381-BIB0068|apt12381-cit-0068","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0025-6196(11)63653-7","article-title":"Ludwig Symposium on biliary disorders. Autoimmune cholangitis: a unique entity?","volume":"73","author":"Sherlock","year":"1998","journal-title":"Mayo Clin Proc"},{"key":"10.1111\/apt.12381-BIB0069|apt12381-cit-0069","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/BF01296447","article-title":"Frequency and significance of antimitochondrial antibodies in severe chronic active hepatitis","volume":"31","author":"Kenny","year":"1986","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0070|apt12381-cit-0070","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/00008571-199208000-00002","article-title":"Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes","volume":"2","author":"Szumlanski","year":"1992","journal-title":"Pharmacogenetics"},{"key":"10.1111\/apt.12381-BIB0071|apt12381-cit-0071","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0009-9236(97)90152-1","article-title":"Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms","volume":"62","author":"Otterness","year":"1997","journal-title":"Clin Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0072|apt12381-cit-0072","first-page":"601","article-title":"Thiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyltransferase","volume":"29","author":"Weinshilboum","year":"2001","journal-title":"Drug Metab Dispos"},{"key":"10.1111\/apt.12381-BIB0073|apt12381-cit-0073","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/j.1552-4604.1990.tb03606.x","article-title":"Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients","volume":"30","author":"Chan","year":"1990","journal-title":"J Clin Pharmacol"},{"key":"10.1111\/apt.12381-BIB0074|apt12381-cit-0074","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0162-3109(00)00186-7","article-title":"Immunosuppressive drugs: the first 50 years and a glance forward","volume":"47","author":"Allison","year":"2000","journal-title":"Immunopharmacology"},{"key":"10.1111\/apt.12381-BIB0075|apt12381-cit-0075","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S1542-3565(04)00344-1","article-title":"Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety","volume":"2","author":"Dubinsky","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0076|apt12381-cit-0076","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1586\/17474124.2.1.23","article-title":"Azathioprine in inflammatory bowel disease: improved molecular insights and resulting clinical implications","volume":"2","author":"Atreya","year":"2008","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0077|apt12381-cit-0077","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1124\/jpet.104.074815","article-title":"Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines","volume":"312","author":"Thomas","year":"2005","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1111\/apt.12381-BIB0078|apt12381-cit-0078","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1172\/JCI16432","article-title":"CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes","volume":"111","author":"Tiede","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1111\/apt.12381-BIB0079|apt12381-cit-0079","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2036.2010.04499.x","article-title":"Increased proportion of CD16(+) NK cells in the colonic lamina propria of inflammatory bowel disease patients, but not after azathioprine treatment","volume":"33","author":"Steel","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0080|apt12381-cit-0080","first-page":"351","article-title":"Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis","volume":"23","author":"Ben","year":"1995","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0081|apt12381-cit-0081","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S1542-3565(04)00127-2","article-title":"Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease","volume":"2","author":"Cuffari","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0082|apt12381-cit-0082","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0168-8278(02)00214-3","article-title":"Thiopurine methyltransferase phenotype and genotype in relation to azathioprine therapy in autoimmune hepatitis","volume":"37","author":"Langley","year":"2002","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0083|apt12381-cit-0083","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.jhep.2006.05.011","article-title":"Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis","volume":"45","author":"Heneghan","year":"2006","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0084|apt12381-cit-0084","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1007\/s10620-006-9336-5","article-title":"Thiopurine methyltransferase deficiency and azathioprine intolerance in autoimmune hepatitis","volume":"51","author":"Czaja","year":"2006","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0085|apt12381-cit-0085","doi-asserted-by":"crossref","first-page":"716","DOI":"10.7326\/0003-4819-129-9-199811010-00007","article-title":"Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine","volume":"129","author":"Black","year":"1998","journal-title":"Ann Intern Med"},{"key":"10.1111\/apt.12381-BIB0086|apt12381-cit-0086","doi-asserted-by":"crossref","first-page":"608","DOI":"10.7326\/0003-4819-126-8-199704150-00003","article-title":"Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance","volume":"126","author":"Yates","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1111\/apt.12381-BIB0087|apt12381-cit-0087","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00228-008-0478-6","article-title":"Clinical pharmacology and pharmacogenetics of thiopurines","volume":"64","author":"Sahasranaman","year":"2008","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1111\/apt.12381-BIB0088|apt12381-cit-0088","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/clpt.1994.4","article-title":"Thiopurine methyltransferase activity in American white subjects and black subjects","volume":"55","author":"McLeod","year":"1994","journal-title":"Clin Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0089|apt12381-cit-0089","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/00007691-200206000-00005","article-title":"Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate","volume":"24","author":"Pettersson","year":"2002","journal-title":"Ther Drug Monit"},{"key":"10.1111\/apt.12381-BIB0090|apt12381-cit-0090","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1136\/gut.52.1.140","article-title":"Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine","volume":"52","author":"Kaskas","year":"2003","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0091|apt12381-cit-0091","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1053\/j.gastro.2004.09.061","article-title":"Use of laboratory testing to guide 6-mercaptopurine\/azathioprine therapy","volume":"127","author":"Lichtenstein","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0092|apt12381-cit-0092","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/00004836-200209000-00008","article-title":"Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease","volume":"35","author":"Regueiro","year":"2002","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0093|apt12381-cit-0093","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/FTD.0b013e3181dbd712","article-title":"Monitoring of azathioprine metabolites in pediatric patients with autoimmune hepatitis","volume":"32","author":"Nguyen","year":"2010","journal-title":"Ther Drug Monit"},{"key":"10.1111\/apt.12381-BIB0094|apt12381-cit-0094","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00004836-200207000-00016","article-title":"Prognosis of symptomatic versus asymptomatic autoimmune hepatitis: a study of 68 patients","volume":"35","author":"Kogan","year":"2002","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0095|apt12381-cit-0095","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/hep.20732","article-title":"Autoimmune hepatitis: effect of symptoms and cirrhosis on natural history and outcome","volume":"42","author":"Feld","year":"2005","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0096|apt12381-cit-0096","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1111\/j.1478-3231.2008.01904.x","article-title":"Features and consequences of untreated type 1 autoimmune hepatitis","volume":"29","author":"Czaja","year":"2009","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0097|apt12381-cit-0097","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/hep.1840040409","article-title":"Complete resolution of inflammatory activity following corticosteroid treatment of HBsAg-negative chronic active hepatitis","volume":"4","author":"Czaja","year":"1984","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0098|apt12381-cit-0098","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1053\/jhep.2002.32485","article-title":"Sustained remission after corticosteroid therapy for type 1 autoimmune hepatitis: a retrospective analysis","volume":"35","author":"Czaja","year":"2002","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0099|apt12381-cit-0099","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jhep.2012.09.009","article-title":"Relapse is almost universal after withdrawal of immunosuppressive medication in patients with autoimmune hepatitis in remission","volume":"58","author":"Gerven","year":"2013","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0100|apt12381-cit-0100","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1111\/j.1572-0241.2004.30457.x","article-title":"Factors predicting relapse and poor outcome in type I autoimmune hepatitis: role of cirrhosis development, patterns of transaminases during remission and plasma cell activity in the liver biopsy","volume":"99","author":"Verma","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0101|apt12381-cit-0101","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.jhep.2005.06.006","article-title":"Persistent normalization of serum alanine aminotransferase levels improves the prognosis of type 1 autoimmune hepatitis","volume":"43","author":"Miyake","year":"2005","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0102|apt12381-cit-0102","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1111\/j.1572-0241.2007.01153.x","article-title":"Improving the end point of corticosteroid therapy in type 1 autoimmune hepatitis to reduce the frequency of relapse","volume":"102","author":"Montano-Loza","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0103|apt12381-cit-0103","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/0016-5085(80)90866-5","article-title":"Clinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid-induced remission","volume":"78","author":"Czaja","year":"1980","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0104|apt12381-cit-0104","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/0016-5085(81)90126-8","article-title":"Laboratory assessment of severe chronic active liver disease during and after corticosteroid therapy: correlation of serum transaminase and gamma globulin levels with histologic features","volume":"80","author":"Czaja","year":"1981","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0105|apt12381-cit-0105","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/MCG.0b013e318154af74","article-title":"Serologic markers compared with liver biopsy for monitoring disease activity in autoimmune hepatitis","volume":"42","author":"Luth","year":"2008","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0106|apt12381-cit-0106","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1007\/s10620-010-1243-0","article-title":"Late relapse of type 1 autoimmune hepatitis after corticosteroid withdrawal","volume":"55","author":"Czaja","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0107|apt12381-cit-0107","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1007\/s10620-012-2151-2","article-title":"Advances in the current treatment of autoimmune hepatitis","volume":"57","author":"Czaja","year":"2012","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0108|apt12381-cit-0108","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S0168-8278(00)00095-7","article-title":"Duration of immunosuppressive therapy in autoimmune hepatitis","volume":"34","author":"Kanzler","year":"2001","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0109|apt12381-cit-0109","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/apt.12042","article-title":"Systematic review: managing suboptimal treatment responses in autoimmune hepatitis with conventional and nonstandard drugs","volume":"36","author":"Selvarajah","year":"2012","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0110|apt12381-cit-0110","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1056\/NEJM199510123331502","article-title":"Azathioprine for long-term maintenance of remission in autoimmune hepatitis","volume":"333","author":"Johnson","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12381-BIB0111|apt12381-cit-0111","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/hep.1840110621","article-title":"Low-dose corticosteroid therapy after multiple relapses of severe HBsAg-negative chronic active hepatitis","volume":"11","author":"Czaja","year":"1990","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0112|apt12381-cit-0112","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1002\/hep.21787","article-title":"Features associated with treatment failure in type 1 autoimmune hepatitis and predictive value of the model of end-stage liver disease","volume":"46","author":"Montano-Loza","year":"2007","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0113|apt12381-cit-0113","first-page":"221","article-title":"Failure of customary treatment in chronic active liver disease: causes and management","volume":"8","author":"Schalm","year":"1976","journal-title":"Ann Clin Res"},{"key":"10.1111\/apt.12381-BIB0114|apt12381-cit-0114","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1097\/01.mcg.0000177260.72692.e8","article-title":"Empiric therapy of autoimmune hepatitis with mycophenolate mofetil: comparison with conventional treatment for refractory disease","volume":"39","author":"Czaja","year":"2005","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0115|apt12381-cit-0115","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1155\/2012\/512132","article-title":"Autoimmune hepatitis: focusing on treatments other than steroids","volume":"26","author":"Czaja","year":"2012","journal-title":"Can J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0116|apt12381-cit-0116","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2174\/0929867043455576","article-title":"Inhibitors of the calcineurin\/NFAT pathway","volume":"11","author":"Martinez-Martinez","year":"2004","journal-title":"Curr Med Chem"},{"key":"10.1111\/apt.12381-BIB0117|apt12381-cit-0117","doi-asserted-by":"crossref","first-page":"463","DOI":"10.5694\/j.1326-5377.1985.tb123140.x","article-title":"Cyclosporin, a new treatment for autoimmune chronic active hepatitis","volume":"143","author":"Mistilis","year":"1985","journal-title":"Med J Aust"},{"key":"10.1111\/apt.12381-BIB0118|apt12381-cit-0118","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/0016-5085(87)90454-9","article-title":"Cyclosporine treatment of autoimmune chronic active hepatitis","volume":"93","author":"Hyams","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0119|apt12381-cit-0119","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1097\/00004836-199312000-00012","article-title":"A case of cyclosporine-sensitive, steroid-resistant, autoimmune chronic active hepatitis","volume":"17","author":"Person","year":"1993","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0120|apt12381-cit-0120","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/S0168-8278(05)80615-4","article-title":"Cyclosporine in the management of corticosteroid-resistant type I autoimmune chronic active hepatitis","volume":"21","author":"Sherman","year":"1994","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0121|apt12381-cit-0121","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/gut.36.3.459","article-title":"Cyclosporin in the treatment of corticosteroid resistant autoimmune chronic active hepatitis","volume":"36","author":"Jackson","year":"1995","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0122|apt12381-cit-0122","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1572-0241.1999.00807.x","article-title":"Cyclosporine therapy in patients with steroid resistant autoimmune hepatitis","volume":"94","author":"Fernandes","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0123|apt12381-cit-0123","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1023\/A:1010683817344","article-title":"Cyclosporin A is a promising alternative to corticosteroids in autoimmune hepatitis","volume":"46","author":"Malekzadeh","year":"2001","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0124|apt12381-cit-0124","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0022-3476(99)70339-2","article-title":"Efficacy of cyclosporin A in children with type 2 autoimmune hepatitis","volume":"135","author":"Debray","year":"1999","journal-title":"J Pediatr"},{"key":"10.1111\/apt.12381-BIB0125|apt12381-cit-0125","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0168-8278(99)80065-8","article-title":"Short-term cyclosporine induces a remission of autoimmune hepatitis in children","volume":"30","author":"Alvarez","year":"1999","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0126|apt12381-cit-0126","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/01.mpg.0000235975.75120.38","article-title":"Follow-up of children with autoimmune hepatitis treated with cyclosporine","volume":"43","author":"Cuarterolo","year":"2006","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1111\/apt.12381-BIB0127|apt12381-cit-0127","first-page":"771","article-title":"Tacrolimus: a potential new treatment for autoimmune chronic active hepatitis: results of an open-label preliminary trial","volume":"90","author":"Thiel","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0128|apt12381-cit-0128","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1097\/01.mcg.0000139050.67178.be","article-title":"Efficacy of tacrolimus in the treatment of steroid refractory autoimmune hepatitis","volume":"38","author":"Aqel","year":"2004","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0129|apt12381-cit-0129","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.3748\/wjg.v13.i23.3232","article-title":"Adel Hansen B. Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis","volume":"13","author":"Larsen","year":"2007","journal-title":"World J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0130|apt12381-cit-0130","first-page":"2811","article-title":"Cyclosporine-induced autoimmunity: critical role of autoregulation in the prevention of major histocompatibility class II-dependent autoaggression","volume":"25","author":"Hess","year":"1993","journal-title":"Transplant Proc"},{"issue":"Suppl. 3","key":"10.1111\/apt.12381-BIB0131|apt12381-cit-0131","doi-asserted-by":"crossref","first-page":"S462","DOI":"10.1111\/j.1872-034X.2007.00287.x","article-title":"De novo autoimmune hepatitis after liver transplantation","volume":"37","author":"Lohse","year":"2007","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0132|apt12381-cit-0132","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1007\/s10620-012-2179-3","article-title":"Diagnosis, pathogenesis, and treatment of autoimmune hepatitis after liver transplantation","volume":"57","author":"Czaja","year":"2012","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0133|apt12381-cit-0133","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1124\/mi.4.2.7","article-title":"Biochemical mechanisms of cyclosporine neurotoxicity","volume":"4","author":"Serkova","year":"2004","journal-title":"Mol Interv"},{"key":"10.1111\/apt.12381-BIB0134|apt12381-cit-0134","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000319032","article-title":"Tacrolimus-associated posterior reversible encephalopathy syndrome after solid organ transplantation","volume":"64","author":"Wu","year":"2010","journal-title":"Eur Neurol"},{"key":"10.1111\/apt.12381-BIB0135|apt12381-cit-0135","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0162-3109(00)00188-0","article-title":"Mycophenolate mofetil and its mechanisms of action","volume":"47","author":"Allison","year":"2000","journal-title":"Immunopharmacology"},{"issue":"Suppl. 1","key":"10.1111\/apt.12381-BIB0136|apt12381-cit-0136","doi-asserted-by":"crossref","first-page":"s2","DOI":"10.1177\/096120330501400102","article-title":"Mechanisms of action of mycophenolate mofetil","volume":"14","author":"Allison","year":"2005","journal-title":"Lupus"},{"key":"10.1111\/apt.12381-BIB0137|apt12381-cit-0137","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0168-8278(00)80271-8","article-title":"Mycophenolate mofetil for maintenance of remission in autoimmune hepatitis in patients resistant to or intolerant of azathioprine","volume":"33","author":"Richardson","year":"2000","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0138|apt12381-cit-0138","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1155\/2004\/504591","article-title":"Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory to standard therapy","volume":"18","author":"Devlin","year":"2004","journal-title":"Can J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0139|apt12381-cit-0139","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1478-3231.2005.01107.x","article-title":"Transplant immunosuppressive agents in non-transplant chronic autoimmune hepatitis: the Canadian association for the study of liver (CASL) experience with mycophenolate mofetil and tacrolimus","volume":"25","author":"Chatur","year":"2005","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0140|apt12381-cit-0140","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.cgh.2007.02.030","article-title":"Mycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapy","volume":"5","author":"Inductivo-Yu","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0141|apt12381-cit-0141","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1111\/j.1572-0241.2008.02180.x","article-title":"Mycophenolate mofetil as second line therapy in autoimmune hepatitis?","volume":"103","author":"Hennes","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0142|apt12381-cit-0142","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.cgh.2008.04.006","article-title":"A single center review of the use of mycophenolate mofetil in the treatment of autoimmune hepatitis","volume":"6","author":"Hlivko","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0143|apt12381-cit-0143","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jhep.2009.02.024","article-title":"Mycophenolate mofetil as rescue treatment for autoimmune liver disease in children: a 5-year follow-up","volume":"51","author":"Aw","year":"2009","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0144|apt12381-cit-0144","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1007\/s10620-008-0632-0","article-title":"Mycophenolate mofetil for autoimmune hepatitis: a single practice experience","volume":"54","author":"Wolf","year":"2009","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0145|apt12381-cit-0145","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1155\/2010\/891252","article-title":"Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory or intolerant to conventional therapy","volume":"24","author":"Sharzehi","year":"2010","journal-title":"Can J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0146|apt12381-cit-0146","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1365-2036.2011.04727.x","article-title":"The role of mycophenolate mofetil in the management of autoimmune hepatitis and overlap syndromes","volume":"34","author":"Baven-Pronk","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0147|apt12381-cit-0147","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1586\/egh.12.38","article-title":"Drug choices in autoimmune hepatitis: Part B - nonsteroids","volume":"6","author":"Czaja","year":"2012","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0148|apt12381-cit-0148","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jhep.2010.12.032","article-title":"Mycophenolate for the treatment of autoimmune hepatitis: prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naive patients","volume":"55","author":"Zachou","year":"2011","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0149|apt12381-cit-0149","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/S1701-2163(16)34622-9","article-title":"Prenatal exposure to mycophenolate mofetil: an updated estimate","volume":"32","author":"Klieger-Grossmann","year":"2010","journal-title":"J Obstet Gynaecol Can"},{"key":"10.1111\/apt.12381-BIB0150|apt12381-cit-0150","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1517\/14656566.7.2.145","article-title":"Cost-effectiveness of pharmacotherapy for autoimmune hepatitis","volume":"7","author":"Heneghan","year":"2006","journal-title":"Expert Opin Pharmacother"},{"key":"10.1111\/apt.12381-BIB0151|apt12381-cit-0151","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1586\/egh.12.40","article-title":"Drug choices in autoimmune hepatitis: part A - steroids","volume":"6","author":"Czaja","year":"2012","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0152|apt12381-cit-0152","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2165\/00003495-198428060-00001","article-title":"Budesonide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis","volume":"28","author":"Clissold","year":"1984","journal-title":"Drugs"},{"key":"10.1111\/apt.12381-BIB0153|apt12381-cit-0153","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1053\/j.gastro.2010.06.046","article-title":"Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis","volume":"139","author":"Manns","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0154|apt12381-cit-0154","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1365-2036.1994.tb00334.x","article-title":"Oral budesonide for treatment of autoimmune chronic active hepatitis","volume":"8","author":"Danielsson","year":"1994","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0155|apt12381-cit-0155","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/j.1478-3231.2005.01122.x","article-title":"Budesonide in previously untreated autoimmune hepatitis","volume":"25","author":"Wiegand","year":"2005","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0156|apt12381-cit-0156","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.3748\/wjg.v12.i9.1362","article-title":"Budesonide induces complete remission in autoimmune hepatitis","volume":"12","author":"Csepregi","year":"2006","journal-title":"World J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0157|apt12381-cit-0157","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1055\/s-2001-13708","article-title":"Long-term management and prognosis of autoimmune hepatitis (AIH): a single center experience","volume":"39","author":"Kanzler","year":"2001","journal-title":"Z Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0158|apt12381-cit-0158","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1590\/S0004-27302005000300008","article-title":"Antiproliferative and apoptotic potencies of glucocorticoids: nonconcordance with their antiinflammatory and immunosuppressive properties","volume":"49","author":"Longui","year":"2005","journal-title":"Arq Bras Endocrinol Metabol"},{"key":"10.1111\/apt.12381-BIB0159|apt12381-cit-0159","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.ijpharm.2011.02.062","article-title":"Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: comparison of prednisolone with budesonide","volume":"416","author":"Hofkens","year":"2011","journal-title":"Int J Pharm"},{"key":"10.1111\/apt.12381-BIB0160|apt12381-cit-0160","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.3748\/wjg.v9.i12.2681","article-title":"Side effects of budesonide in liver cirrhosis due to chronic autoimmune hepatitis: influence of hepatic metabolism versus portosystemic shunts on a patient complicated with HCC","volume":"9","author":"Geier","year":"2003","journal-title":"World J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0161|apt12381-cit-0161","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.autrev.2011.09.006","article-title":"Liver fibrosis may reduce the efficacy of budesonide in the treatment of autoimmune hepatitis and overlap syndrome","volume":"11","author":"Efe","year":"2012","journal-title":"Autoimmun Rev"},{"key":"10.1111\/apt.12381-BIB0162|apt12381-cit-0162","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1053\/gast.2000.0010000001","article-title":"Failure of budesonide in a pilot study of treatment-dependent autoimmune hepatitis","volume":"119","author":"Czaja","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0163|apt12381-cit-0163","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1002\/ajmg.a.32685","article-title":"Reviewing the evidence for mycophenolate mofetil as a new teratogen: case report and review of the literature","volume":"149A","author":"Anderka","year":"2009","journal-title":"Am J Med Genet A"},{"key":"10.1111\/apt.12381-BIB0164|apt12381-cit-0164","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jhep.2009.02.026","article-title":"Rapidity of treatment response and outcome in type 1 autoimmune hepatitis","volume":"51","author":"Czaja","year":"2009","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0165|apt12381-cit-0165","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/hep.21074","article-title":"Distinctive clinical phenotype and treatment outcome of type 1 autoimmune hepatitis in the elderly","volume":"43","author":"Czaja","year":"2006","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0166|apt12381-cit-0166","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1572-0241.2002.05479.x","article-title":"Antibodies to soluble liver antigen\/liver pancreas and HLA risk factors for type 1 autoimmune hepatitis","volume":"97","author":"Czaja","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0167|apt12381-cit-0167","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/liv.12022","article-title":"Antibodies to soluble liver antigen in patients with various liver diseases: a multicentre study","volume":"33","author":"Efe","year":"2013","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0168|apt12381-cit-0168","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1053\/jhep.2002.32092","article-title":"Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease","volume":"35","author":"Ma","year":"2002","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0169|apt12381-cit-0169","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1478-3231.2011.02502.x","article-title":"Prognostic implications of antibodies to Ro\/SSA and soluble liver antigen in type 1 autoimmune hepatitis","volume":"32","author":"Montano-Loza","year":"2012","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0170|apt12381-cit-0170","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0022-3476(86)80880-0","article-title":"Liver disease associated with anti-liver-kidney microsome antibody in children","volume":"108","author":"Maggiore","year":"1986","journal-title":"J Pediatr"},{"key":"10.1111\/apt.12381-BIB0171|apt12381-cit-0171","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/hep.1840070626","article-title":"Chronic active hepatitis associated with antiliver\/kidney microsome antibody type 1: a second type of \u201cautoimmune\u201d hepatitis","volume":"7","author":"Homberg","year":"1987","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0172|apt12381-cit-0172","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/j.1872-034X.2009.00510.x","article-title":"Clinical features of type 1 autoimmune hepatitis in adolescence and early adulthood","volume":"39","author":"Miyake","year":"2009","journal-title":"Hepatol Res"},{"key":"10.1111\/apt.12381-BIB0173|apt12381-cit-0173","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0002-9378(67)90503-0","article-title":"Azathioprine (Imuran) and pregnancy","volume":"97","author":"Rosenkrantz","year":"1967","journal-title":"Am J Obstet Gynecol"},{"key":"10.1111\/apt.12381-BIB0174|apt12381-cit-0174","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1111\/j.1572-0241.2006.00538.x","article-title":"Azathioprine use during pregnancy: unexpected intrauterine exposure to metabolites","volume":"101","author":"Boer","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0175|apt12381-cit-0175","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.semarthrit.2005.03.002","article-title":"Autoimmune hepatitis and pregnancy: a rheumatologist's dilemma","volume":"35","author":"Candia","year":"2005","journal-title":"Semin Arthritis Rheum"},{"key":"10.1111\/apt.12381-BIB0176|apt12381-cit-0176","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/gut.48.1.97","article-title":"Management and outcome of pregnancy in autoimmune hepatitis","volume":"48","author":"Heneghan","year":"2001","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0177|apt12381-cit-0177","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/gast.2003.50014","article-title":"The safety of 6-mercaptopurine for childbearing patients with inflammatory bowel disease: a retrospective cohort study","volume":"124","author":"Francella","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0178|apt12381-cit-0178","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1572-0241.2006.00479.x","article-title":"Pregnancy in autoimmune hepatitis: outcome and risk factors","volume":"101","author":"Schramm","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0179|apt12381-cit-0179","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1080\/00365520601155266","article-title":"Autoimmune hepatitis among fertile women: strategies during pregnancy and breastfeeding?","volume":"42","author":"Werner","year":"2007","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0180|apt12381-cit-0180","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1136\/gut.16.11.876","article-title":"Prednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine compared","volume":"16","author":"Summerskill","year":"1975","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0181|apt12381-cit-0181","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0016-5085(19)33223-8","article-title":"Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis","volume":"63","author":"Soloway","year":"1972","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0182|apt12381-cit-0182","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/j.1478-3231.2005.01141.x","article-title":"Autoimmune hepatitis type 1: safety and efficacy of prolonged medical therapy","volume":"25","author":"Seela","year":"2005","journal-title":"Liver Int"},{"key":"10.1111\/apt.12381-BIB0183|apt12381-cit-0183","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1126\/science.283.5406.1277","article-title":"A gender gap in autoimmunity","volume":"283","author":"Whitacre","year":"1999","journal-title":"Science"},{"key":"10.1111\/apt.12381-BIB0184|apt12381-cit-0184","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1111\/j.1572-0241.2002.07124.x","article-title":"Improvement of autoimmune hepatitis during pregnancy followed by flare-up after delivery","volume":"97","author":"Buchel","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0185|apt12381-cit-0185","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1002\/hep.1840080635","article-title":"Hepatocellular carcinoma in corticosteroid-treated severe autoimmune chronic active hepatitis","volume":"8","author":"Wang","year":"1988","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0186|apt12381-cit-0186","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1023\/A:1005638500236","article-title":"Hepatocellular carcinoma in autoimmune hepatitis","volume":"45","author":"Park","year":"2000","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0187|apt12381-cit-0187","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/hep.22432","article-title":"Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: implications for follow-up and screening","volume":"48","author":"Yeoman","year":"2008","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0188|apt12381-cit-0188","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1111\/j.1572-0241.2008.01922.x","article-title":"Predictive factors for hepatocellular carcinoma in type 1 autoimmune hepatitis","volume":"103","author":"Montano-Loza","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0189|apt12381-cit-0189","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1007\/s10620-010-1444-6","article-title":"Development of hepatocellular carcinoma in autoimmune hepatitis patients: a case series","volume":"56","author":"Wong","year":"2011","journal-title":"Dig Dis Sci"},{"key":"10.1111\/apt.12381-BIB0190|apt12381-cit-0190","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.cgh.2011.06.004","article-title":"Surveillance for hepatocellular carcinoma in patients with cirrhosis","volume":"10","author":"Yang","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0191|apt12381-cit-0191","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/hep.24199","article-title":"Management of hepatocellular carcinoma: an update","volume":"53","author":"Bruix","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0192|apt12381-cit-0192","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.jhep.2011.12.001","article-title":"EASL-EORTC clinical practice guidelines management of hepatocellular carcinoma","volume":"56","author":"EASL-EORTC","year":"2012","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0193|apt12381-cit-0193","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.48.2.251","article-title":"Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis","volume":"48","author":"Bolondi","year":"2001","journal-title":"Gut"},{"key":"10.1111\/apt.12381-BIB0194|apt12381-cit-0194","doi-asserted-by":"crossref","first-page":"99","DOI":"10.7863\/jum.2001.20.2.99","article-title":"Detection of hepatocellular carcinomas and dysplastic nodules in cirrhotic liver: accuracy of ultrasonography in transplant patients","volume":"20","author":"Kim","year":"2001","journal-title":"J Ultrasound Med"},{"key":"10.1111\/apt.12381-BIB0195|apt12381-cit-0195","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1365-2036.2009.04014.x","article-title":"Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis","volume":"30","author":"Singal","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12381-BIB0196|apt12381-cit-0196","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1053\/j.gastro.2009.05.014","article-title":"Alpha-fetoprotein for hepatocellular carcinoma diagnosis: the demise of a brilliant star","volume":"137","author":"Forner","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0197|apt12381-cit-0197","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.cgh.2012.12.046","article-title":"alpha-Fetoprotein in hepatocellular carcinoma surveillance: mend it but do not end it","volume":"11","author":"El-Serag","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12381-BIB0198|apt12381-cit-0198","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s12072-009-9145-y","article-title":"Ultrasound surveillance for early detection of hepatocellular carcinoma among patients with chronic hepatitis C","volume":"3","author":"Sato","year":"2009","journal-title":"Hepatol Int"},{"key":"10.1111\/apt.12381-BIB0199|apt12381-cit-0199","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.jhep.2009.11.026","article-title":"Serological surveillance for hepatocellular carcinoma: time to quit","volume":"52","author":"Sherman","year":"2010","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12381-BIB0200|apt12381-cit-0200","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1053\/j.gastro.2009.10.031","article-title":"Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma","volume":"138","author":"Lok","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12381-BIB0201|apt12381-cit-0201","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00432-004-0552-0","article-title":"Randomized controlled trial of screening for hepatocellular carcinoma","volume":"130","author":"Zhang","year":"2004","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1111\/apt.12381-BIB0202|apt12381-cit-0202","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1002\/hep.24033","article-title":"Alpha-fetoprotein should be included in the hepatocellular carcinoma surveillance guidelines of the American Association for the Study of Liver Diseases","volume":"53","author":"Marrero","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0203|apt12381-cit-0203","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/S1470-2045(09)70241-4","article-title":"Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009","volume":"10","author":"Poon","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1111\/apt.12381-BIB0204|apt12381-cit-0204","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1002\/hep.25869","article-title":"Screening for hepatocellular carcinoma: the rationale for the American Association for the Study of Liver Diseases recommendations","volume":"56","author":"Sherman","year":"2012","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0205|apt12381-cit-0205","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/MCG.0b013e3180381560","article-title":"Utilization of screening for hepatocellular carcinoma in the United States","volume":"41","author":"Davila","year":"2007","journal-title":"J Clini Gastroenterol"},{"key":"10.1111\/apt.12381-BIB0206|apt12381-cit-0206","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/hep.23615","article-title":"Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States","volume":"52","author":"Davila","year":"2010","journal-title":"Hepatology"},{"key":"10.1111\/apt.12381-BIB0207|apt12381-cit-0207","doi-asserted-by":"crossref","first-page":"85","DOI":"10.7326\/0003-4819-154-2-201101180-00006","article-title":"Utilization of surveillance for hepatocellular carcinoma among hepatitis C virus-infected veterans in the United States","volume":"154","author":"Davila","year":"2011","journal-title":"Ann Intern Med"},{"key":"10.1111\/apt.12381-BIB0208|apt12381-cit-0208","doi-asserted-by":"crossref","first-page":"387","DOI":"10.7326\/0003-4819-156-5-201203060-00012","article-title":"Screening for liver cancer: the rush to judgment","volume":"156","author":"Lederle","year":"2012","journal-title":"Ann Int Med"}],"container-title":["Alimentary Pharmacology & Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapt.12381","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/apt.12381\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T17:23:42Z","timestamp":1625419422000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.12381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,30]]},"references-count":208,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"URL":"https:\/\/doi.org\/10.1111\/apt.12381","relation":{},"ISSN":["0269-2813"],"issn-type":[{"value":"0269-2813","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6,30]]}}}