{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:29:02Z","timestamp":1773286142572,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":714,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Pharmacosmos"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1111\/apt.12493","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T15:06:03Z","timestamp":1444748763000},"page":"1109-1118","source":"Crossref","is-referenced-by-count":19,"title":["The management of iron deficiency in inflammatory bowel disease - an online tool developed by the RAND\/UCLA appropriateness method"],"prefix":"10.1111","volume":"38","author":[{"given":"W.","family":"Reinisch","sequence":"first","affiliation":[{"name":"Department Internal Medicine III; Medical University of Vienna; Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Chowers","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Rambam Health Care Campus; Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Danese","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Humanitas Clinical and Research Center; Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dignass","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Oncology, Infectious Diseases and Metabolism; Agaplesion Markus Hospital; Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gomoll\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Hospital Cl\u00ednico Universitario Lozano Blesa; CIBEREHD; Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Haagen Nielsen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Herlev Hospital; University of Copenhagen; Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. L.","family":"Lakatos","sequence":"additional","affiliation":[{"name":"1 Department of Medicine; Semmelweis University; Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. W.","family":"Lees","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Western General Hospital; Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Lindgren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; University Hospital Skane; University of Lund; Malm\u00f6 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lukas","sequence":"additional","affiliation":[{"name":"IBD Clinical and Research Centre; ISCARE Lighthouse and 1 Medical Faculty; Charles University; Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J.","family":"Mantzaris","sequence":"additional","affiliation":[{"name":"1 Department of Gastroenterology; Evangelismos Hospital; Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Michetti","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Lausanne University Medical Center; Lausanne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Moum","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Oslo University Hospital; University of Oslo; Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Peyrin-Biroulet","sequence":"additional","affiliation":[{"name":"Inserm, U954 and Department of Hepato-Gastroenterology; University Hospital of Nancy; Universit\u00e9 Henri Poincar\u00e9 1; Vandoeuvre-l\u00e8s-Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Toruner","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology; Ankara University School of Medicine; Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"van der Woude","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology; Erasmus University Medical Center; Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Weiss","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinical Immunology and Infectious Diseases; Medical University of Innsbruck; Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Stoevelaar","sequence":"additional","affiliation":[{"name":"Center for Decision Analysis and Support; Ismar Healthcare; Lier Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,17]]},"reference":[{"key":"10.1111\/apt.12493-BIB0001|apt12493-cit-0001","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1002\/ibd.20285","article-title":"Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases","volume":"13","author":"Gasche","year":"2007","journal-title":"Inflamm Bowel Dis"},{"key":"10.1111\/apt.12493-BIB0002|apt12493-cit-0002","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/j.1572-0241.2008.01846.x","article-title":"Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease","volume":"103","author":"Gisbert","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/apt.12493-BIB0003|apt12493-cit-0003","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/01.MIB.0000196646.64615.db","article-title":"Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients","volume":"12","author":"Wells","year":"2006","journal-title":"Inflamm Bowel Dis"},{"key":"10.1111\/apt.12493-BIB0004|apt12493-cit-0004","doi-asserted-by":"crossref","first-page":"782","DOI":"10.7326\/0003-4819-126-10-199705150-00006","article-title":"Intravenous iron and erythropoietin for anemia associated with Crohn disease. A randomized, controlled trial","volume":"126","author":"Gasche","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1111\/apt.12493-BIB0005|apt12493-cit-0005","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00054725-200005000-00013","article-title":"Anemia in IBD: the overlooked villain","volume":"6","author":"Gasche","year":"2000","journal-title":"Inflamm Bowel Dis"},{"key":"10.1111\/apt.12493-BIB0006|apt12493-cit-0006","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1136\/gut.2003.035758","article-title":"Iron, anaemia, and inflammatory bowel diseases","volume":"53","author":"Gasche","year":"2004","journal-title":"Gut"},{"key":"10.1111\/apt.12493-BIB0007|apt12493-cit-0007","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1002\/ibd.20925","article-title":"Oral and intravenous iron treatment in inflammatory bowel disease: hematological response and quality of life improvement","volume":"15","author":"Gisbert","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"10.1111\/apt.12493-BIB0008|apt12493-cit-0008","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1056\/NEJMoa0908355","article-title":"Ferric carboxymaltose in patients with heart failure and iron deficiency","volume":"361","author":"Anker","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12493-BIB0009|apt12493-cit-0009","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1503\/cmaj.110950","article-title":"Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial","volume":"184","author":"Vaucher","year":"2012","journal-title":"CMAJ"},{"key":"10.1111\/apt.12493-BIB0010|apt12493-cit-0010","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJMra041809","article-title":"Anemia of chronic disease","volume":"352","author":"Weiss","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12493-BIB0011|apt12493-cit-0011","doi-asserted-by":"crossref","first-page":"5277","DOI":"10.1182\/blood-2008-12-195651","article-title":"Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications","volume":"113","author":"Theurl","year":"2009","journal-title":"Blood"},{"key":"10.1111\/apt.12493-BIB0012|apt12493-cit-0012","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.crohns.2007.12.001","article-title":"European evidence-based Consensus on the management of ulcerative colitis: special situations","volume":"2","author":"Biancone","year":"2008","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0013|apt12493-cit-0013","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.crohns.2009.12.002","article-title":"The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: current management","volume":"4","author":"Dignass","year":"2010","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0014|apt12493-cit-0014","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1136\/gut.2010.224154","article-title":"Guidelines for the management of inflammatory bowel disease in adults","volume":"60","author":"Mowat","year":"2011","journal-title":"Gut"},{"key":"10.1111\/apt.12493-BIB0015|apt12493-cit-0015","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1136\/gut.2010.228874","article-title":"Guidelines for the management of iron deficiency anaemia","volume":"60","author":"Goddard","year":"2011","journal-title":"Gut"},{"key":"10.1111\/apt.12493-BIB0016|apt12493-cit-0016","doi-asserted-by":"crossref","first-page":"4666","DOI":"10.3748\/wjg.15.4666","article-title":"Intravenous iron in inflammatory bowel disease","volume":"15","author":"Mu\u00f1oz","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1111\/apt.12493-BIB0017|apt12493-cit-0017","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/nrgastro.2010.151","article-title":"Diagnosis and management of iron deficiency anemia in patients with IBD","volume":"7","author":"Stein","year":"2010","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1111\/apt.12493-BIB0018|apt12493-cit-0018","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1017\/S0266462300002774","article-title":"A method for the detailed assessment of the appropriateness of medical technologies","volume":"2","author":"Brook","year":"1986","journal-title":"Int J Technol Assess Health Care"},{"key":"10.1111\/apt.12493-BIB0019|apt12493-cit-0019","unstructured":"Fitch K Bernstein SJ Aguilar MS et\u00a0al The RAND\/UCLA appropriateness method user's manual http:\/\/www.rand.org\/pubs\/monograph_reports\/MR1269"},{"key":"10.1111\/apt.12493-BIB0020|apt12493-cit-0020","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1177\/0272989X04264212","article-title":"The appropriateness method","volume":"24","author":"Shekelle","year":"2004","journal-title":"Med Decis Making"},{"key":"10.1111\/apt.12493-BIB0021|apt12493-cit-0021","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1055\/s-0028-1119627","article-title":"Appropriateness of colonoscopy in Europe (EPAGE II). Chronic diarrhea and known inflammatory bowel disease","volume":"41","author":"Schussel\u00e9 Filliettaz","year":"2009","journal-title":"Endoscopy"},{"key":"10.1111\/apt.12493-BIB0022|apt12493-cit-0022","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.crohns.2009.09.002","article-title":"On the second European panel on the appropriateness of Crohn's disease therapy (EPACT-II)","volume":"3","author":"Dubois","year":"2009","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0023|apt12493-cit-0023","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.dld.2004.12.013","article-title":"Appropriateness of immunosuppressive drugs in inflammatory bowel diseases assessed by RAND method: Italian Group for IBD (IG-IBD) position statement","volume":"37","author":"Caprilli","year":"2005","journal-title":"Dig Liver Dis"},{"key":"10.1111\/apt.12493-BIB0024|apt12493-cit-0024","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.cgh.2010.04.023","article-title":"The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit all","volume":"8","author":"Melmed","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/apt.12493-BIB0025|apt12493-cit-0025","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/jama.2009.205","article-title":"Scientific evidence underlying the ACC\/AHA clinical practice guidelines","volume":"301","author":"Tricoci","year":"2009","journal-title":"JAMA"},{"key":"10.1111\/apt.12493-BIB0026|apt12493-cit-0026","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1056\/NEJM199806253382607","article-title":"The reproducibility of a method to identify the overuse and underuse of medical procedures","volume":"338","author":"Shekelle","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12493-BIB0027|apt12493-cit-0027","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/00005650-199909000-00009","article-title":"Reproducibility of measures of overuse of cataract surgery by three physician panels","volume":"37","author":"Tobacman","year":"1999","journal-title":"Med Care"},{"key":"10.1111\/apt.12493-BIB0028|apt12493-cit-0028","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archinte.166.2.220","article-title":"Health-related quality of life and appropriateness of knee or hip joint replacement","volume":"166","author":"Quintana","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1111\/apt.12493-BIB0029|apt12493-cit-0029","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1056\/NEJM200103013440906","article-title":"Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization","volume":"344","author":"Hemingway","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12493-BIB0030|apt12493-cit-0030","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.crohns.2012.07.031","article-title":"State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease?","volume":"7","author":"Reinisch","year":"2013","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0031|apt12493-cit-0031","doi-asserted-by":"crossref","first-page":"595970","DOI":"10.1155\/2012\/595970","article-title":"High prevalence but insufficient treatment of iron-deficiency anemia in patients with inflammatory bowel disease: results of a population-based cohort","volume":"2012","author":"Ott","year":"2012","journal-title":"Gastroenterol Res Pract"},{"key":"10.1111\/apt.12493-BIB0032|apt12493-cit-0032","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.crohns.2010.07.008","article-title":"Prevalence of anaemia in inflammatory bowel disease in Switzerland: a cross-sectional study in patients from private practices and university hospitals","volume":"4","author":"Voegtlin","year":"2010","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0033|apt12493-cit-0033","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1126\/science.1104742","article-title":"Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization","volume":"306","author":"Nemeth","year":"2004","journal-title":"Science"},{"key":"10.1111\/apt.12493-BIB0034|apt12493-cit-0034","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1053\/j.gastro.2011.06.005","article-title":"FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease","volume":"141","author":"Evstatiev","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12493-BIB0035|apt12493-cit-0035","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.crohns.2010.01.007","article-title":"The health care cost of intravenous iron treatment in IBD patients depends on the economic evaluation perspective","volume":"4","author":"Bager","year":"2010","journal-title":"J Crohns Colitis"},{"key":"10.1111\/apt.12493-BIB0036|apt12493-cit-0036","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3324\/haematol.2009.017046","article-title":"Pathogenesis and treatment of anemia in inflammatory bowel disease","volume":"95","author":"Weiss","year":"2010","journal-title":"Haematologica"},{"key":"10.1111\/apt.12493-BIB0037|apt12493-cit-0037","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3324\/haematol.2009.009985","article-title":"Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment","volume":"95","author":"Bergamaschi","year":"2010","journal-title":"Haematologica"}],"container-title":["Alimentary Pharmacology & Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapt.12493","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/apt.12493\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T16:32:16Z","timestamp":1625416336000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.12493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,17]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,11]]}},"URL":"https:\/\/doi.org\/10.1111\/apt.12493","archive":["Portico"],"relation":{},"ISSN":["0269-2813"],"issn-type":[{"value":"0269-2813","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9,17]]}}}