{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:24:23Z","timestamp":1788870263534,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T00:00:00Z","timestamp":1402272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Key Clinical Department in Ministry of Public Health, China","award":["303004269002"],"award-info":[{"award-number":["303004269002"]}]},{"name":"Scientific Project of Guangzhou, China","award":["2011YZ-00004"],"award-info":[{"award-number":["2011YZ-00004"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Magnetic resonance enterography (\n MRE<\/jats:styled-content>\n ) has been proposed as a non\u2010ionising alternative method to computed tomography enterography (\n CTE<\/jats:styled-content>\n ). Some studies have directly compared\n CTE<\/jats:styled-content>\n and\n MRE<\/jats:styled-content>\n in patients with small bowel Crohn's disease (\n CD<\/jats:styled-content>\n ) with variable results.\n <\/jats:p>\n <\/jats:sec>\n \n Aim<\/jats:title>\n To compare the overall diagnostic accuracy in assessing the activity of small bowel and complications.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n MEDLINE<\/jats:styled-content>\n ,\n EMBASE<\/jats:styled-content>\n and Cochrane databases were searched for studies on the accuracy of\n MRE<\/jats:styled-content>\n and\n CTE<\/jats:styled-content>\n , as compared with a pre\u2010defined reference standard. Pooled sensitivity, specificity, the weighted area under the curve (\n AUC<\/jats:styled-content>\n ), incremental yield (\n IY<\/jats:styled-content>\n ) and other diagnostic indices were evaluated.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 290\n CD<\/jats:styled-content>\n patients from six different studies were analysed. The pooled sensitivity and specificity for\n MRE<\/jats:styled-content>\n in detecting active small bowel\n CD<\/jats:styled-content>\n was 87.9% [95% confidence interval (\n CI<\/jats:styled-content>\n ), 81.8\u201392.5] and 81.2% (95%\n CI<\/jats:styled-content>\n : 71.9\u201388.4) respectively. The\n AUC<\/jats:styled-content>\n under the summary receiver\u2010operating characteristic (s\n ROC<\/jats:styled-content>\n ) of\n MRE<\/jats:styled-content>\n was 0.905 (SEM 0.03, standard error of the mean). Likewise, the pooled sensitivity and specificity of\n CTE<\/jats:styled-content>\n in detecting active small bowel\n CD<\/jats:styled-content>\n was 85.8% (95%\n CI<\/jats:styled-content>\n : 79.2\u201390.9) and 83.6% (95%\n CI<\/jats:styled-content>\n : 75.3\u201390.1) with the\n AUC<\/jats:styled-content>\n of 0.898. The\n AUC<\/jats:styled-content>\n of\n MRE<\/jats:styled-content>\n in detecting fistula, stenosis and abscess was 0.936, 0.931 and 0.996, respectively, compared to 0.963, 0.616 and 0.899 of\n CTE<\/jats:styled-content>\n . No statistically significant\n IY<\/jats:styled-content>\n for\n MRE<\/jats:styled-content>\n vs.\n CTE<\/jats:styled-content>\n was found (fixed model,\n P\u00a0<\/jats:italic>\n >\n \u00a0<\/jats:italic>\n 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Magnetic resonance enterography has a diagnostic effectiveness comparable to computed tomography enterography, thus may serve as a radiation\u2010free alternative for evaluation of patients with Crohn's disease.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/apt.12815","type":"journal-article","created":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T21:13:03Z","timestamp":1402348383000},"page":"134-146","source":"Crossref","is-referenced-by-count":129,"title":["Systematic review with meta\u2010analysis: magnetic resonance enterography vs. computed tomography enterography for evaluating disease activity in small bowel Crohn's disease"],"prefix":"10.1111","volume":"40","author":[{"given":"Y.","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.\u2010L.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.\u2010H.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"He","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.\u2010R.","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.\u2010P.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology The First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u2010H.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology First Affiliated Hospital of Sun Yat\u2010Sen University Guangzhou 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