{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T22:37:01Z","timestamp":1782772621951,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":355,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council of Taiwan","doi-asserted-by":"crossref","award":["NSC 99-2314-B-182A-009-MY3"],"award-info":[{"award-number":["NSC 99-2314-B-182A-009-MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1111\/apt.12953","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T05:46:27Z","timestamp":1410414387000},"page":"1056-1065","source":"Crossref","is-referenced-by-count":57,"title":["Scoring systems for 6-month mortality in critically ill cirrhotic patients: a prospective analysis of chronic liver failure - sequential organ failure assessment score (CLIF-SOFA)"],"prefix":"10.1111","volume":"40","author":[{"given":"H.-C.","family":"Pan","sequence":"first","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-C.","family":"Jenq","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-H.","family":"Tsai","sequence":"additional","affiliation":[{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"},{"name":"Division of Gastroenterology; Chang Gung Memorial Hospital; Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.-C.","family":"Fan","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-H.","family":"Chang","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-Y.","family":"Chang","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.-C.","family":"Tian","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-C.","family":"Hung","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-T.","family":"Fang","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.-W.","family":"Yang","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.-C.","family":"Chen","sequence":"additional","affiliation":[{"name":"Kidney Research Center; Department of Nephrology; Chang Gung Memorial Hospital; Taipei Taiwan"},{"name":"Chang Gung University College of Medicine; Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,11]]},"reference":[{"key":"10.1111\/apt.12953-BIB0001|apt12953-cit-0001","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1002\/hep.22605","article-title":"Acute kidney injury in cirrhosis","volume":"48","author":"Garcia-Tsao","year":"2008","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0002|apt12953-cit-0002","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1056\/NEJMra0809139","article-title":"Renal failure in cirrhosis","volume":"361","author":"Gin\u00e8s","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1111\/apt.12953-BIB0003|apt12953-cit-0003","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1007\/s00134-012-2523-2","article-title":"Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients","volume":"38","author":"O'Brien","year":"2012","journal-title":"Intensive Care Med"},{"key":"10.1111\/apt.12953-BIB0004|apt12953-cit-0004","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1002\/hep.1840080532","article-title":"Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis","volume":"8","author":"Schrier","year":"1988","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0005|apt12953-cit-0005","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1002\/hep.20993","article-title":"The hyperdynamic circulation of chronic liver diseases: from the patient to the molecule","volume":"43","author":"Iwakiri","year":"2006","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0006|apt12953-cit-0006","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1365-2036.2009.04175.x","article-title":"Review article: the current management of acute liver failure","volume":"31","author":"Craig","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0007|apt12953-cit-0007","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1111\/apt.12721","article-title":"Competing risks and prognostic stages of cirrhosis: a 25-year inception cohort study of 494 patients","volume":"39","author":"D'Amico","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0008|apt12953-cit-0008","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/apt.12133","article-title":"Review article: towards a considered and ethical approach to organ support in critically-ill patients with cirrhosis","volume":"37","author":"Berry","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0009|apt12953-cit-0009","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000078789","article-title":"Multiple organ system failure in critically ill cirrhotic patients - A comparison of two multiple organ dysfunction\/failure scoring systems","volume":"69","author":"Tsai","year":"2004","journal-title":"Digestion"},{"key":"10.1111\/apt.12953-BIB0010|apt12953-cit-0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5414\/CNP61111","article-title":"Comparison of the severity of illness scoring systems for critically ill cirrhotic patients with renal failure","volume":"61","author":"Chen","year":"2004","journal-title":"Clin Nephrol"},{"key":"10.1111\/apt.12953-BIB0011|apt12953-cit-0011","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1742-1241.2005.00634.x","article-title":"Prospective cohort study comparing sequential organ failure assessment and acute physiology, age, chronic health evaluation III scoring systems for hospital mortality prediction in critically ill cirrhotic patients","volume":"60","author":"Chen","year":"2006","journal-title":"Int J Clin Pract"},{"key":"10.1111\/apt.12953-BIB0012|apt12953-cit-0012","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1093\/ndt\/gfm914","article-title":"Outcome predictors and new score of critically ill cirrhotic patients with acute renal failure","volume":"23","author":"Fang","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1111\/apt.12953-BIB0013|apt12953-cit-0013","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1371\/journal.pone.0051094","article-title":"Risk models and scoring systems for predicting the prognosis in critically ill cirrhotic patients with acute kidney injury: a prospective validation study","volume":"7","author":"Pan","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/apt.12953-BIB0014|apt12953-cit-0014","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1136\/gut.2004.038679","article-title":"Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club","volume":"54","author":"Wong","year":"2005","journal-title":"Gut"},{"key":"10.1111\/apt.12953-BIB0015|apt12953-cit-0015","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/tri.12064","article-title":"Peripheral platelet count correlates with liver atrophy and predicts long-term mortality on the liver transplant waiting list","volume":"26","author":"Bleibel","year":"2013","journal-title":"Transpl Int"},{"key":"10.1111\/apt.12953-BIB0016|apt12953-cit-0016","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.clinre.2013.05.001","article-title":"Prognostic scores for cirrhotic patients admitted to an intensive care unit: which consequences for liver transplantation?","volume":"37","author":"Galbois","year":"2013","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1111\/apt.12953-BIB0017|apt12953-cit-0017","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1053\/j.gastro.2013.02.042","article-title":"Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis","volume":"144","author":"Moreau","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12953-BIB0018|apt12953-cit-0018","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3","article-title":"Index for rating diagnostic tests","volume":"3","author":"Youden","year":"1950","journal-title":"Cancer"},{"key":"10.1111\/apt.12953-BIB0019|apt12953-cit-0019","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1002\/hep.24622","article-title":"Intensive care of the patient with cirrhosis","volume":"54","author":"Olson","year":"2011","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0020|apt12953-cit-0020","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jhep.2013.11.012","article-title":"Outcome of patients with cirrhosis requiring mechanical ventilation in ICU","volume":"60","author":"Levesque","year":"2014","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12953-BIB0021|apt12953-cit-0021","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1053\/j.gastro.2010.06.019","article-title":"Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis","volume":"139","author":"Arvaniti","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12953-BIB0022|apt12953-cit-0022","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jcrc.2008.04.006","article-title":"Hemodynamics and metabolic studies on septic shock in patients with acute liver failure","volume":"23","author":"Tsai","year":"2008","journal-title":"J Crit Care"},{"key":"10.1111\/apt.12953-BIB0023|apt12953-cit-0023","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/apt.12653","article-title":"Review article: advances in the management of patients with cirrhosis and portal hypertension-related renal dysfunction","volume":"39","author":"Leithead","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0024|apt12953-cit-0024","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/apt.12797","article-title":"Prevalence and in-hospital mortality trends of infections among patients with cirrhosis: a nationwide study of hospitalised patients in the United States","volume":"40","author":"Singal","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0025|apt12953-cit-0025","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1053\/he.2000.5852","article-title":"A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts","volume":"31","author":"Malinchoc","year":"2000","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0026|apt12953-cit-0026","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jhep.2007.10.008","article-title":"Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy","volume":"48","author":"Abraldes","year":"2008","journal-title":"J Hepatol"},{"issue":"Suppl. 1","key":"10.1111\/apt.12953-BIB0027|apt12953-cit-0027","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1016\/S0168-8278(12)60003-8","article-title":"Management of critically-ill cirrhotic patients","volume":"56","author":"Gin\u00e8s","year":"2012","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12953-BIB0028|apt12953-cit-0028","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1097\/CCM.0b013e3181f3dea9","article-title":"Cirrhotic patients in the medical intensive care unit: early prognosis and long-term survival","volume":"38","author":"Das","year":"2010","journal-title":"Crit Care Med"},{"key":"10.1111\/apt.12953-BIB0029|apt12953-cit-0029","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1053\/jhep.2001.26522","article-title":"Short-term prognosis in critically ill patients with cirrhosis assessed by prognostic scoring systems","volume":"34","author":"Wehler","year":"2001","journal-title":"Hepatology"},{"key":"10.1111\/apt.12953-BIB0030|apt12953-cit-0030","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1365-2036.2010.04341.x","article-title":"Outcomes of critically ill patients with cirrhosis admitted to intensive care: an important perspective from the non-transplant setting","volume":"32","author":"Thomson","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0031|apt12953-cit-0031","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.jhep.2013.10.004","article-title":"Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF)","volume":"60","author":"Cordoba","year":"2014","journal-title":"J Hepatol"},{"key":"10.1111\/apt.12953-BIB0032|apt12953-cit-0032","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.mpmed.2011.07.008","article-title":"Hepatic encephalopathy","volume":"39","author":"Ryan","year":"2011","journal-title":"Medicine"},{"key":"10.1111\/apt.12953-BIB0033|apt12953-cit-0033","first-page":"1310","article-title":"Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis","volume":"56","author":"Salerno","year":"2007","journal-title":"Gut"},{"key":"10.1111\/apt.12953-BIB0034|apt12953-cit-0034","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2215\/CJN.03681106","article-title":"Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes","volume":"2","author":"Bagshaw","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1111\/apt.12953-BIB0035|apt12953-cit-0035","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1007\/s00134-007-0760-6","article-title":"RIFLE classification can predict short-term prognosis in critically ill cirrhotic patients","volume":"33","author":"Jenq","year":"2007","journal-title":"Intensive Care Med"},{"issue":"5","key":"10.1111\/apt.12953-BIB0036|apt12953-cit-0036","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/ki.2011.405","article-title":"Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury","volume":"81","author":"Bucaloiu","year":"2012","journal-title":"Kidney Int"},{"key":"10.1111\/apt.12953-BIB0037|apt12953-cit-0037","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/apt.12299","article-title":"Predicting the development of acute kidney injury in liver cirrhosis - an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers","volume":"37","author":"Slack","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/apt.12953-BIB0038|apt12953-cit-0038","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1097\/00003246-198807000-00005","article-title":"Prognosis of patients with cirrhosis and chronic liver disease admitted to the medical intensive care unit","volume":"16","author":"Shellman","year":"1988","journal-title":"Crit Care Med"},{"key":"10.1111\/apt.12953-BIB0039|apt12953-cit-0039","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/MCC.0000000000000067","article-title":"Advances in management and prognostication in critically ill cirrhotic patients","volume":"20","author":"Karvellas","year":"2014","journal-title":"Curr Opin Crit Care"},{"key":"10.1111\/apt.12953-BIB0040|apt12953-cit-0040","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1053\/j.gastro.2007.01.040","article-title":"Risk factors for mortality after surgery in patients with cirrhosis","volume":"132","author":"Teh","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1111\/apt.12953-BIB0041|apt12953-cit-0041","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.jhep.2012.06.026","article-title":"Acute-on chronic liver failure","volume":"57","author":"Jalan","year":"2012","journal-title":"J Hepatol"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapt.12953","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/apt.12953\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T16:29:42Z","timestamp":1625416182000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.12953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,11]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,11]]}},"URL":"https:\/\/doi.org\/10.1111\/apt.12953","relation":{},"ISSN":["0269-2813"],"issn-type":[{"value":"0269-2813","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9,11]]}}}