{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:25:11Z","timestamp":1790727911235,"version":"4.1.0"},"reference-count":134,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T00:00:00Z","timestamp":1437523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of diverticulosis and diverticular disease of the colon, including diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems. Treatment of patients with diverticulosis and DD is generally based on high\u2010fibre diet and antibiotics, respectively. However, new pathophysiological knowledge suggests that further treatment may be useful.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To review the current treatment of diverticulosis and diverticular disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A search of PubMed and Medline databases was performed to identify articles relevant to the management of diverticulosis and diverticular disease. Major international conferences were also reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two randomised controlled trials (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>) found the role of antibiotics in managing acute diverticulitis to be questionable, particularly in patients with no complicating comorbidities. One <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content> found mesalazine to be effective in preventing acute diverticulitis in patients with symptomatic uncomplicated diverticular disease. The role of rifaximin or mesalazine in preventing diverticulitis recurrence, based on the results of 1 and 4 <jats:styled-content style=\"fixed-case\">RCTs<\/jats:styled-content>, respectively, remains unclear. <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s found rifaximin and mesalazine to be effective in treating symptomatic uncomplicated diverticular disease. The use of probiotics in diverticular disease and in preventing acute diverticulitis occurrence\/recurrence appears promising but unconclusive. Finally, the role of fibre in treating diverticulosis remains unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Available evidence suggests that antibiotics have a role only in the treatment of complicated diverticulitis. It appears to be some evidence for a role for rifaximin and mesalazine in treating symptomatic uncomplicated diverticular disease. Finally, there is not currently adequate evidence to recommend any medical treatment for the prevention of diverticulitis recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.13322","type":"journal-article","created":{"date-parts":[[2015,7,23]],"date-time":"2015-07-23T03:05:57Z","timestamp":1437620757000},"page":"664-684","source":"Crossref","is-referenced-by-count":114,"title":["Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon"],"prefix":"10.1111","volume":"42","author":[{"given":"A.","family":"Tursi","sequence":"first","affiliation":[{"name":"Gastroenterology Service ASL BAT Andria BT Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Papa","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine and Gastroenterology Complesso Integrato \u201cColumbus\u201d Catholic University Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Danese","sequence":"additional","affiliation":[{"name":"IBD Unit IRCCS \u201cHumanitas\u201d Rozzano MI Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.194"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.04072.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0953-0673.2003.01720.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000124003.07433.ee"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/60.5.757"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.02121.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/1117-1936.169543","article-title":"Spectrum of colonoscopy findings in Ile\u2010Ife Nigeria","volume":"19","author":"Alatise OI","year":"2012","journal-title":"Niger Postgrad Med J"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.323"},{"key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0016-5085(19)35481-2","article-title":"The clinical significance of diverticulosis","volume":"35","author":"Boles JRRS","year":"1958","journal-title":"Gastroenterology"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2004.03.001"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2014.903922"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181952888"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01879.x"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-0161-2"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649901007"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01501.x"},{"key":"e_1_2_12_18_1","first-page":"258","article-title":"Gastroenterology diagnosis and treatment guidelines of diverticular disease of the colon. Clinical and diagnostic","volume":"73","author":"Hern\u00e1ndez\u2010Guerrero A","year":"2008","journal-title":"Rev Gastroenterol Mex"},{"key":"e_1_2_12_19_1","first-page":"C4453","article-title":"Danish national guidelines for treatment of diverticular disease","volume":"59","author":"Andersen JC","year":"2012","journal-title":"Dan Med J"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.2478\/pjs-2013-0045"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000367625"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640614547068"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.018093"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e31819ef79a"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1296-3"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000268"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01445.x"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.026112"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13583-0"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01308.x"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.04.006"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2007.01037.x"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)90313-N"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200309000-00011"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2011.01863.x"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-014-2162-3"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2012.05069.x"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.12.030"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/258164"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000232"},{"issue":"1","key":"e_1_2_12_41_1","first-page":"12","article-title":"Microscopic colitis as part of the natural history of diverticular disease","volume":"97","author":"Narayan R","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181dad979"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3180653ca2"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.02926.x"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302514a.119"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2012.01946.x"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335722"},{"key":"e_1_2_12_48_1","first-page":"12","article-title":"Detection of endoscopic and histological inflammation after an attack of colonic diverticulitis is associated with higher diverticulitis recurrence","volume":"22","author":"Tursi A","year":"2013","journal-title":"J Gastrointest Liver Dis"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-012-0194-8"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-008-0667-8"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1053\/bega.2002.0323"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i45.16858"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2882-2"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1236158"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07383.x"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04530.x"},{"key":"e_1_2_12_57_1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.15403\/jgld.2014.1121.tur","article-title":"The role of colonoscopy in managing diverticular disease of the colon","volume":"24","author":"Tursi A","year":"2015","journal-title":"J Gastrointestin Liver Dis"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.03.007"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.621"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-008-0536-5"},{"key":"e_1_2_12_61_1","first-page":"13","article-title":"Detection of endoscopic and histological inflammation after an attack of colonic diverticulitis is associated with higher diverticulitis recurrence","volume":"22","author":"Tursi A","year":"2013","journal-title":"J Gastrointestin Liver Dis"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.12.017"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12152"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0595-9"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000094"},{"key":"e_1_2_12_66_1","first-page":"247","article-title":"Role of fecal calprotectin in the diagnosis and treatment of segmental colitis associated with diverticulosis","volume":"57","author":"Tursi A","year":"2011","journal-title":"Minerva Gastroenterol Dietol"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.78"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000230"},{"key":"e_1_2_12_69_1","unstructured":"World Gastroenterology Organisation (WGO) Practice Guidelines.Diverticular disease 2007.http:\/\/www.worldgastroenterology.org\/assets\/downloads\/en\/pdf\/guidelines\/07_diverticular_diseasepdf 2007 (accessed 15 April 2008)."},{"key":"e_1_2_12_70_1","first-page":"261","article-title":"Gastroenterology diagnosis and treatment guidelines of diverticular disease of the colon. Treatment","volume":"73","author":"Char\u00faa\u2010Guindic L","year":"2008","journal-title":"Rev Gastroenterol Mex"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-011-1308-3"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)92112-2"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6273.1353"},{"key":"e_1_2_12_74_1","first-page":"157","article-title":"The placebo effect. Is it important in diverticular disease?","volume":"67","author":"Hodgson WJ","year":"1977","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.035"},{"key":"e_1_2_12_76_1","first-page":"365","article-title":"In vitro activity of rifaximin and rifampicin against some anaerobic bacteria","volume":"3","author":"Lamanna A","year":"1984","journal-title":"Chemioterapia"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.1995.tb00348.x"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0396-5"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04606.x"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.03342.x"},{"key":"e_1_2_12_81_1","first-page":"245","article-title":"Therapeutic and prophylactic role of mesalazine (5\u2010ASA) in symptomatic diverticular disease of the large intestine. 4\u00a0year follow\u2010up results","volume":"45","author":"Trespi E","year":"1999","journal-title":"Minerva Gastroenterol Dietol"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-2478-z"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000210092.77296.6d"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-9766-8"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9551-0"},{"key":"e_1_2_12_86_1","first-page":"916","article-title":"Mesalazine and\/or Lactobacillus casei in maintaining long\u2010term remission of symptomatic uncomplicated diverticular disease of the colon","volume":"55","author":"Tursi A","year":"2008","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12248"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12463"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1159\/000342079"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12596"},{"key":"e_1_2_12_91_1","first-page":"13","article-title":"Efficacy of Lactobacillus paracasei sub. paracasei F19 on abdominal symptoms in patients with symptomatic uncomplicated diverticular disease: a pilot study","volume":"57","author":"Annibale B","year":"2011","journal-title":"Minerva Gastroenterol Dietol"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i41.5918"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.06.020"},{"key":"e_1_2_12_94_1","first-page":"173","article-title":"High fibre diet in symptomatic diverticular disease of the colon","volume":"67","author":"Leahy AL","year":"1985","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4131"},{"key":"e_1_2_12_96_1","first-page":"452","article-title":"Efficacy of rifaximin on symptoms of uncomplicated diverticular disease of the colon: a pilot multicentre open trial. Diverticular Disease Study Group","volume":"24","author":"Papi C","year":"1992","journal-title":"Ital J Gastroenterol"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i2.264"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.120580"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000075"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02234169"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12057"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-010-0899-4"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-012-0847-0"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182965a11"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02609.x"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8688"},{"issue":"1","key":"e_1_2_12_107_1","first-page":"A2","article-title":"A randomized clinical trial of observational versus antibiotic treatment for a first episode of uncomplicated acute diverticulitis","volume":"2","author":"Daniels L","year":"2014","journal-title":"United Eur Gastroenterol J"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7723"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520802321204"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000219682.98158.11"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.8.907"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.09.006"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(02)80110-4"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31828003f6"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1722-9"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.07.004"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(13)60503-X"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(14)60663-6"},{"key":"e_1_2_12_119_1","unstructured":"GamanA. Teodorescu R GeorhescuEF AbagiuMT.Prophylactic effects of mesalamine in diverticular disease. Falk Symposium 178 2011 Abstract 13."},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0299-6"},{"key":"e_1_2_12_121_1","first-page":"149","article-title":"Acute recurrent diverticulitis is prevented by oral administration of a polybacterial lysate suspension","volume":"50","author":"Dughera L","year":"2004","journal-title":"Minerva Gastroenterol Dietol"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-008-9234-3"},{"key":"e_1_2_12_123_1","first-page":"804","article-title":"Current indications and role of surgery in the management of sigmoid diverticulitis","volume":"16","author":"Stocchi L","year":"2010","journal-title":"World J Gastroenterol"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966399"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-3257-0"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182a26bfd"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31823a43a1"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7602"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e31822899a2"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04782.x"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000294"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2014.987809"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-014-1884-0"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1159\/000366039"},{"key":"e_1_2_12_135_1","first-page":"e125","article-title":"Predictive value of the DICA classification on the outcome of diverticular disease of the colon","volume":"47","author":"Tursi A","year":"2015","journal-title":"Digest Liver Dis"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fapt.13322","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apt.13322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T22:21:08Z","timestamp":1695507668000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.13322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,22]]},"references-count":134,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1111\/apt.13322"],"URL":"https:\/\/doi.org\/10.1111\/apt.13322","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,22]]}}}