{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:51:14Z","timestamp":1793400674305,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T00:00:00Z","timestamp":1520812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["1T32DK101363"],"award-info":[{"award-number":["1T32DK101363"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK079902"],"award-info":[{"award-number":["R01DK079902"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oesophageal hypervigilance and anxiety can drive symptom experience in chronic oesophageal conditions, including gastro\u2010oesophageal reflux disease, achalasia and functional oesophageal disorders. To date, no validated self\u2010report measure exists to evaluate oesophageal hypervigilance and anxiety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      This study aims to develop a brief and reliable questionnaire assessing these constructs, the oesophageal hypervigilance and anxiety scale (\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Questions for the\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      were drawn from 4 existing validated measures that assessed hypervigilance and anxiety adapted for the oesophagus. Patients who previously underwent high\u2010resolution manometry testing at a university\u2010based oesophageal motility clinic were retrospectively identified. Patients were included in the analysis if they completed the\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      as well as questionnaires assessing symptom severity and health\u2010related quality of life at the time of the high\u2010resolution manometry.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine hundred and eighty\u2010two patients aged 18\u201085 completed the study. The\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      demonstrates excellent internal consistency (\u03b1\u00a0=\u00a00.93) and split\u2010half reliability (Guttman\u00a0=\u00a00.87). Inter\u2010item correlations indicated multicollinearity was not achieved; thus, no items were removed from the original 15\u2010item scale. Principal components factor analysis revealed two subscales measuring symptom\u2010specific anxiety and symptom\u2010specific hypervigilance. Construct validity for total and subscale scores was supported by positive correlations with symptom severity and negative correlations with health\u2010related quality of life.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      is a 15\u2010item scale assessing oesophageal hypervigilance and symptom\u2010specfic anxiety. The\n                      <jats:styled-content style=\"fixed-case\">EHAS<\/jats:styled-content>\n                      could be useful in evaluating the role of these constructs in several oesophageal conditions in which hypersensitivity, hypervigilance and anxiety may contribute to symptoms and impact treatment outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.14605","type":"journal-article","created":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T06:22:38Z","timestamp":1520835758000},"page":"1270-1277","source":"Crossref","is-referenced-by-count":98,"title":["Validation of the oesophageal hypervigilance and anxiety scale for chronic oesophageal disease"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4670-2441","authenticated-orcid":false,"given":"T. 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