{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:49:50Z","timestamp":1790232590419,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004099","name":"Ligue Contre le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004099","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Gastric mucosa\u2010associated lymphoid tissue (MALT) lymphoma is a rare disease, and most available data on gastric MALT lymphoma (GML) come from clinical studies of selected patients treated in centres of excellence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To analyse the clinical features, management and survival of GML patients in a population\u2010based study in France<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All new cases of GML diagnosed between 2002 and 2010 in 11 French areas covered by cancer registries were included. Pathology reports were verified and, if necessary, reviewed by an expert pathologist. All clinical data were retrospectively collected from medical files and analysed using <jats:sc>stata<\/jats:sc> V. 14 software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred and sixteen patients with confirmed GML (50% male, median age 67\u00a0years) were identified. Among them, 44 showed an early transformation into diffuse large B cell lymphoma and were considered to have had an initially missed high\u2010grade lymphoma. At diagnosis, 76% of patients were at stage IE\/II, and 24% at stage III\/IV of the disease. <jats:italic>Helicobacter pylori<\/jats:italic> infection was found in 57% of the patients. Eradication treatment was administered to 76% of patients and complete remission (CR) was obtained in 39%. One hundred and ninety patients received at least one other treatment, including 10 already in CR after eradication. Altogether, CR was obtained in 70% of patients and the 5\u2010year overall survival was 79% (95% CI [75\u201083]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In comparison to clinical series, in the general population, GMLs are more frequently diagnosed at an advanced stage, their clinical management is heterogeneous, and there is a risk of misdiagnosis and overtreatment. These results highlight the necessity of following currently available guidelines in this field.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.15409","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T09:42:55Z","timestamp":1564134175000},"page":"654-663","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Gastric MALT lymphoma in a population\u2010based study in France: clinical features, treatments and survival"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0780-6261","authenticated-orcid":false,"given":"Tamara","family":"Matysiak\u2010Budnik","sequence":"first","affiliation":[{"name":"Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Jamet","sequence":"additional","affiliation":[{"name":"Nantes 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