{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:57:08Z","timestamp":1790517428793,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,7,11]],"date-time":"2021-07-11T00:00:00Z","timestamp":1625961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psychological distress, strongly associated with functional gastrointestinal disorders (FGIDS), likely plays a central role in the pathophysiology. The role of sleep disturbances in FGIDs is unclear, and an association with psychological factors is uncertain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine whether sleep disturbances are associated with irritable bowel syndrome (IBS) and functional dyspepsia (FD) and if a potential association is explained by psychological distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult sample randomly selected from a region in New South Wales, Australia in 2015 who returned a follow\u2010up mail survey in 2018 (response rate, 60.5%) that contained questions on IBS, FD, sleep (MOS\u2010Sleep Scale) and psychological distress (Kessler 6 scale).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among this population, 10.4% (95% CI 8.8\u201012.2) and 17.9% (95% CI 15.9\u201020.1) met Rome III criteria for IBS and FD, respectively. The prevalence of any sleep disturbance at least most of the time was common, with a significantly higher prevalence in FGID (IBS and\/or FD) compared with the remaining population (41.8% vs 32.2%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.003). The total sleep problem index was significantly higher for IBS (OR\u00a0=\u00a01.71 [95% CI 1.29\u20102.27], <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001) (IBS\u2010diarrhoea predominant and IBS\u2010mixed but not IBS\u2010constipation) and FD (OR\u00a0=\u00a01.80 [1.43\u20102.26], <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001) (both epigastric pain syndrome and postprandial distress syndrome) even after adjusting for age, sex and psychological distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both IBS and FD, and most of their major subtypes except IBS\u2010C, are associated with a range of sleep disturbances. These sleep problems do not appear to be explained by psychological factors and may play an independent role in the pathophysiology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.16500","type":"journal-article","created":{"date-parts":[[2021,7,11]],"date-time":"2021-07-11T18:13:45Z","timestamp":1626027225000},"page":"627-636","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Sleep disturbances in the irritable bowel syndrome and functional dyspepsia are independent of psychological distress: a population\u2010based study of 1322 Australians"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8647-5933","authenticated-orcid":false,"given":"Natasha A.","family":"Koloski","sequence":"first","affiliation":[{"name":"College of Health, Medicine and Wellbeing University of Newcastle Callaghan New South Wales Australia"},{"name":"Department of Gastroenterology and Hepatology Princess Alexandra 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