{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T02:53:34Z","timestamp":1793933614389,"version":"4.8.0"},"reference-count":155,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The prevalence of non\u2010alcoholic fatty liver disease (NAFLD) is increasing in parallel with obesity and type 2 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To review the global epidemiology of NAFLD<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrieved articles from PubMed using search terms of NAFLD, epidemiology, prevalence, incidence, and comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Over 250 articles were reviewed. In 2016, the global NAFLD prevalence was 25%; this increased to &gt;30% in 2019. Prevalence in Asia, Latin America and Middle East\u2010North Africa (MENA) was 30.8%, 34.5% and 42.6%, respectively. Prevalence increased with age. Although prevalence was higher in men, prevalence in post\u2010menopausal women was similar. NAFLD prevalence was higher in certain subpopulations, especially among the obese and those with metabolic syndrome (MS). However, the prevalence of lean NAFLD was 11.2%. The global prevalence of non\u2010alcoholic steatohepatitis (NASH) is estimated between 2% and 6% in the general population. Approximately 7% of patients with NAFLD have advanced fibrosis; rates were between 21% and 50% among patients with NASH. Overall mortality related to NAFLD was 15\u201320 per 1000 person\u2010years, and increased substantially in patients with NASH, especially in those with components of MS. Recent data suggest mortality\/morbidity from NAFLD is increasing globally but NAFLD awareness remains low among patients and healthcare providers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>NAFLD poses a global public health problem with a very high disease burden in Asia, MENA and Latin America. Research is needed to better quantify the full impact of NAFLD and to develop strategies to improve awareness and risk stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.17158","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T08:14:54Z","timestamp":1658823294000},"page":"942-956","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":213,"title":["Review article: the epidemiologic burden of non\u2010alcoholic fatty liver disease across the world"],"prefix":"10.1111","volume":"56","author":[{"given":"Linda","family":"Henry","sequence":"first","affiliation":[{"name":"Center for Liver Diseases Department of Medicine Inova Fairfax Medical Campus  Falls Church Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Paik","sequence":"additional","affiliation":[{"name":"Betty and Guy Beatty Center for Integrated Research Inova Health System  Falls Church Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9313-577X","authenticated-orcid":false,"given":"Zobair M.","family":"Younossi","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research in Liver Diseases  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"e_1_2_21_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28431"},{"key":"e_1_2_21_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2015.10.001"},{"key":"e_1_2_21_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010012\u20102446\u20103"},{"key":"e_1_2_21_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2012.08.005"},{"key":"e_1_2_21_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.10.033"},{"key":"e_1_2_21_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2016.01.012"},{"key":"e_1_2_21_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30664"},{"key":"e_1_2_21_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31173"},{"key":"e_1_2_21_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102019\u2010318813"},{"key":"e_1_2_21_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.04.027"},{"key":"e_1_2_21_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.06.011"},{"key":"e_1_2_21_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.11.034"},{"key":"e_1_2_21_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.04.014"},{"key":"e_1_2_21_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.06.021"},{"key":"e_1_2_21_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29367"},{"key":"e_1_2_21_17_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001054"},{"key":"e_1_2_21_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102020\u2010322572"},{"key":"e_1_2_21_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102020\u2010323082"},{"key":"e_1_2_21_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102021\u2010324191"},{"key":"e_1_2_21_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2007.03426.x"},{"key":"e_1_2_21_22_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000375"},{"key":"e_1_2_21_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.01.001"},{"key":"e_1_2_21_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1710"},{"key":"e_1_2_21_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.07.020"},{"key":"e_1_2_21_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psym.2010.12.019"},{"key":"e_1_2_21_27_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i28.3669"},{"key":"e_1_2_21_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.139303"},{"key":"e_1_2_21_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.06.064"},{"key":"e_1_2_21_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28785"},{"key":"e_1_2_21_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30254"},{"key":"e_1_2_21_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13535"},{"key":"e_1_2_21_33_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc19\u20101113"},{"key":"e_1_2_21_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876\u2010021\u201001720\u2010w"},{"key":"e_1_2_21_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14825"},{"key":"e_1_2_21_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1765"},{"key":"e_1_2_21_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.06.048"},{"key":"e_1_2_21_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575\u2010021\u201000523\u20104"},{"key":"e_1_2_21_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.10.025"},{"key":"e_1_2_21_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13035"},{"key":"e_1_2_21_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15830"},{"key":"e_1_2_21_42_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.01.043"},{"key":"e_1_2_21_43_1","doi-asserted-by":"crossref","unstructured":"YounossiZY GolabiP PaikJM HenryA Van DongenC HenryL.The most recent and in\u2010depth meta\u2010analytic assessment of the global epidemiology of nonalcoholic fatty liver disease (NAFLD). EASL 2022 Late Breaker.","DOI":"10.1016\/S0168-8278(22)00668-7"},{"key":"e_1_2_21_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30039-1"},{"key":"e_1_2_21_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.05.022"},{"key":"e_1_2_21_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30702"},{"key":"e_1_2_21_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072\u2010021\u201010143\u20104"},{"key":"e_1_2_21_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000514953"},{"key":"e_1_2_21_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01240-z"},{"key":"e_1_2_21_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2021.11.010"},{"key":"e_1_2_21_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.05831.x"},{"issue":"1","key":"e_1_2_21_52_1","first-page":"14","article-title":"Prevalence of nonalcoholic steatohepatitis in Iran: a population based study","volume":"2","author":"Sohrabpour A","year":"2010","journal-title":"Middle East J Dig Dis"},{"key":"e_1_2_21_53_1","doi-asserted-by":"publisher","DOI":"10.4103\/sjg.SJG_122_18"},{"key":"e_1_2_21_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478\u20103231.2006.01311.x"},{"key":"e_1_2_21_55_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2019.19072"},{"key":"e_1_2_21_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajg.2014.01.008"},{"key":"e_1_2_21_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajg.2015.06.001"},{"key":"e_1_2_21_58_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i31.3944"},{"key":"e_1_2_21_59_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32832fcdf0"},{"key":"e_1_2_21_60_1","volume-title":"The economic cost and health burden of liver diseases in Australia","author":"Association TGSoAAL","year":"2012"},{"key":"e_1_2_21_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/osp4.13"},{"key":"e_1_2_21_62_1","unstructured":"Type 2 Diabetes Mellitus\u2014International Diabetes Federation.IDF diabetes atlas. 8th ed.2017obtained from the world wide web athttp:\/\/www.diabetesatlas.org\/"},{"key":"e_1_2_21_63_1","unstructured":"WHO Diabetes Fact Sheets and obesity and overweight. Obtained from the world wide web at:http:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/diabetes;http:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/obesity\u2010and\u2010overweight. Accessed June 15 2022."},{"key":"e_1_2_21_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2022.100706"},{"issue":"1","key":"e_1_2_21_65_1","first-page":"64","article-title":"Non\u2010alcoholic fatty liver disease in Cuba","volume":"23","author":"Barreto\u2010Su\u00e1rez E","year":"2021","journal-title":"MEDICC Rev"},{"key":"e_1_2_21_66_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612826666200303114934"},{"key":"e_1_2_21_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.05.036"},{"key":"e_1_2_21_68_1","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2019.20152"},{"key":"e_1_2_21_69_1","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20190212"},{"key":"e_1_2_21_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15009"},{"key":"e_1_2_21_71_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i47.8263"},{"key":"e_1_2_21_72_1","doi-asserted-by":"publisher","DOI":"10.1159\/000235677"},{"key":"e_1_2_21_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kws448"},{"key":"e_1_2_21_74_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-019-0972-6"},{"key":"e_1_2_21_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12036"},{"key":"e_1_2_21_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijge.2013.03.008"},{"key":"e_1_2_21_77_1","doi-asserted-by":"publisher","DOI":"10.1177\/2333794X19891305"},{"key":"e_1_2_21_78_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1212"},{"key":"e_1_2_21_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.11.021"},{"key":"e_1_2_21_80_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140908"},{"key":"e_1_2_21_81_1","doi-asserted-by":"crossref","unstructured":"LiJ LeM BarakatM CheungR NguyenM.The changing epidemiology of liver disease among United States children and adolescents from 1999\u20102016.https:\/\/ssrn.com\/abstract=3716878orhttps:\/\/doi.org\/10.2139\/ssrn.3716878","DOI":"10.2139\/ssrn.3716878"},{"key":"e_1_2_21_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1760"},{"key":"e_1_2_21_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2017.01.008"},{"key":"e_1_2_21_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12024"},{"key":"e_1_2_21_85_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-006998"},{"key":"e_1_2_21_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24773"},{"key":"e_1_2_21_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.04.047"},{"key":"e_1_2_21_88_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.09.038"},{"key":"e_1_2_21_89_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26761"},{"key":"e_1_2_21_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.08.043"},{"key":"e_1_2_21_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4492-3"},{"key":"e_1_2_21_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.04.067"},{"key":"e_1_2_21_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30251"},{"key":"e_1_2_21_94_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.795421"},{"key":"e_1_2_21_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.09.041"},{"key":"e_1_2_21_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14038"},{"key":"e_1_2_21_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28677"},{"key":"e_1_2_21_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072\u2010020\u201010023\u20103"},{"key":"e_1_2_21_99_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa575"},{"issue":"2020","key":"e_1_2_21_100_1","first-page":"5023157","article-title":"The prevalence of NAFLD and fibrosis in bariatric surgery patients and the reliability of noninvasive diagnostic methods","volume":"26","author":"Soresi M","year":"2020","journal-title":"Biomed Res Int"},{"key":"e_1_2_21_101_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18041892"},{"key":"e_1_2_21_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-018-0588-8"},{"key":"e_1_2_21_103_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwk028"},{"key":"e_1_2_21_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthplace.2016.12.001"},{"key":"e_1_2_21_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2011.11.036"},{"key":"e_1_2_21_106_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1103216"},{"key":"e_1_2_21_107_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwx302"},{"key":"e_1_2_21_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(18)30111-7"},{"key":"e_1_2_21_109_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002527"},{"key":"e_1_2_21_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32207"},{"key":"e_1_2_21_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2012.08.011"},{"key":"e_1_2_21_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1519"},{"key":"e_1_2_21_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14112"},{"key":"e_1_2_21_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20101253(20)30077\u20107"},{"key":"e_1_2_21_115_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i47.17932"},{"key":"e_1_2_21_116_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15156"},{"key":"e_1_2_21_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1124"},{"key":"e_1_2_21_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(14)63307-2"},{"key":"e_1_2_21_119_1","unstructured":"NabiO LapidusN LacombeK BoursierJ MathurinP L\u00e9dinghenVD et al.Lean NAFLD from the general French population have more severe liver disease and poorer clinical outcomes (NASH\u2010CO Study). EASL International Liver Congress June 23\u201326 2021. Abstract OS\u2010612. 2."},{"key":"e_1_2_21_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28697"},{"key":"e_1_2_21_121_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29085"},{"key":"e_1_2_21_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.03.033"},{"key":"e_1_2_21_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.07.027"},{"key":"e_1_2_21_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.12.015"},{"key":"e_1_2_21_125_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102020\u2010322786"},{"key":"e_1_2_21_126_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-018-09926-z"},{"key":"e_1_2_21_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13397"},{"issue":"1","key":"e_1_2_21_128_1","first-page":"1023","article-title":"A multi\u2010center study exploring the association of metabolic syndrome and non\u2010alcoholic fatty liver disease in Cuban patients","volume":"5","author":"Castellanos\u2010Fern\u00e1ndez MI","year":"2021","journal-title":"Austin J Obes Metab Synd"},{"key":"e_1_2_21_129_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.01.003"},{"key":"e_1_2_21_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30349-8"},{"key":"e_1_2_21_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32228"},{"key":"e_1_2_21_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2021.101754"},{"key":"e_1_2_21_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1707"},{"key":"e_1_2_21_134_1","unstructured":"World Health Organization (WHO).World Cancer Mortality. Accessed on 4 July 2022. Obtained from the world wide web at:https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/cancer"},{"key":"e_1_2_21_135_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_21_136_1","unstructured":"PaikJM HenryL YounossiY OngJ AlQahtaniA YounossiZM.The Global Burden of Liver Cancer (LC) and Chronic Liver Diseases (CLD) from 2009 to 2019. Late Breaker Abstract EASL 2022."},{"key":"e_1_2_21_137_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1510"},{"key":"e_1_2_21_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13583"},{"key":"e_1_2_21_139_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29498"},{"key":"e_1_2_21_140_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2007.02025.x"},{"key":"e_1_2_21_141_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr453"},{"key":"e_1_2_21_142_1","first-page":"30137","article-title":"Association between fibrosis stage and outcomes of patients with non\u2010alcoholic fatty liver disease: a systematic review and meta\u2010analysis","volume":"20","author":"Taylor R","year":"2020","journal-title":"Gastroenterology"},{"key":"e_1_2_21_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-016-0001-8"},{"key":"e_1_2_21_144_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001075"},{"key":"e_1_2_21_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(18)30154-2"},{"key":"e_1_2_21_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1419"},{"key":"e_1_2_21_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00308-3"},{"key":"e_1_2_21_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1534"},{"key":"e_1_2_21_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552\u2010018\u20101095\u2010z"},{"key":"e_1_2_21_150_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944\u2010020\u201001288\u20106"},{"key":"e_1_2_21_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31845"},{"key":"e_1_2_21_152_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902\u2010020\u201000582\u20109"},{"key":"e_1_2_21_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.05.064"},{"key":"e_1_2_21_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.05.057"},{"key":"e_1_2_21_155_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1915"},{"key":"e_1_2_21_156_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011518"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apt.17158","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/apt.17158","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/apt.17158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T18:51:46Z","timestamp":1692730306000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.17158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,26]]},"references-count":155,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/apt.17158"],"URL":"https:\/\/doi.org\/10.1111\/apt.17158","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,26]]},"assertion":[{"value":"2022-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}