{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:02:59Z","timestamp":1790877779841,"version":"4.1.0"},"reference-count":63,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012276","name":"Tillotts Pharma","doi-asserted-by":"publisher","award":["RG.GASS.124592"],"award-info":[{"award-number":["RG.GASS.124592"]}],"id":[{"id":"10.13039\/501100012276","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Little is known about faecal incontinence (FI) in individuals with irritable bowel syndrome (IBS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare characteristics of people with IBS reporting FI, compared with people with IBS who do not report FI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected demographic, gastrointestinal and psychological symptoms, healthcare usage, direct healthcare costs, impact on work and activities of daily living, and quality of life data from individuals with Rome IV\u2010defined IBS. We asked participants about FI, assigning presence or absence according to Rome\u2010IV criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 752 participants with Rome IV IBS, 202 (26.9%) met Rome IV criteria for FI. Individuals with FI were older (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001), more likely to have IBS\u2010D (47.0% vs. 39.0%, <jats:italic>p<\/jats:italic>\u00a0=\u20090.008), and less likely to have attained a university or postgraduate level of education (31.2% vs. 45.6%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001), or to have an annual income of \u2265\u00a330,000 (18.2% vs. 32.9%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001). They were more likely to report urgency (44.6% vs. 19.1%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001) as their most troublesome symptom and a greater proportion had severe IBS symptom scores, abnormal depression scores, higher somatic symptom\u2010reporting scores or higher gastrointestinal symptom\u2010specific anxiety scores (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.01 for trend for all analyses). Mean health\u2010related quality of life scores were significantly lower among those with, compared with those without, FI (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001). Finally, FI was associated with higher IBS\u2010related direct healthcare costs (<jats:italic>p<\/jats:italic>\u00a0=\u20090.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among individuals with Rome IV IBS, one\u2010in\u2010four repo rted FI according to Rome IV criteria. Physicians should ask patients with IBS about FI routinely.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.17465","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T04:59:06Z","timestamp":1678769946000},"page":"1083-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Prevalence and impact of faecal incontinence among individuals with Rome IV irritable bowel syndrome"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9483-5604","authenticated-orcid":false,"given":"Vivek C.","family":"Goodoory","sequence":"first","affiliation":[{"name":"Leeds Institute of Medical Research at St. James's, University of Leeds  Leeds UK"},{"name":"Leeds Gastroenterology Institute, St. James's University Hospital  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cho E.","family":"Ng","sequence":"additional","affiliation":[{"name":"County Durham 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