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The aim of this meta\u2010analysis was to estimate the rate of post\u2010COVID\u201019 FD and IBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      MEDLINE, Scopus and Embase were searched through 17 December 2022. Studies reporting the incidence of FD and\/or IBS in COVID\u201019 survivors and controls (without COVID\u201019), when available, according to the Rome criteria, were included. Estimated incidence with 95% confidence intervals (CI) was pooled. The odds ratio (OR) with 95% confidence intervals (CI) was pooled; heterogeneity was expressed as\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten studies met the inclusion criteria and were included in the analysis. Overall, four studies including 1199 COVID\u201019 patients were considered for FD. Post\u2010COVID\u201019 FD was reported by 72 patients (4%, 95% CI: 3%\u20135% and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      0%). The pooled OR for FD development (three studies) in post\u2010COVID\u201019 patients compared to controls was 8.07 (95% CI: 0.84\u201377.87,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.071 and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200967.9%). Overall, 10 studies including 2763 COVID\u201019 patients were considered for IBS. Post\u2010COVID\u201019 IBS was reported by 195 patients (12%, 95% CI: 8%\u201316%,\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      95.6% and Egger's\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002 test). The pooled OR for IBS development (four studies) in COVID\u201019 patients compared to controls was 6.27 (95% CI: 0.88\u201344.76,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.067 and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200981.4%); considering only studies with a prospective COVID\u201019 cohort (three studies), the pooled OR was 12.92 (95% CI: 3.58\u201346.60,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>COVID\u201019 survivors were found to be at risk for IBS development compared to controls. No definitive data are available for FD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.17513","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T00:53:33Z","timestamp":1681174413000},"page":"6-15","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Meta\u2010analysis: Post\u2010COVID\u201019 functional dyspepsia and irritable bowel syndrome"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7167-8773","authenticated-orcid":false,"given":"Giovanni","family":"Marasco","sequence":"first","affiliation":[{"name":"IRCCS Azienda Ospedaliero Universitaria di Bologna  Bologna Italy"},{"name":"Department of Medical and Surgical Science University of Bologna  Bologna 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