{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:24:18Z","timestamp":1792153458479,"version":"4.4.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Baveno VI and VII criteria are used in patients with cirrhosis to rule out large size oesophageal varices (EV) and rule in\/out clinically significant portal hypertension (CSPH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate their diagnostic performance in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively included all patients with Child\u2010Pugh A cirrhosis and HCC who had endoscopy, liver stiffness measurement (LSM) and platelet count within 6\u2009months. They were classified according to the BCLC stage. Favourable Baveno VI criteria were defined by LSM\u2009&lt;\u200920\u2009kPa and platelets &gt;\u2009150\u2009G\/L (to rule out large EV), favourable Baveno VII criteria if LSM\u2009\u2264\u200915\u2009kPa and platelets \u2265\u2009150\u2009G\/L (to rule out CSPH, which was defined by a HVPG\u2009\u2265\u200910\u2009mm\u2009Hg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 185 patients; 46% were\u00a0BCLC\u20100\/A, 28% BCLC\u2010B and 26% BCLC\u2010C. EV were present in 44% (23% large), and HVPG\u2009\u2265\u200910\u2009mm\u2009Hg in 42% (mean 8\u2009mm\u2009Hg). In patients with favourable Baveno VI criteria, 8% of the whole cohort (Se 93%, NPV 92%), 11% of BCLC\u20100\u2010A (Se 89%, NPV 89%) and 10.0% of BCLC\u2010C patients (Se 91%, NPV 90%) had large EV. Among patients with HVPG\u2009&lt;\u200910\u2009mm\u2009Hg, 6% had large EV and 17% small. CSPH was present in 23% of patients with favourable Baveno VII criteria among the whole cohort, and in 25% of those with BCLC\u20100\/A. The specificity of LSM\u2009\u2265\u200925\u2009kPa to rule in CSPH was 48%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Favourable Baveno VI criteria are not appropriate to rule out the presence of high\u2010risk EV, or Baveno VII criteria to rule CSPH\u00a0in\/out in patients with HCC.<\/jats:p><\/jats:sec>","DOI":"10.1111\/apt.17599","type":"journal-article","created":{"date-parts":[[2023,6,10]],"date-time":"2023-06-10T05:34:16Z","timestamp":1686375256000},"page":"346-356","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Baveno VI and VII criteria are not suitable for screening for large varices or clinically significant portal hypertension in patients with hepatocellular carcinoma"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-8016","authenticated-orcid":false,"given":"Manon","family":"Allaire","sequence":"first","affiliation":[{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"},{"name":"Centre de Recherche des Cordeliers INSERM UMR 1138  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertille","family":"Campion","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alix","family":"Demory","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9patologie, AP\u2010HP Sorbonne Paris Nord H\u00f4pitaux Universitaire Paris Seine Saint\u2010Denis  Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Larrey","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Wagner","sequence":"additional","affiliation":[{"name":"Service de Radiologie Diagnostique AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marika","family":"Rudler","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Roux","sequence":"additional","affiliation":[{"name":"Service de Radiologie Interventionnelle AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Blaise","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9patologie, AP\u2010HP Sorbonne Paris Nord H\u00f4pitaux Universitaire Paris Seine Saint\u2010Denis  Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie G.","family":"Carrie","sequence":"additional","affiliation":[{"name":"Centre de Recherche des Cordeliers INSERM UMR 1138  Paris France"},{"name":"Service d'H\u00e9patologie, AP\u2010HP Sorbonne Paris Nord H\u00f4pitaux Universitaire Paris Seine Saint\u2010Denis  Bobigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Thabut","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie AP\u2010HP Sorbonne Universit\u00e9, H\u00f4pital Universitaire Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"},{"name":"Centre de Recherche Saint\u2010Antoine (CRSA) Institute of Cardiometabolism and Nutrition (ICAN), Sorbonne Universit\u00e9, INSERM  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.12.022"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.05.022"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27431"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.07.014"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12188"},{"issue":"1","key":"e_1_2_8_7_1","first-page":"256","article-title":"Definitions, methodology and therapeutic strategies in portal hypertension. 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