{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:49:32Z","timestamp":1784742572328,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Irritable bowel syndrome is a disorder of the gut\u2010brain interaction characterised by chronic abdominal pain and altered bowel habits, with substantial impact on quality of life. Symptoms are associated with foods trigger, leading to specific dietary interventions. Adherence and acceptability may improve when dietary interventions are personalised and less restrictive. While the low\u2010FODMAP diet is effective, its restrictiveness may limit long\u2010term adherence. Personalised dietary strategies may offer comparable benefit with greater feasibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this parallel\u2010group, randomised clinical trial, adults fulfilling Rome III criteria for IBS were assigned (1:1) to NICE dietary advice or an personalised FODMAP diet for four weeks. The personalised diet involved selective 50% reduction of patient\u2010specific high\u2010FODMAP foods identified through structured food and symptom diaries. Symptoms were evaluated using a 4\u2010point Likert scale, with adequate relief defined as \u2265\u20091\u2010point improvement in both abdominal pain and bowel habits. Dietary intake, quality of life (SF\u201036) and anthropometric measures were recorded at baseline and follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010nine participants were enrolled (85% women; mean age 39.9\u2009\u00b1\u200912.2\u2009years). Baseline demographics, anthropometric variables and IBS subtypes were similar across groups. Both interventions significantly reduced caloric intake and improved symptom severity, particularly abdominal pain, distension, constipation and diarrhoea. Adequate relief occurred in 41.2% of the NICE group and 54.5% of the personalised FODMAP group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.33). No significant between\u2010group differences were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An individualised, less restrictive personalised FODMAP diet yields symptom improvement comparable to NICE dietary advice while preserving nutritional adequacy. Personalised dietary strategies may enhance feasibility and long\u2010term adherence in IBS management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.70601","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:08:29Z","timestamp":1772996909000},"page":"1529-1536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of a Personalised\n                    <scp>FODMAP<\/scp>\n                    Diet Versus the National Institute for Health and Care Excellence (\n                    <scp>NICE<\/scp>\n                    ) Dietary Advice on Symptom Control in Patients With Irritable Bowel Syndrome: Randomised Clinical Trial"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3114-1493","authenticated-orcid":false,"given":"Mar\u00eda Fernanda","family":"Garcia\u2010Cedillo","sequence":"first","affiliation":[{"name":"Gastrointestinal Motility Laboratory, Department of Gastroenterology Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2039-3831","authenticated-orcid":false,"given":"Mar\u00eda Fernanda","family":"Huerta\u2010de la Torre","sequence":"additional","affiliation":[{"name":"Gastrointestinal Motility Laboratory, Department of Gastroenterology Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3819-7198","authenticated-orcid":false,"given":"Josealberto Sebastiano","family":"Arenas\u2010Martinez","sequence":"additional","affiliation":[{"name":"Gastrointestinal Motility Laboratory, Department of Gastroenterology Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8569-2792","authenticated-orcid":false,"given":"Enrique","family":"Coss\u2010Adame","sequence":"additional","affiliation":[{"name":"Gastrointestinal Motility Laboratory, Department of Gastroenterology Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.22532"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-325214"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(24)00238-3"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001767"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(25)00054-8"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182942"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3FO03717G"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.12.248"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41395-018-0084-x"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15410"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2019.02.012"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i18.5677"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.06.099"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.02.045"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-313750"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmx.2018.05.005"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.07.054"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001036"}],"updated-by":[{"DOI":"10.1111\/apt.70788","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000}}],"container-title":["Alimentary Pharmacology &amp; 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