{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:07:06Z","timestamp":1779883626849,"version":"3.53.1"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Post\u2010operative recurrence (POR) of colonic Crohn's Disease (CD) after segmental (SC) or subtotal colectomy (STC) is scarcely described. Therefore, we aimed to report the rates and predictors of POR in this setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Multicentre, nationwide, retrospective study including colonic CD patients undergoing SC or STC. Clinical, endoscopic, radiologic and surgical POR were assessed and POR\u2010free survival was compared between procedures. Cox regression determined predictors of post\u2010colectomy POR. Inverse probability of treatment weighting (IPTW) was carried out for sensitivity analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 224 patients were included (157 SC, 67 STC). Clinical POR occurred less frequently after SC than after STC (38% vs 63%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), as did endoscopic POR (50% vs 71%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012); whereas radiologic and surgical POR rates were similar (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.1 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.992, respectively). Clinical POR\u2010free survival at 1 and 5\u2009years was higher after SC than after STC (82% and 64.8% vs 67.6% and 39%, log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Endoscopic POR\u2010free survival followed a similar pattern (log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In multivariable Cox regression, SC remained protective against clinical (HR 0.54 [0.36\u20130.81]) and early endoscopic POR (HR 0.54 [0.35\u20130.82]). After IPTW, SC was still associated with a significantly lower risk of clinical and endoscopic POR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Clinical and endoscopic POR rates are significantly lower following SC compared with STC in colonic CD, while radiologic and surgical recurrence rates were similar. SC shows a protective effect regarding clinical and early endoscopic POR. These data support segmental resection of colonic CD when feasible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.70608","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:46:26Z","timestamp":1773305186000},"page":"1605-1616","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Post\u2010Operative Recurrence of Colonic Crohn's Disease After Colectomy: The RESECOL Study by the Young Group of GETECCU"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4487-452X","authenticated-orcid":false,"given":"J. L.","family":"Rueda Garc\u00eda","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario La Paz  Madrid Spain"},{"name":"La Paz Institute for Health Research (IdiPAZ), IdiPAZ Study Group on Immune\u2010Mediated Gastrointestinal Diseases  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1789-3784","authenticated-orcid":false,"given":"C.","family":"Su\u00e1rez Ferrer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario La Paz  Madrid Spain"},{"name":"La Paz Institute for Health Research (IdiPAZ), IdiPAZ Study Group on Immune\u2010Mediated Gastrointestinal Diseases  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Garc\u00eda de la Filia Molina","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Ram\u00f3n y Cajal  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Rivas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario Marqu\u00e9s de Valdecilla  Santander Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Fern\u00e1ndez\u2010Clotet","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Cl\u00ednic  Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD) Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"C\u00e9spedes Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Mart\u00ednez Cuevas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital R\u00edo Hortega  Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-2577","authenticated-orcid":false,"given":"D. C.","family":"Balderramo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Privado Universitario de C\u00f3rdoba  C\u00f3rdoba Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Arias","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario de Burgos  Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6274-1686","authenticated-orcid":false,"given":"H.","family":"Mart\u00ednez Lozano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario Gregorio Mara\u00f1\u00f3n  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3913-3412","authenticated-orcid":false,"given":"M.","family":"Vaamonde Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario Donostia  Donostia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2335-3792","authenticated-orcid":false,"given":"M.","family":"Calafat","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD) Instituto de Salud Carlos III  Madrid Spain"},{"name":"Department of Gastroenterology Hospital Universitari Germans Trias i Pujol  Badalona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Mart\u00edn Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hospital Universitario Infanta Cristina  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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