{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:49:39Z","timestamp":1791906579687,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010823","name":"Tore Nilsons Stiftelse f\u00f6r Medicinsk Forskning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007435","name":"\u00c5ke Wiberg Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007435","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006285","name":"Magnus Bergvalls Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006285","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004722","name":"Stiftelsen Lars Hiertas Minne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004722","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Surveillance for hepatocellular carcinoma (HCC) aims to enable early diagnosis and receipt of curative\u2010intent treatment; however, socioeconomic status (SES) influences both participation in surveillance and subsequent outcomes. Whether SES\u2010related disparities persist among individuals diagnosed through surveillance remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To examine sociodemographic factors associated with receipt of curative\u2010intent treatment and mortality among individuals with surveillance\u2010detected HCC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a nationwide cohort study including adults with cirrhosis and surveillance\u2010detected HCC diagnosed in Sweden between January 1, 2012, and December 31, 2022. Sociodemographic data and outcomes were obtained through linkage to national registers. The primary outcome was receipt of curative\u2010intent treatment, analysed using multivariable logistic regression. Post\u2010treatment mortality was assessed using multivariable Cox regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 1,514 individuals with surveillance\u2010detected HCC, 845 (56%) were diagnosed at an early stage, and 974 (64%) received curative\u2010intent treatment. After adjustment for tumour characteristics, liver disease aetiology and severity, performance status, comorbidities, and calendar period, low SES was independently associated with a lower likelihood of receiving curative\u2010intent treatment (adjusted odds ratio 0.42, 95% CI 0.26\u20130.66, low vs. high SES). Among those treated with curative intent, low SES was also associated with higher mortality (adjusted hazard ratio 1.50, 95% CI 1.10\u20132.00).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Socioeconomic inequalities in the receipt of curative\u2010intent treatment and survival persist even among individuals with surveillance\u2010detected HCC within a universal healthcare system. These findings indicate that surveillance alone is insufficient to ensure equitable outcomes and underscore the need for regionally tailored, people\u2010centred strategies that address social vulnerability across the HCC care continuum.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/apt.70753","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:29:32Z","timestamp":1779859772000},"page":"647-658","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Socioeconomic Inequalities in Receipt of Curative\u2010Intent Treatment and Survival After Surveillance\u2010Detected Hepatocellular Carcinoma: A Nationwide Cohort Study"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8474-1759","authenticated-orcid":false,"given":"Hannes","family":"Hagstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Medicine, Huddinge Karolinska Institutet  Stockholm Sweden"},{"name":"Unit of Hepatology, Department of Upper GI Diseases Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9618-2299","authenticated-orcid":false,"given":"Jeffrey V.","family":"Lazarus","sequence":"additional","affiliation":[{"name":"City University of New York Graduate School of Public Health &amp; Health Policy (CUNY SPH)  New York USA"},{"name":"Barcelona Institute for Global Health (ISGlobal)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5274-7726","authenticated-orcid":false,"given":"Malin Sternby","family":"Eilard","sequence":"additional","affiliation":[{"name":"Department of Transplantation Sahlgrenska University Hospital  Gothenburg Region V\u00e4stra G\u00f6taland Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Bergman","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9791-5247","authenticated-orcid":false,"given":"Magnus","family":"Rizell","sequence":"additional","affiliation":[{"name":"Department of Transplantation Sahlgrenska University Hospital  Gothenburg Region V\u00e4stra G\u00f6taland Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8078-9528","authenticated-orcid":false,"given":"Per","family":"Sandstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"},{"name":"Clinical Department of Surgery in Link\u00f6ping Region \u00d6sterg\u00f6tland  Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7232-8000","authenticated-orcid":false,"given":"Juan","family":"Vaz","sequence":"additional","affiliation":[{"name":"Department of Medicine, Huddinge Karolinska Institutet  Stockholm Sweden"},{"name":"School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01200-4"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.08.028"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000466"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.07.032"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.01.023"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31309"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.11.018"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.12.031"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.101969"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2025.101273"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2021.09.018"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.50226"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2021.1878550"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(25)00228-2"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33993"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/14034948211030353"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-025-01221-0"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2020.1820566"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13570"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S420130"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2025.2517208"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01701-3"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2022.100578"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2025.2487539"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03759-8"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2023.03.043"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2025.101480"}],"container-title":["Alimentary Pharmacology &amp; 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