{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T20:06:53Z","timestamp":1748376413796},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The laparoscopic approach is accepted as a treatment option for patients with ulcerative colitis (<jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>) who are otherwise in good health. However, its application for patients with severe <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> remains controversial. The purpose of this study was to evaluate the feasibility of the laparoscopic approach for severe <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> cases. Short\u2010 and long\u2010term clinical outcomes after laparoscopic total proctocolectomy with ileal pouch\u2010anal anastomosis were compared between severe and mild\u2010to\u2010intermediate <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cases treated between <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2002 and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2010 were retrieved retrospectively from the database of <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>yoto <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edical <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>enter and <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>yoto <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital. Intraoperative complications and short\u2010 and long\u2010term clinical outcomes were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 31 patients underwent laparoscopic total proctocolectomy with ileal pouch\u2010anal anastomosis. A comparison of short\u2010 and long\u2010term clinical outcomes after one\u2010 or two\u2010stage laparoscopic ileal pouch\u2010anal anastomosis between severe (<jats:italic>n<\/jats:italic>\u2009=\u20097) and mild\u2010to\u2010intermediate (<jats:italic>n<\/jats:italic>\u2009=\u200921) <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patients revealed no significant differences. The proportion of patients with restoration of intestinal continuity did not differ between the groups (severe: 86%, mild to intermediate: 95%; <jats:italic>P<\/jats:italic>\u2009=\u20090.69).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present findings suggest that laparoscopic total proctocolectomy with ileal pouch\u2010anal anastomosis for severe <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patients could be a good alternative approach when performed by an experienced hand.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ases.12046","type":"journal-article","created":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T05:12:55Z","timestamp":1372655575000},"page":"271-278","source":"Crossref","is-referenced-by-count":8,"title":["Feasibility and safety of laparoscopic total proctocolectomy with ileal pouch\u2010anal anastomosis for severe ulcerative colitis"],"prefix":"10.1111","volume":"6","author":[{"given":"Junichiro","family":"Kawamura","sequence":"first","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"},{"name":"Department of Surgery Shiga Medical Center for Adults  Moriyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suguru","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kawada","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nagayama","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"},{"name":"Department of Gastroenterological Surgery Cancer Institute Hospital Japanese Foundation for Cancer Research  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Matsusue","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"},{"name":"Department of Surgery Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinari","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"},{"name":"Department of Surgery Kitano Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiharu","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Surgery Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Japan Intractable Diseases Information Center.Data from the Japan Intractable Diseases Information Center. 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