{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T06:44:28Z","timestamp":1747982668128},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T00:00:00Z","timestamp":1504051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Solitary mediastinal lymph node metastasis of hepatocellular carcinoma (HCC) is rare. We report a case of metachronically solitary mediastinal metastases of HCC treated by video\u2010assisted thoracic surgery (VATS) twice. A 66\u2010year\u2010old man underwent repeated laparoscopic radiofrequency ablation or trans\u2010arterial catheter chemo\u2010embolization against HCC for more than 10\u00a0years. The level of alpha fetoprotein protein was elevated, and radiological modalities including FDG\u2010PET revealed solitary mediastinal tumor metachronically. VATS was performed bilaterally twice. The postoperative course was uneventful and there had no recurrence of extra\u2010hepatic metastases and tumor markers are within normal limits at 18\u00a0months after second VATS. VATS is a minimally invasive and useful procedure for solitary mediastinal lymph node metastasis of HCC. If primary HCC was controlled and lymph node metastasis was solitary, mediastinum lymphadenectomy using VATS might give good short and long term results.<\/jats:p>","DOI":"10.1111\/ases.12414","type":"journal-article","created":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T11:10:34Z","timestamp":1504177834000},"page":"64-67","source":"Crossref","is-referenced-by-count":3,"title":["Metachronous solitary mediastinal lymph node metastases of hepatocellular carcinoma treated by video\u2010assisted thoracic surgery twice: Report of a case"],"prefix":"10.1111","volume":"11","author":[{"given":"Masatake","family":"Taniguchi","sequence":"first","affiliation":[{"name":"Department of Surgery Haga Red Cross Hospital  Tochigi Japan"},{"name":"Department of Gastrointestinal Surgery Jichi Medical University  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanobu","family":"Hyodo","sequence":"additional","affiliation":[{"name":"Department of Surgery Haga Red 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