{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T23:02:47Z","timestamp":1762210967102,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The aim of this study was to clarify the impact of dementia on surgical outcomes of laparoscopic cholecystectomy for symptomatic cholelithiasis and acute cholecystitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed medical data of 96 patients who underwent laparoscopic cholecystectomy for symptomatic cholecystitis and acute cholecystitis. The patients were divided into the dementia group (n = 18) and non\u2010dementia group (n = 78). Clinical features of the patients and surgical outcomes were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age and rates of The American Society of Anesthesiologists Physical Status classification score\u2009&gt;\u20092 in the dementia group were significantly higher than those of the non\u2010dementia group (<jats:italic>P<\/jats:italic> &lt; .001, <jats:italic>P<\/jats:italic> = .008, respectively). Incidences of acute cholecystitis and the rate of percutaneous transhepatic gallbladder drainage in the dementia group were significantly higher than those of the non\u2010dementia group (<jats:italic>P<\/jats:italic> = .009, <jats:italic>P<\/jats:italic> = .01, respectively). The rates of conversion to laparotomy and non\u2010surgical complications in the dementia group were higher than those in the non\u2010dementia group (<jats:italic>P<\/jats:italic> = .02, <jats:italic>P<\/jats:italic> = .03, respectively). Postoperative hospital stay in the dementia group was significantly longer than that in the non\u2010dementia group (15.2\u2009\u00b1\u20099.3 vs 8.2\u2009\u00b1\u20093.2 days, <jats:italic>P<\/jats:italic> = .009). Subgroup analysis of patients with acute cholecystitis showed postoperative hospital stay in the dementia group to be significantly longer than that in the non\u2010dementia group (18.7\u2009\u00b1\u200910.7 vs 10.3\u2009\u00b1\u20094.2 days, <jats:italic>P<\/jats:italic> = .03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with dementia who underwent laparoscopic cholecystectomy have a high incidence of acute cholecystitis and a high rate of percutaneous transhepatic gallbladder drainage, which may result in increased rates of conversion to laparotomy and prolong the postoperative hospital stay.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ases.12743","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T08:44:00Z","timestamp":1565167440000},"page":"351-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The impact of dementia on surgical outcomes of laparoscopic cholecystectomy for symptomatic cholelithiasis and acute cholecystitis: A retrospective study"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3608-2146","authenticated-orcid":false,"given":"Shigeo","family":"Ninomiya","sequence":"first","affiliation":[{"name":"Department of Surgery Cosmos Hospital  Usuki Japan"},{"name":"Department of Gastroenterological and Pediatric Surgery Oita University Faculty of Medicine  Yufu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Amano","sequence":"additional","affiliation":[{"name":"Department of Surgery Cosmos Hospital  Usuki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Surgery Cosmos Hospital  Usuki 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