{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:43:46Z","timestamp":1747183426456,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Familial gastrointestinal stromal tumor (GIST) is an exceedingly rare disease characterized by mutations in the <jats:italic>c\u2010kit<\/jats:italic> and platelet\u2010derived growth factor receptor alpha genes. We report the case of a 73\u2010year\u2010old woman with multiple submucosal tumors (SMTs) in the stomach and small intestine. Her elder sister had previously presented with multiple SMTs on examination and underwent surgery to remove the tumors because they showed a tendency to increase in size during follow\u2010up. The sister's tumors were pathologically diagnosed as GISTs, and a germ line mutation was recognized in exon 17 of <jats:italic>c\u2010kit<\/jats:italic>. Subsequently, the patient presented with multiple SMTs and the same germ line mutation as her sister. After 9\u2009years of follow\u2010up, a single tumor was found to have grown in size, and SILS was performed for this SMT, which was also pathologically diagnosed as a GIST. To our knowledge, this is the first report of laparoscopic surgery for a case of familial GIST.<\/jats:p>","DOI":"10.1111\/ases.12837","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T06:40:13Z","timestamp":1594363213000},"page":"250-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic surgery for familial multiple gastrointestinal stromal tumors with germ line <i>c\u2010kit<\/i> gene mutation"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9264-6057","authenticated-orcid":false,"given":"Masahiro","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2397-1478","authenticated-orcid":false,"given":"Tsuyoshi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyokazu","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukinori","family":"Kurokawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8123-687X","authenticated-orcid":false,"given":"Yasuhiro","family":"Miyazaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Makino","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetoshi","family":"Eguchi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Doki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Graduate School of Medicine, Osaka University  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/1209"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-006-9065-z"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079666"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(03)01046-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.11466"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70321-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.10.079"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.6.793"},{"key":"e_1_2_7_10_1","first-page":"S1","article-title":"NCCN GIST Task Force. NCCN Task Force report: optimal management of patients with gastrointestinal stromal tumor (GIST)\u2014expansion and update of NCCN Clinical Practice Guidelines","volume":"1","author":"Demetri GD","year":"2004","journal-title":"J Natl Compr Canc Netw."},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2005.08.011"}],"container-title":["Asian Journal of Endoscopic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fases.12837","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ases.12837","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ases.12837","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ases.12837","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T01:25:35Z","timestamp":1693617935000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ases.12837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,9]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1111\/ases.12837"],"URL":"https:\/\/doi.org\/10.1111\/ases.12837","archive":["Portico"],"relation":{},"ISSN":["1758-5902","1758-5910"],"issn-type":[{"type":"print","value":"1758-5902"},{"type":"electronic","value":"1758-5910"}],"subject":[],"published":{"date-parts":[[2020,7,9]]},"assertion":[{"value":"2020-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}