{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:48:56Z","timestamp":1792194536988,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":125,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Surgery for acute cholecystitis is time\u2010critical; the timing of laparoscopic cholecystectomy in acute cholecystitis patients has historically been controversial because of a perceived increased risk of complications. The aim is to evaluate the impact of operative timing within 7\u2009days of symptom onset on patient outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A retrospective cohort study of patients who underwent laparoscopic cholecystectomy within 7\u2009days after being admitted for acute cholecystitis between January 2016 and December 2021 in the Acute Care Surgery section. The study was conducted by dividing the study population into seven groups based on the operation day for each patient to evaluate the impact of operative timing on postoperative outcomes and compare the clinical results to determine how long the operation will be safe.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Within the study period, 3299 acute cholecystitis patients underwent laparoscopic cholecystectomy. The mean age was 42.4\u2009years, with 50.1% of them being women and 49.9% of them being men. The rate of patients older than 65\u2009years was 6.2%. A total of 237 patients (7.18%) had complications; the conversion to open surgery occurred in 27 patients (0.8%); and the overall reoperation rate was 0.5% (17 patients).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study shows that delays in laparoscopic cholecystectomy scheduling for acute cholecystitis after 3\u2009days from the onset of symptoms can lead to a longer operative duration as well as a longer hospital stay. However, it does not significantly impact overall complications and reoperation rates, allowing a feasible and safe procedure to be performed within 7\u2009days.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ases.70052","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T19:24:48Z","timestamp":1746559488000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Early Laparoscopic Cholecystectomy for Acute Cholecystitis. When Do Risks Seem Imminent?"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9878-4277","authenticated-orcid":false,"given":"Salah","family":"Mansor","sequence":"first","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"},{"name":"General Surgery Department Al\u2010Jalla Teaching Hospital, Benghazi University  Benghazi Libya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4757-9100","authenticated-orcid":false,"given":"Amine","family":"Zaidi","sequence":"additional","affiliation":[{"name":"College of Medicine Qatar University  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2728-5339","authenticated-orcid":false,"given":"Mohammad","family":"Habibullah","sequence":"additional","affiliation":[{"name":"College of Medicine Qatar University  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1732-3573","authenticated-orcid":false,"given":"Rizeq","family":"Hourani","sequence":"additional","affiliation":[{"name":"College of Medicine Qatar University  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0836-8419","authenticated-orcid":false,"given":"Yazan","family":"Aldali","sequence":"additional","affiliation":[{"name":"College of Medicine Qatar University  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3892-1273","authenticated-orcid":false,"given":"Mohamed Said","family":"Ghali","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"},{"name":"General Surgery Department Ain Shams University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salahaldeen","family":"Dawdi","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idress","family":"Suliman","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alobahi","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"},{"name":"College of Medicine Qatar University  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutfi","family":"Jarboa","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Valiyapurayil","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7399-5497","authenticated-orcid":false,"given":"Ahmad","family":"Zarour","sequence":"additional","affiliation":[{"name":"Acute Care Surgery Section Hamad General Hospital, HMC  Doha Qatar"},{"name":"College of Medicine Qatar University  Doha Qatar"},{"name":"Weill Cornell Medical College  Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200112000-00005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.5578\/turkjsurg.4208"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/POR.S169255"},{"key":"e_1_2_9_5_1","volume-title":"Acute Calculous Cholecystitis: Clinical Features and Diagnosis","author":"Zakko S. 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