{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T15:11:38Z","timestamp":1778944298150,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T00:00:00Z","timestamp":1745107200000},"content-version":"vor","delay-in-days":109,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Lymphangioleiomyomatosis (LAM) is often complicated by chylothorax and may require surgical intervention; however, the treatment is complicated because of difficulties in identifying the location of the fistula intraoperatively. This is the first report to identify the site of a chyle fistula associated with LAM in real time during surgery by using indocyanine green (ICG) lymphangiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Surgical Technique<\/jats:title>\n                    <jats:p>A 56\u2010year\u2010old woman received a diagnosis of a treatment\u2010resistant left chylothorax associated with LAM. To identify the chyle fistula during surgery, 1\u2009mL of ICG (2.5\u2009mg) was injected into both inguinal lymph nodes under ultrasound guidance after anesthesia, with 1\u2009mL per side for a total of 5\u2009mg of ICG. We performed video\u2010assisted thoracic surgery and observed near\u2010infrared light acquisition and overlay technology using Stryker. Approximately 1\u2009h after administration, fluorescence was observed in the anterior mediastinal lymph nodes, and a chyle fistula was observed around them. Although we attempted ligation of the lymph trunk, the surgical procedure damaged well\u2010developed lymph vessels. The damaged area and anterior mediastinal lymph nodes, including the surrounding lymph vessels, were incinerated using soft coagulation and covered with polyglycolic acid sheets and fibrin glue. Consequently, the amount of chylous effusion decreased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The use of ICG allowed visualization of the lymphatic pathway and location of the chyle fistula in real time during surgery, enabling precise local treatment to reduce chyle effusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ases.70067","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:21:13Z","timestamp":1745194873000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Real\u2010Time Identification of Lymph Vessels Using Indocyanine Green in a Patient With Chylothorax Associated With Lymphangioleiomyomatosis"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5242-0214","authenticated-orcid":false,"given":"Shinichi","family":"Sakamoto","sequence":"first","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Toba","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayaka","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Takehara","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taihei","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Endocrine Surgery and Oncology, Institute of Biomedical Sciences Tokushima University Graduate School  Tokushima 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