{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:33:03Z","timestamp":1772987583180,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"vor","delay-in-days":180,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Pelvic exenteration (PE) for rectal cancer is highly invasive. The trans\u2010anal approach (Ta\u2010PE) offers a minimally invasive alternative. This study evaluates the perioperative and long\u2010term outcomes of laparoscopic\u2010assisted Ta\u2010PE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on 17 patients who underwent laparoscopic\u2010assisted Ta\u2010PE with preserving anal sphincter between April 2018 and September 2024. Perioperative and oncological outcomes, including operative time, complications, hospital stay, and survival rates, were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median age was 64\u2009years (nine men, eight women). Total\u2010PE was performed in 11 patients (64.7%), and posterior\u2010PE in 6 (35.3%). Urinary diversion was required in 13 (76.5%). Mean operative time was 464\u2009min, with no conversions. Clavien\u2013Dindo Grade III\u2013IV complications occurred in four cases (23.5%), including pelvic abscess (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093) and postoperative bleeding (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). No reoperations or 90\u2010day mortality were observed. The median hospital stay was 21\u2009days. Three\u2010year overall survival, disease\u2010free survival, and local control rates were 69.9%, 45.4%, and 93.8%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Laparoscopic\u2010assisted Ta\u2010PE is a promising minimally invasive option for locally advanced rectal cancer, with favorable perioperative outcomes and effective local disease control. Larger studies are needed to confirm these findings and refine patient selection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ases.70110","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T23:44:43Z","timestamp":1751327083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Short\u2010Term and 3\u2010Year Oncological Outcomes in Laparoscopic\u2010Assisted Trans\u2010Anal Pelvic Exenteration With Preserving Anal Sphincter for Locally Advanced Rectal Cancer"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5878-4870","authenticated-orcid":false,"given":"Takashi","family":"Nonaka","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology Nagasaki University Graduate School of Biological Sciences  Nagasaki 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