{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:37:56Z","timestamp":1792820276791,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":183,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>A high proportion of elderly patients have multiple comorbidities, and postoperative complications may contribute to poor outcomes. The purpose of this study is to investigate whether operation time could affect the occurrence of postoperative complications in elderly patients who have undergone colorectal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study included 1316 colorectal cancer patients aged \u2265\u200980\u2009years who underwent colorectal cancer surgery between 2016 and 2024. We classified patients into two groups based on operative time (\u2265\u2009250\u2009min [\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009418] and &lt;\u2009250\u2009min [\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009898]). Clinical and perioperative features were compared between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Blood loss was higher (39\u2009mL vs. 16\u2009mL;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), postoperative complications were higher (30.4% vs. 19.8%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and hospital stay was longer (16\u2009days vs. 14\u2009days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) in the \u2265\u2009250 group. Multivariate analysis revealed that open surgery (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003; odds ratio 2.438; 95% confidence interval 1.350\u20134.402) and operative time \u2265\u2009250\u2009min (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004; odds ratio 1.966; 95% confidence interval 1.233\u20133.135) were independent predictors for postoperative severe complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In elderly patients undergoing colorectal cancer surgery, high\u2010risk cases should be managed by expert surgeons using minimally invasive techniques and with efforts to minimize operative time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ases.70341","type":"journal-article","created":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:36:03Z","timestamp":1783143363000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Operative Time on Postoperative Severe Complications in Elderly Patients With Colorectal Cancer: A Multicenter Retrospective Study"],"prefix":"10.1111","volume":"19","author":[{"given":"Mariko","family":"Yamashita","sequence":"first","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery Nagasaki University Graduate School of Biomedical Sciences  Nagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology, Department of Surgery Nagasaki University Graduate School of Biomedical Sciences  Nagasaki 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