{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:37:15Z","timestamp":1792816635532,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":208,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Asian J Endoscop Surgery"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Single\u2010incision appendectomy (SIA), including laparoscopic and laparoscopic\u2010assisted techniques, offers superior cosmetic outcomes and is increasingly applied to both uncomplicated and complicated cases of acute appendicitis. In our practice, transumbilical laparoscopic\u2010assisted appendectomy is the initial approach for all patients with acute appendicitis. This retrospective cohort study aimed to identify risk factors associated with conversion from SIA to multiport appendectomy (MPA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed medical records of patients aged &lt;\u200915\u2009years who underwent appendectomy for acute appendicitis at our hospital between April 2018 and June 2025. Patients were categorized into two groups: the SIA group and the MPA group, based on whether the procedure was completed as SIA or required conversion to MPA. Perioperative variables were compared between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 129 patients were included in this study. Of these, 79 (61.2%) were in the SIA group and 50 (38.8%) were in the MPA group. Univariate analysis revealed significant intergroup differences in preoperative C\u2010reactive protein (CRP) levels, maximal appendiceal diameter on preoperative imaging, time from symptom onset to hospital visit (&gt;\u200924\u2009h), and sex. Multivariate exploratory stepwise logistic regression analysis identified elevated preoperative CRP levels (odds ratio [OR], 1.12; 95% confidence interval [CI], 1.03\u20131.21;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009) and female sex (OR, 2.72; 95% CI, 1.23\u20136.04;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014) as independent risk factors for conversion.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Elevated preoperative CRP levels and female sex were significantly associated with difficulty in completing SIA; larger prospective studies are warranted to validate these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ases.70359","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T11:42:41Z","timestamp":1785238961000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive Factors for Conversion From Single Incision Appendectomy to Multiport Appendectomy for Pediatric Acute Appendicitis: A Single\u2010Center, Retrospective Cohort Study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6680-1343","authenticated-orcid":false,"given":"Ko","family":"Miyazaki","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Fukuoka Children's Hospital  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Hayashida","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Fukuoka Children's Hospital  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoma","family":"Koga","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Fukuoka Children's Hospital  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Tamaki","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Fukuoka Children's Hospital  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010020\u201004544\u20103"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900906"},{"issue":"7","key":"e_1_2_13_4_1","first-page":"588","article-title":"Laparoscopic Appendectomy Using a Single Umbilical Puncture (Minilaparoscopy)","volume":"37","author":"Pelosi M. A.","year":"1992","journal-title":"Journal of Reproductive Medicine"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984\u20100462\/;2019;37;2;00012"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2018.08.050"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2017.02.002"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595\u2010024\u201002896\u2010w"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010018\u20104806\u20104"},{"issue":"4","key":"e_1_2_13_10_1","first-page":"328","article-title":"An Operable Prediction Model of Emergency Transumbilical Single\u2010Incision Laparoscopic\u2010Assisted Appendectomy (In Japanese)","volume":"78","author":"Amano T.","year":"2020","journal-title":"Journal of Tokyo Medical University"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.3393\/jksc.2011.27.3.122"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017\u2010016\u20100081\u20106"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.2185\/jjrm.73.21"},{"issue":"4","key":"e_1_2_13_14_1","first-page":"434","article-title":"A Study of Transumbilical Extracorporeal Stump Closure in Laparoscopic Appendectomy (In Japanese)","volume":"46","author":"Tokai H.","year":"2021","journal-title":"Journal of the Japan Association of Surgical Societies"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v6.i4.101"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010011\u20101912\u2010x"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010017\u20105618\u20106"}],"container-title":["Asian Journal of Endoscopic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ases.70359","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ases.70359","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ases.70359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:54:34Z","timestamp":1792814074000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ases.70359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/ases.70359"],"URL":"https:\/\/doi.org\/10.1111\/ases.70359","archive":["Portico"],"relation":{},"ISSN":["1758-5902","1758-5910"],"issn-type":[{"value":"1758-5902","type":"print"},{"value":"1758-5910","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-02-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70359"}}