{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:04:29Z","timestamp":1792073069087,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T00:00:00Z","timestamp":1448496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Science Journal"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>For this study, we aimed to assess the dose\u2013response antiosteoporotic effects of the middle section of velvet antlers (VAs) from sika deers (<jats:italic>Cervus nippon<\/jats:italic>) fed with different types of fodders. VAs prepared from farmed sika deers fed with feed mixtures containing sorghum distillery residue (VA\u2010SDR) or without SDR (SDR replaced with hay, VA\u2010Hay) were divided into upper (VAU), middle (VAM) and basal (VAB) sections. The chemical constituents of the middle sections obtained from each VA type were compared, and their antiosteoporotic activities were evaluated using rats with ovaries removed surgically (ovariectomy, OVX). The VA\u2010Hay exhibited markedly increased iron and cysteine levels, whereas the VA\u2010SDR exhibited markedly increased level of alcoholic extract and testosterone. Both VA\u2010Hay\u2010 and VA\u2010SDR\u2010treated rats exhibited increased femur strength compared with the control group. However, VA\u2010SDR exhibited greater bone\u2010strengthening effects than did VA\u2010Hay. The serum osteocalcin and estradiol levels were significantly moderated in the VA\u2010Hay group alone. These results suggest that VA\u2010SDR and VA\u2010Hay prevent the loss of bone strength, and preserve trabecular architecture connectivity in an estrogen\u2010deficient state. However, differences in the chemical compositions of different forages may be responsible for the varying antiosteoporotic mechanisms observed. Thus, the addition of SDR in deer forage may enhance antiosteoporosis activity in VAs, and confer considerable economic and ecological benefits.<\/jats:p>","DOI":"10.1111\/asj.12536","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T11:11:52Z","timestamp":1448536312000},"page":"989-996","source":"Crossref","is-referenced-by-count":11,"title":["Effects of different forages on the chemical compositions and antiosteoporotic activities of velvet antlers"],"prefix":"10.1111","volume":"87","author":[{"given":"Sung\u2010Hui","family":"Tseng","sequence":"first","affiliation":[{"name":"School of Medicine, College of Medicine Taipei Medical University  Taipei Taiwan"},{"name":"Orthopedics Research Center Taipei Medical University Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lih\u2010Geeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Biopharmaceuticals, College of Life Sciences National Chiayi University  Chiayi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying\u2010Jang","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Food Science National Quemoy University  Kinmen County Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun\u2010Teng","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, College of Pharmacy Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Chiung","family":"Wang","sequence":"additional","affiliation":[{"name":"Orthopedics Research Center Taipei Medical University Hospital  Taipei Taiwan"},{"name":"School of Pharmacy, College of Pharmacy Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.05.030"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665112002820"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjp.2008.305"},{"key":"e_1_2_5_5_1","first-page":"80","article-title":"Health benefits of deer and elk velvet antler supplements: a systematic review of randomised controlled studies","volume":"125","author":"Gilbey A","year":"2012","journal-title":"New Zealand Medical Journal"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.108.100586"},{"key":"e_1_2_5_7_1","first-page":"15","article-title":"The effect of Sorghum Distillery Residue food additive on growth characteristics and antioxidant ability in Taiwan black feather native chickens","volume":"52","author":"Hsin HC","year":"2011","journal-title":"Tunghai Journal"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mambio.2008.07.005"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf304967t"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1755-8794-2-2"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2013.05.027"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2011.10.026"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2007-0433"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1638\/2011-0132.1"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf901367u"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2007.04.020"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-1112"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.24278"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-9574LSF"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.07.021"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.2000.1779"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2012.658110"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules170910574"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.10.060"},{"key":"e_1_2_5_25_1","first-page":"233","article-title":"Extraction of functional compounds from sorghum distillery residues","volume":"48","author":"Tung CH","year":"2010","journal-title":"Taiwanese Journal of Agricultural Chemistry and Food Science"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2011.01.005"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.08.029"}],"container-title":["Animal Science Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fasj.12536","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/asj.12536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T16:11:13Z","timestamp":1696349473000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/asj.12536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,26]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/asj.12536"],"URL":"https:\/\/doi.org\/10.1111\/asj.12536","archive":["Portico"],"relation":{},"ISSN":["1344-3941","1740-0929"],"issn-type":[{"value":"1344-3941","type":"print"},{"value":"1740-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,26]]}}}